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Scientists have successfully transplanted functional miniature livers into rats, after growing the bioengineered organs in the lab from reprogrammed human skin cells.

The experiment, which gave the animals working liver organs, could lay the groundwork for future treatments to address terminal liver failure – a disease that claims the lives of over 40,000 people in the US every year.

While there’s still a lot of work to be done before the technique can directly aid human patients, the researchers say their proof of concept may help underpin a future alternative to liver transplants, which are often incredibly expensive procedures to perform, in addition to being strictly limited by donor supply.

Although promising, convalescent plasma has not yet been shown to be safe and effective as a treatment for COVID-19. Therefore, it is important to study the safety and efficacy of COVID-19 convalescent plasma in clinical trials.

Pathways for use of investigational COVID-19 convalescent plasma

The following pathways are available for administering or studying the use of COVID-19 convalescent plasma:

SpaceX will launch its next batch of Starlink internet satellites into orbit tonight (June 3) after two weeks of weather delays and the company’s historic first astronaut flight.

A Falcon 9 rocket, which SpaceX has already flown four past missions, will launch 60 new Starlink satellites into orbit from the company’s pad at Launch Complex 40 at Cape Canaveral Air Force Base in Florida. Liftoff is set for 9:25 p.m. EDT (0125 June 4 GMT).

“That’s very early,” Anna Durbin, a vaccine researcher at Johns Hopkins University, told STAT. “We don’t know if those antibodies are durable.”

The Moderna press release also indicated that the antibody levels observed were equal to or greater in the 100 ug dose than was seen in patients who recovered from COVID-19. There’s not much context here, because studies on recovered COVID-19 patients have shown a range that is potentially influenced by the severity of the disease. For example, John “Jack” Rose, a Yale University vaccine researcher told STAT about a study in China demonstrating that in 175 recovered COVID-19 patients, 10 had no detectable neutralizing antibodies, while others had very high antibody levels.

Of the Phase III trial, Fauci indicated that the majority of trial participants will be between the ages of 18 and 55, but will include elderly Americans that are most at risk of serious illness from COVID-19.

73 years ago, the same scientists who had helped to begin the atomic age set a “doomsday clock” for humanity. It first appeared on the cover of the June 1947 issue of the Bulletin of the Atomic Scientists as a dire warning about the nuclear rivalry between the U.S. and the Soviet Union. At that moment, the Bulletin estimated that we stood at about 7 minutes to midnight, which represented nuclear apocalypse.

The Doomsday Clock wasn’t – and still isn’t – a precise countdown to the end of all things. It’s a metaphor for how dangerous the global situation seems to be at a given moment, in the very well-informed but also subjective opinion of the Bulletin’s board of directors. In June 1947, things looked dire. The U.S. had dropped a pair of atomic bombs on Japan less than two years before; when the Bulletin of the Atomic Scientists first published the Doomsday Clock image, researchers were still studying the aftermath of those bombs. Meanwhile, the Soviet Union was hard at work on its own atomic program, and was just a couple of years away from testing its first atomic bomb in 1949.

Through the Cold War and in the decades since, the clock’s minute hand has moved about two dozen times. In September 1953, it stood at two minutes to midnight, following Russia’s August 1953 hydrogen bomb test – which in turn had followed a U.S. hydrogen bomb test in November 1952. Those tests meant the two feuding superpowers each had much more powerful new weapons with which to destroy each other; the tests also heightened the sense of life-or-death competition that made it more likely that someone would decide to use those terrible new bombs.

A Tesla owner has demonstrated a rather novel way to charge his Model 3. In a recent video, Sean Callaghan of the ItsYeBoi YouTube channel opted to use a series of off-the-shelf solar panel sheets onto a towable trailer to create a mobile charging unit for his all-electric sedan.

Callaghan planned to use only the sun and the solar sheets purchased from e-commerce platform Wish to charge his Model 3. The solar panel sheets would collect energy from the sun and transfer it to a control panel. The control panels were connected to batteries that would hold the energy—the batteries connected to an inverter, which would then charge the Tesla Model 3.

The entire assembly would provide the Model 3 with about 800 watts of energy on a completely sunny day. However, Callaghan shot the video when weather was overcast, so the entire solar panel trailer build only managed to provide around 300 watts throughout the YouTube host’s test.

UNIVERSITY PARK, Pa. — Phone, keys, wallet…ultraviolet light device. Just in case you wanted yet another item to carry around all day, researchers say that portable, handheld COVID-19 killing ultraviolet light devices may be a reality in the future. These gadgets would emit high-intensity ultraviolet light and quickly disinfect targeted areas.

There are two main ways to clean and remove bacteria and viruses from a given surface: chemicals and ultraviolet (UV) radiation exposure. UV radiation between 200 and 300 nanometers can effectively kill a virus and stop it from replicating itself. Obviously, devices emitting UV rays would come in handy these days due to COVID-19, but as of now such devices require an expensive, bulky mercury-containing gas discharge lamp with a short battery life.

The study’s authors, however, believe that much more portable, longer lasting, energy efficient, and environmentally friendly UV light emitting diodes can be developed. The necessary LEDs already exist, but the process has been complicated by the fact that electrode materials must also be transparent.