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Researchers from the Max Delbrück Center for Molecular Medicine have developed a new tool that makes it easier to maximize the power of deep learning for studying genomics. They describe the new approach, Janggu, in the journal Nature Communications.

Imagine that before you could make dinner, you first had to rebuild the kitchen, specifically designed for each recipe. You’d spend way more time on preparation, than actually cooking. For computational biologists, it’s been a similar time-consuming process for analyzing . Before they can even begin their analysis, they spend a lot of valuable time formatting and preparing huge data sets to feed into deep learning models.

To streamline this process, researchers from MDC developed a universal programming tool that converts a wide variety of genomics data into the required format for analysis by deep learning models. “Before, you ended up wasting a lot of time on the technical aspect, rather than focusing on the biological question you were trying to answer,” says Dr. Wolfgang Kopp, a scientist in the Bioinformatics and Omics Data Science research group at MDC’s Berlin Institute of Medical Systems Biology (BIMSB), and first author of the paper. “With Janggu, we are aiming to relieve some of that technical burden and make it accessible to as many people as possible.”

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The origin of our teeth goes back more than 400 million years back in time, to the period when strange armored fish first developed jaws and began to catch live prey. We are the descendants of these fish, as are all the other 60,000 living species of jawed vertebrates — sharks, bony fish, amphibians, reptiles, birds and mammals. An international team of scientists led by Uppsala University (Sweden), in collaboration with the ESRF, the European Synchrotron (France), the brightest X-ray source, has digitally ‘dissected’, for the first time, the most primitive jawed fish fossils with teeth found near Prague more than 100 years ago. The results, published recently in Science, show that their teeth have surprisingly modern features.

Teeth in current jawed vertebrates reveal some consistent patterns: for example, new teeth usually develop on the inner side of the old ones and then move outwards to replace them (in humans this pattern has been modified so that new teeth develop below the old ones, deep inside the jawbone). There are, however, several differences between bony fish (and their descendants the land animals) and sharks; for example the fact that sharks have no bones at all, their skeleton is made of cartilage, and neither the dentine scales nor the true teeth in the mouth attach to it; they simply sit in the skin. In bony fish and land animals, the teeth are always attached to jawbones. In addition, whilst sharks shed their worn-out teeth entire, simply by detaching them from the skin, bony fish and land animals shed theirs by dissolving away the tooth bases.

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NASA’s most advanced Mars rover, Perseverance, will launch from Earth on 30 July on a mission to seek out signs of ancient microbial life on what was once a river delta three-and-a-half billion years ago.

NASA’s next rover to the Red Planet is slated to launch no earlier than July 30. These highlights will get you up to speed on the ambitious mission.

In less than a month, NASA expects to launch the Mars 2020 Perseverance mission from Cape Canaveral, Florida. Loaded with scientific instruments, advanced computational capabilities for landing, and other new systems, the Perseverance rover is the largest, heaviest, most sophisticated vehicle NASA has ever sent to the Red Planet.

Continue reading “7 Things to Know About the Mars 2020 Perseverance Rover Mission” | >

The amygdala is the brain’s surveillance hub: involved in recognizing when someone with an angry face and hostile body language gets closer, tamping down alarm when a honeybee buzzes past, and paying attention when your mother teaches you how to cross the street safely and points out which direction traffic will be coming from — in other words, things people should run away from, but also those they should look toward, attend to and remember.

In that sense, researchers say, this little knot of brain tissue shows just how tangled up emotion and social behavior are for humans. “Important events tend to be emotional in nature,” as do most aspects of social behavior, says John Herrington, assistant professor of psychiatry at the Children’s Hospital of Philadelphia in Pennsylvania.

As a result, the amygdala has long been a focus of autism research, but its exact role in the condition is still unclear.

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Singapore has just begun to get its second wave of coronavirus under control. Now, it’s on track to face its worst-ever outbreak of another viral infection: dengue.

More than 14,000 dengue cases have been reported in the city-state since the start of the year, according to the National Environment Agency (NEA). The total number for the whole year is expected to exceed the 22,170 cases reported in 2013 — the largest dengue outbreak in Singapore’s history, the agency said.

Dengue is a viral infection transmitted by the Aedes mosquito, the same insect responsible for spreading Zika, chikungunya and yellow fever. It is commonly found in hot, wet regions of the tropics and subtropics during the rainy months.

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Unlimited Clean Energy with The Wavestar machine. Harness the Power of Wave Energy with the World’s Strongest Wave Power Concept. Oceans cover more than 70% of Earth’s surface and ocean waves carry enormous power. By utilizing the largest source of untapped clean energy, it could supply a substantial part of the world’s electricity. Wave energy is more predictable compared to wind power, the waves come and go slowly and can be forecasted 24 hours ahead. Also the production continues 6–8 hours after the wind settles. This makes wave energy an ideal complement for wind turbines and could satisfy the continuously increasing demand for renewable energy in the grid.

The concept was invented by sailing enthusiasts Niels and Keld Hansen in 2000. The challenge was to create a regular output of energy from ocean swells and waves that are 5–10 seconds apart. This was achieved with a row of half-submerged buoys, which rise and fall in turn as the wave passes, forming the iconic part of Wavestar’s design. This allows energy to be continually produced despite waves being periodic.

The machine’s unique storm protection system, one of the many patented aspects of the design, guarantees the machine’s sea survivability and represents a real milestone in the development of wave energy machines. Wave energy will play a crucial role in securing our energy future, but only machines that can withstand the strongest storms will survive.

Environmental issues demand swift diversification to multiple renewable sources in order for us to fulfill our future energy needs. Wavestar will work in harmony with other clean energy methods to support the alternative energy movement and ensure a continuous supply of clean energy. Imagine what we can do together.

Continue reading “Ocean Power Plant Generates Energy From Waves — Unlimited Cheap Clean Electricity” | >