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Curr Top Microbiol Immunol. 2005;287:1–30.

In addition to the SARS coronavirus (treated separately elsewhere in this volume), the complete genome sequences of six species in the coronavirus genus of the coronavirus family [avian infectious bronchitis virus-Beaudette strain (IBV-Beaudette), bovine coronavirus-ENT strain (BCoV-ENT), human coronavirus-229E strain (HCoV-229E), murine hepatitis virus-A59 strain (MHV-A59), porcine transmissible gastroenteritis-Purdue 115 strain (TGEV-Purdue 115), and porcine epidemic diarrhea virus-CV777 strain (PEDV-CV777)] have now been reported. Their lengths range from 27,317 nt for HCoV-229E to 31,357 nt for the murine hepatitis virus-A59, establishing the coronavirus genome as the largest known among RNA viruses.

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Cells can both survive and multiply under more stress than previously thought, shows research from the Faculty of Health and Medical Sciences.

This was found by inhibiting the essential gene DNA polymerase alpha, or POLA1, which initiates DNA replication during .

The discovery gives researchers new insights into DNA replication and may potentially be used for a new type of cancer treatment. Research Leader and Associate Professor Luis Toledo of the Center for Chromosome Stability at the Department of Cellular and Molecular Medicine states as follows:

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Under the watchful eye of a microscope, busy little blobs scoot around in a field of liquid—moving forward, turning around, sometimes spinning in circles. Drop cellular debris onto the plain and the blobs will herd them into piles. Flick any blob onto its back and it’ll lie there like a flipped-over turtle.

Their behavior is reminiscent of a microscopic flatworm in pursuit of its prey, or even a tiny animal called a water bear—a creature complex enough in its bodily makeup to manage sophisticated behaviors. The resemblance is an illusion: These blobs consist of only two things, skin cells and heart cells from frogs.

Writing today in the Proceedings of the National Academy of Sciences, researchers describe how they’ve engineered so-calleds (from the species of frog, Xenopus laevis, whence their cells came) with the help of evolutionary algorithms. They hope that this new kind of organism—contracting cells and passive cells stuck together—and its eerily advanced behavior can help scientists unlock the mysteries of cellular communication.

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Hod Hasharon-based BATM Advanced Communications Limited announced that they have developed a new diagnostic kit to detect the novel coronavirus.

As the CEO of the company Dr. Zvi Marom explained to The Jerusalem Post, compared to the kit that is currently used by hospitals all over the world, the product conceived by BATM has the advantage of being faster and more accurate and, within a few weeks, the company aims to set the cost at approximately NIS 1 per test. The kit is expected to be CE approved next week.

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Artist’s concept of the AREE Venus rover. The rover would be wind-powered and able to last on Venus’ hellish surface much longer than previous landers. Image via NASA/ JPL-Caltech.

There’ve been missions to Venus over the past decades, but Venus is a tough place to visit, with temperatures on its surface hot enough to melt lead. The last probe that landed on Venus’ hellish surface was part of the Vega 2 mission in 1985; it transmitted data from Venus’ surface for 57 minutes. Now NASA wants to visit Venus’ surface again, not with just another lander … but with a rover.

On February 21, 2020, NASA announced a public challenge to help design a future Venus rover called Automaton Rover for Extreme Environments (AREE). The challenge – Exploring Hell: Avoiding Obstacles on a Clockwork Rover – is specifically to develop an obstacle-avoidance sensor for the rover. The concept is being funded by a grant from the NASA Innovative Advanced Concepts program.

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