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Coronavirus patients taking hydroxychloroquine, a treatment touted by President Trump, were no less likely to need mechanical ventilation and had higher deaths rates compared to those who did not take the drug, according to a study of hundreds of patients at US Veterans Health Administration medical centers.

The study, which reviewed veterans’ medical charts, was posted Tuesday on medrxiv.org, a pre-print server, meaning it was not peer reviewed or published in a medical journal. The research was funded by the National Institutes of Health and the University of Virginia.

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An enduring question in geology is when Earth’s tectonic plates began pushing and pulling in a process that helped the planet evolve and shaped its continents into the ones that exist today. Some researchers theorize it happened around four billion years ago, while others think it was closer to one billion.

A research team led by Harvard researchers looked for clues in (older than 3 billion years) from Australia and South Africa, and found that these plates were moving at least 3.2 billion years ago on the early Earth. In a portion of the Pilbra Craton in Western Australia, one of the oldest pieces of the Earth’s crust, scientists found a latitudinal drift of about 2.5 centimeters a year, and dated the motion to 3.2 billion years ago.

The researchers believe this shift is the earliest proof that modern-like plate motion happened between two to four billion years ago. It adds to growing research that tectonic movement occurred on the early Earth. The findings are published in Science Advances.

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Unknown activists have posted nearly 25,000 email addresses and passwords allegedly belonging to the National Institutes of Health, the World Health Organization, the Gates Foundation and other groups working to combat the coronavirus pandemic, according to the SITE Intelligence Group, which monitors online extremism and terrorist groups.

While SITE was unable to verify whether the email addresses and passwords were authentic, the group said the information was released Sunday and Monday and almost immediately used to foment attempts at hacking and harassment by far-right extremists. An Australian cybersecurity expert, Robert Potter, said he was able to verify that the WHO email addresses and passwords were real.

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THE HAGUE, Netherlands (AP) — All it took was a few sturdy swings with a sledgehammer and a prized painting by Vincent van Gogh was gone.

A Dutch crime-busting television show has aired security camera footage showing how an art thief smashed his way through reinforced glass doors at a museum in the early hours of March 30. He later hurried out through the museum gift shop with a Vincent van Gogh painting tucked under his right arm and the sledgehammer in his left hand.

Police hope that publicizing the images will help them track down the thief who stole Van Gogh’s “The Parsonage Garden at Nuenen in Spring 1884” from the Singer Laren Museum while it was shut down due to coronavirus containment measures.

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The US government has contingency plans in place in the event North Korean dictator Kim Jong Un should die after reports that his health was in grave condition.

Sources discussed the plans but urged caution about the veracity of the reports, which claimed Kim is in bad shape after a cardiovascular procedure, Fox News reported.

Those plans include the possibility of a mass-scale humanitarian crisis inside the hermit nation such as a famine, according to the report.

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SINGAPORE — Less than a week after a record 12.9 tonnes of pangolin scales were seized from a container by the authorities here, another 12.7 tonnes have been uncovered in a joint operation by the National Parks Board (NParks), Singapore Customs and the Immigration and Checkpoints Authority (ICA).

The 40ft (12m) container that was on its way by ship from Nigeria to Vietnam was declared to contain “cassia seeds” but was found on Monday (April 8) to be holding the animal parts, estimated to be worth about $51.6 million, in 474 bags at the Pasir Panjang Scanning Station.

The haul came from two species, the white-bellied tree pangolin (Phataginus tricuspis) and the giant ground pangolin (Smutsia gigantea) and are likely to have come from 21,000 pangolins.

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An artificial neural network can reveal patterns in huge amounts of gene expression data, and discover groups of disease-related genes. This has been shown by a new study led by researchers at Linköping University, published in Nature Communications. The scientists hope that the method can eventually be applied within precision medicine and individualised treatment.

It’s common when using social media that the platform suggests people whom you may want to add as friends. The suggestion is based on you and the other person having common contacts, which indicates that you may know each other. In a similar manner, scientists are creating maps of biological networks based on how different proteins or genes interact with each other. The researchers behind a new study have used artificial intelligence, AI, to investigate whether it is possible to discover biological networks using deep learning, in which entities known as “artificial neural networks” are trained by experimental data. Since artificial neural networks are excellent at learning how to find patterns in enormous amounts of complex data, they are used in applications such as image recognition. However, this machine learning method has until now seldom been used in biological research.

“We have for the first time used deep learning to find disease-related genes. This is a very powerful method in the analysis of huge amounts of biological information, or ‘big data’,” says Sanjiv Dwivedi, postdoc in the Department of Physics, Chemistry and Biology (IFM) at Linköping University.

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Chinese research i think.

Developing an effective universal influenza vaccine against influenza virus with highly conserved antigenic epitopes could induce a broad-spectrum immune response to prevent infection.

(An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. For example, the epitope is the specific piece of the antigen to which an antibody binds. See picture1)

Vaccination is the most effective way to prevent influenza virus infection. Current influenza vaccines are based on induction of protective antibodies against the viral surface hemagglutinin (HA) protein, which can effectively neutralize the influenza virus and significantly reduce morbidity and mortality. However, owing the variability of HA, vaccine strains need to be changed every year.

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