Lifeboat Foundation

Just as our human relationships and connections can nudge, push, or dramatically shift societal values and consequences, the connections between neurons form intricate networks that dictate the outcome of your mind. Your thoughts, memories, behaviors; your values, world view, mental health—everything that makes you you is calculated and stored in these connections, called synapses, that dot our brains like billions of stars in the night sky.

If a connectome—a large-scale snapshot of all your neural connections—is a loose “copy” of you at one moment in time, synapses are a fluid representation of how you change and grow through time. Similar to human connections, synapses come in different varieties and evolve as we age. Yet until now, capturing how these synapses change as we move through time has been nearly impossible.

Last week, in a technological tour-de-force, a European team from the United Kingdom, France, and Sweden, led by Dr. Seth G.N. Grant at the University of Edinburgh, redefined impossibility with a paper in Science. Peering into the brains of mice at different ages—one day, one week, and all the way up to an elderly 18 months—the team constructed maps of roughly 5 billion synapses, outlining a timeline of their diversity and numbers in over 100 different brain regions with age.

German herpetologist Mark Scherz has discovered a new species of diamond frog living in northern Madagascar.

Back in 2005, Drs. Irina and Michael Conboy showed that joining the circulatory systems of young and old mice together in a procedure called parabiosis could rejuvenate aged tissues and reverse some aspects of aging in old mice.

Following this discovery, many researchers concluded that there must be something special in young blood that was able to spur rejuvenation in aged animals, and various companies have been trying to find out what. Indeed, we recently reported that researchers were apparently successful in halving the epigenetic age of old rats by treating them with Elixir, a proprietary mix of pro-youthful factors normally found in young blood.

However, a question still remains: was the rejuvenation the result of there being something beneficial in the young blood, or is it more a case of dilution of the harmful factors present in old blood?

This would forever change our world.

Chemical process called ELAST allows labeling probes to infuse more quickly, and makes samples tough enough for repeated handling.

When there’s a vexing problem to be solved, people sometimes offer metaphorical advice such as “stretching the mind” or engaging in “flexible” thinking, but in confronting a problem facing many biomedical research labs, a team of MIT researchers has engineered a solution that is much more literal. To make imaging cells and molecules in brain and other large tissues easier while also making samples tough enough for years of handling in the lab, they have come up with a chemical process that makes tissue stretchable, compressible, and pretty much indestructible.

“ELAST” technology, described in a new paper in Nature Methods, provides scientists a very fast way to fluorescently label cells, proteins, genetic material, and other molecules within brains, kidneys, lungs, hearts, and other organs. That’s because when such tissues can be stretched out or squished down thin, labeling probes can infuse them far more rapidly. Several demonstrations in the paper show that even after repeated expansions or compressions to speed up labeling, tissues snap back to their original form unaltered except for the new labels.

The experiment raises major safety concerns for gene-edited babies.

On September 10, 2008, CERN’s Large Hadron Collider (LHC) fired up for the very first time. In the decade since, the world’s largest and most powerful particle accelerator has been responsible for some of the most important breakthroughs in scientific history, most notably the discovery of the Higgs boson in 2013. New Atlas is celebrating the 10-year anniversary with a look back at the LHC’s achievements and, with a massive new upgrade in the works, what physics puzzles it could help piece together in the future.

Not only is the Large Hadron Collider the world’s largest particle accelerator, it’s the world’s largest machine, full-stop. That’s thanks to a 27-km-long (16.7-mi) ring of pipes that house the particle beams, along with thousands of powerful magnets and an advanced cooling system of liquid helium.

The ring is made up of two separate tubes, with high-energy particle beams circling in opposite directions. Superconducting electromagnets accelerate the particles almost to the speed of light, and for those to work they need to be kept extremely cold: −271.3° C (−456.3° F) to be exact, which is colder than outer space. That’s where the liquid helium comes in, chosen because it’s the only known element to remain in a liquid form at such low temperatures.

“We have also partnered with Texas EquuSearch and the National Center for Missing and Exploited Children to tap into their resources as well. We have participated in ground and air searches on Fort Hood and throughout the central Texas region.” Grey said.

The soldier was last seen between 11:30 a.m. and 12:30 p.m. April 22 in the parking lot of 3rd Cavalry Regiment’s engineer squadron headquarters, where she worked in the armory room. Her car keys, barracks room key, identification card and wallet were later found there.

Researchers from the University of Bath have developed motion capture technology that enables you to digitize your dog without a motion capture suit and using only one camera.

The software could be used for a wide range of purposes, from helping vets diagnose lameness and monitoring recovery of their canine patients, to entertainment applications such as making it easier to put digital representations of dogs into movies and video games.

Motion capture technology is widely used in the entertainment industry, where actors wear a suit dotted with white markers which are then precisely tracked in 3D space by multiple cameras taking images from different angles. Movement data can then be transferred onto a digital character for use in films or computer games.