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One major concern this time of year is how to undo the excess of the holidays. Helping the gut microbiome is a start. Health-Ade Kombucha is a fermented tea that contains probiotics—the same stuff you get from miso, sauerkraut, and yogurt—which can help add to the healthy bacteria in your gut. Have a serving in the morning to aid in digestion throughout the day.

A group of scientists from the Russian Academy of Sciences (ICG SB RAS) and the TSU Biological Institute has established a path through which nanoparticles of viruses and organic and inorganic substances from the environment enter the brain. Additionally, the researchers report a simple and inexpensive way to block their entry. The data obtained by the project could play a large role in medicine and pharmaceuticals, where nanoparticles are increasingly used for the diagnosis and treatment of serious diseases.

“There are a large number of nanoparticles of a wide variety of chemical elements and their compounds in the environment, ranging from harmless to toxic, for example, heavy metal oxides,” says Mikhail Moshkin, director of the Center for Laboratory Animal Genetic Resources of the ICG SB RAS. “Scientists have accumulated data that indicate the adverse effect of nanoparticles, for example, people who live closer than 50 meters to large highways may develop neurodegenerative diseases (Alzheimer’s, Parkinson’s and others) due to the accumulation of nanosized particles in the brain.”

The researchers sought to determine how nanoparticles enter the brain. They cannot penetrate through the lungs and blood vessels because the blood-brain barrier blocks them from the brain. Experiments conducted on rodents helped calculate the trajectory of the movement of nanoparticles.

Do you ever wish you could just turn on the happy chemicals in your brain? Imagine how much easier it would make getting out of bed each morning, getting even the most tedious parts of your job done, and finding the energy to consistently show up as your best self for the people you care about the most. But is it really possible – never mind advisable – to try and train our brains for more happiness?

“The quest for good feelings is nature’s survival engine,” explained Professor Loretta Breuning, founder of the Inner Mammal Institute, when I interviewed her recently. “For example, animals seek food to relieve the bad feeling of hunger. They seek warmth to relieve the bad feeling of cold. And happy chemicals start flowing before a mammal even eats or warms up because the brain turns them on as soon as it sees a way to meet a need.”

In 1900, so the story goes, prominent physicist Lord Kelvin addressed the British Association for the Advancement of Science with these words: “There is nothing new to be discovered in physics now.”

How wrong he was. The following century completely turned physics on its head. A huge number of theoretical and experimental discoveries have transformed our understanding of the universe, and our place within it.

Don’t expect the next century to be any different. The universe has many mysteries that still remain to be uncovered – and new technologies will help us to solve them over the next 50 years.

Someone reinvented the wheelchair, giving people who can’t walk more independence.

Scientists at the Faculty of Physics and Engineering, working with the Tomsk company Scientific and Production Center Chemical Technologies, have created and tested an improved model of a hybrid rocket engine. The team synthesized new fuel components that increased its calorie content, and therefore its efficiency.

The development emerged from a project to improve the design of a solid–fuel hybrid rocket engine and the fuel used in such engines. The scientists mathematically modeled an optimized engine and made fuel compositions based on aluminum diboride and dodecaboride. This is one of the most promising areas increasing fuel efficiency.

Rocket fuel with the addition of the components proposed by TSU specialists is distinguished by the highest calorific value, which characterizes fuel efficiency. Alexander Zhukov, professor at the Department of Mathematical Physics says that boron is the highest-energy solid component known today, but directly introducing it into the fuel is inefficient because a dense oxide film forms, leading to a high degree of burning out. But in combination with aluminum, boron burns well and increases energy.

In 2019, emerging technologies such as AI, robotics, and biotech made headlines. Here’s a list of 50+ stories that caught our eye this year.

Epigenetic reprogramming. “We are very radical life extensionists, neither healthspan increase no morbidity compression are enough, we would like to add decades if not centuries to the human lifespan.”

Yuri Deigin Founder of Youthereum, speaking at Master Investor’s Investing in the Age of Longevity 2019 event.

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