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Apr 14, 2020

CRISPR-Cas9 successfully reverses type 2 diabetes in mice

Posted by in categories: biotech/medical, genetics

Circa 2019


Researchers at Hanyang University, South Korea, have used the gene-editing technology CRISPR-Cas9 to treat obesity and type 2 diabetes in mice, a development that could eventually benefit humans. The therapy specifically reduced fat tissue and reversed obesity-related metabolic disease in the animals.

Apr 14, 2020

Physicists to improve plasma fusion mirror devices with $5 million grant

Posted by in categories: nuclear energy, particle physics

Fusion research began in earnest in the 1960s, when scientists developed mirror machines. These linear tubes have pinched magnetic field lines on either end that act like mirrors, reflecting the charged plasma particles inward and retaining them and their heat in the machine. American researchers halted mirror research three decades ago, mainly due to an inability to contain the plasma.

WHAM will essentially take the team’s research back to the mirror machine days, but with significant upgrades.

“We hope to go well beyond what was done in the mirror program because we have access to very-high-field superconducting magnets like those being built by our partners for toroidal (donut-shaped) plasmas,” Forest says. “These magnets and heating systems simply weren’t available 20 years ago. It’s a new look at an older concept using new technology.”

Apr 14, 2020

North Korea fires barrage of missiles from ground and air

Posted by in categories: biotech/medical, existential risks, military

SEOUL, South Korea (AP) — A barrage of North Korean missiles fired from both the ground and fighter jets splashed down on the waters off the country’s east coast on Tuesday, South Korea’s military said, a show of force on the eve of a key state anniversary in the North and parliamentary elections in the rival South.

The back-to-back launches were the latest in a series of weapons tests that North Korea has conducted in recent weeks amid stalled nuclear talks and outside worries about a possible coronavirus outbreak in the country.

North Korean troops based in the eastern coastal city of Munchon first launched several projectiles — presumed to be cruise missiles — on Tuesday morning, South Korea’s Joint Chiefs of Staff said in a statement.

Apr 14, 2020

Humming greatly increases nasal nitric oxide

Posted by in category: biotech/medical

The paranasal sinuses are major producers of nitric oxide (NO). We hypothesized that oscillating airflow produced by humming would enhance sinus ventilation and thereby increase nasal NO levels. Ten healthy subjects took part in the study. Nasal NO was measured with a chemiluminescence technique during humming and quiet single-breath exhalations at a fixed flow rate. NO increased 15-fold during humming compared with quiet exhalation. In a two-compartment model of the nose and sinus, oscillating airflow caused a dramatic increase in gas exchange between the cavities. Obstruction of the sinus ostium is a central event in the pathogenesis of sinusitis. Nasal NO measurements during humming may be a useful noninvasive test of sinus NO production and ostial patency. In addition, any therapeutic effects of the improved sinus ventilation caused by humming should be investigated.

Apr 14, 2020

This Guy Says He Solved the Most Controversial Open Problem in Math

Posted by in category: mathematics

Has one of the major outstanding problems in number theory finally been solved? Or is the 600-page proof missing a key piece? The verdict isn’t in yet, but the proof, at least, will finally appear in a peer-reviewed journal.

However, there’s just one catch: the mathematician himself, Shinichi Mochizuki, is one of the journal’s seniormost editors.

Apr 14, 2020

NanoViricides, Inc. Progress on COVID-19 Drug Encouraging

Posted by in categories: biotech/medical, nanotechnology

The company’s update on its development of COVID-19 drug candidate is promising.

Vancouver, British Columbia—(Newsfile Corp. — March 31, 2020) — NanoViricides, Inc. (NYSE American: NNVC) (the “Company”) is a nano-biopharmaceutical Company at the development stage, with proprietary and patented drug development work focused on viral diseases. The Company’s research involves the use of a unique nanomedicine technology called nanoviricides — agents designed to “fool” a virus into attaching to an antiviral nanomachine, in the same way that the virus normally attaches to the receptors on a cell surface, but for the purpose of its neutralization and destruction. NanoViricides was highlighted by SmallCapsDaily for providing an update on its progress to develop a drug that can treat COVID-19, the coronaviral pneumonia disease which is caused by the SARS-CoV-2 virus, aka, 2019-nCoV, also known as the Wuhan coronavirus.

Apr 14, 2020

DARPA has a crappy new idea to help soldiers

Posted by in category: futurism

When you’re deployed to Iraq and your stomach starts to gak, diarrhea.

Apr 14, 2020

Higgs turning up everywhere, this time in paint

Posted by in categories: particle physics, quantum physics

:oooo circa 2009.


The portrait of Peter Higgs is on display at the University of Edinburgh’s School of Informatics. Photograph: Ken Currie.

It seems that Peter Higgs, despite his known aversion to publicity is turning up everywhere. Of course the potential discovery of the particle in the next few years by either/both of the Large Hadron Collider at CERN and the Tevatron at Fermilab is bringing a lot more attention to him, and a little to the other theorists, such as Guralnik, Hagen, Kibble, Brout, and Englert, who also developed the ideas behind a mass-giving spontaneously symmetry broken quantum field and its manifestation as a particle, now known as the Higgs boson. (Yep, that sounds scary because it gets technical.)

Continue reading “Higgs turning up everywhere, this time in paint” »

Apr 14, 2020

What do soap bubbles and butterflies have in common?

Posted by in category: genetics

Edith Smith bred a bluer and shinier Common Buckeye at her butterfly farm in Florida, but it took University of California, Berkeley, graduate student Rachel Thayer to explain the physical and genetic changes underlying the butterfly’s newly acquired iridescence.

Apr 14, 2020

Department of Energy Announces $32 Million for Lower-Cost Fusion Concepts

Posted by in categories: innovation, nuclear energy

WASHINGTON, D.C. — The U.S. Department of Energy today announced the winners of $32 million in funding for 15 projects as part of the Breakthroughs Enabling THermonuclear-fusion Energy (BETHE) program. These projects will work to develop timely, commercially viable fusion energy, with the goal to increase the number and performance levels of lower-cost fusion concepts.

“Fusion energy technology holds great potential to be a safe, clean, reliable energy source, but research and development of fusion technology is often constrained by prohibitive costs,” said Under Secretary of Energy Mark W. Menezes. “BETHE teams will build on recent progress in fusion research and the growing fusion community to lower costs and further foster viable commercial opportunities for the next generation of fusion technology.”

“These BETHE projects further advance ARPA-E’s commitment to the development of fusion energy as a cost-competitive, viable, energy generation source,” said ARPA-E Director Lane Genatowski. “Commercially viable fusion energy can improve our chances of meeting global energy demand and will further establish U.S. technological lead in this crucial area.”