Blog – Page 8183

Clinicians and mechanical engineers from University College London (UCL) worked with Mercedes to create the continuous positive airway pressure (CPAP) device, which has been approved by the NHS.

The potentially life-saving technology has already been used in China, where coronavirus first emerged in December, and also in hospitals in Italy — the epicentre of the pandemic in Europe. The device helps COVID-19 patients with serious lung infections caused by the disease — such as pneumonia — to breathe more easily, when oxygen alone does not prove sufficient.

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Formula One teams are among the British firms joining forces to provide UK hospitals with vital equipment for COVID-19 patients.

Just like any other virus, the coronavirus needs a host to survive. Viruses enter the cells of the human body to cause disease by attaching to a specific receptor site on the host cell membrane. To do this, they attach to proteins in the capsid through glycoproteins found in the envelope of the virus.

Now, infection biologists form the German Primate Center — Leibniz Institute for Primate Research in Göttingen, together with colleagues at Charité – Universitätsmedizin Berlin, have found how the novel coronavirus SARS-CoV-2 penetrates the cells.

Can intravenous administration of high-dose vitamin C reduce organ failure scores and biomarkers of inflammation and vascular injury among patients with sepsis and acute respiratory distress syndrome (ARDS)?

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This randomized clinical trial compares the effects of treatment with intravenous vitamin C, hydrocortisone, and thiamine compared with intravenous hydrocortisone alone on duration of time alive and free of vasopressor use over 7 days in patients with septic shock.

Tomoko Fujii, MD, PhD; Nora Luethi, MD; Paul J. Young, MBChB, PhD; Daniel R. Frei, BSc, MBChB; Glenn M. Eastwood, PhD; Craig J. French, MB, BS; Adam M. Deane, MB, BS, PhD; Yahya Shehabi, MB, BS, PhD; Ludhmila A. Hajjar, MD, PhD; Gisele Oliveira, MD; Andrew A. Udy, MBChB, PhD; Neil Orford, MB, BS, PhD; Samantha J. Edney, BSN; Anna L. Hunt, BN, PGDipHSM, PGDipClinRes; Harriet L. Judd, BSN, PGDipHC; Laurent Bitker, MD; Luca Cioccari, MD; Thummaporn Naorungroj, MD; Fumitaka Yanase, MD; Samantha Bates, BN, PGDipCritCare; Forbes McGain, MB, BS, PhD; Elizabeth P. Hudson, MD; Wisam Al-Bassam, MBChB; Dhiraj Bhatia Dwivedi, BScNsg, MBA; Chloe Peppin, BN, PGDipCritCare; Phoebe McCracken, MPH; Judit Orosz, MD; Michael Bailey, PhD; Rinaldo Bellomo, MD, PhD; for the VITAMINS Trial Investigators.