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In the present investigation, the SD rats were separated into two groups old control group and the treatment group (n = 8). The treatment group received four injections of E5 every alternate day for 8 days, and eight injections every alternate day for 16 days. Body weight, grip strength, cytokines, and biochemical markers were measured for more than 400 days of the study. Clinical observation, necropsy, and histology were performed. The E5 treatment exhibited great potential by showing significantly improved grip strength, remarkably decreased pro-inflammatory markers of chronic inflammation and oxidative stress, as well as biomarkers for vital organs (BUN, SGPT, SGOT, and triglycerides), and increased anti-oxidant levels. Clinical examinations, necropsies, and histopathology revealed that the animals treated with the E5 had normal cellular structure and architecture. In conclusion, this unique ‘plasma-derived exosome’ treatment (E5) alone is adequate to improve the health-span and extend the lifespan of the old SD rats significantly.

“The only journey is the one within”

Rainer Maria Rilke

Feedback loops within a system can generate seemingly contradictory or paradoxical relationships. A cognitive system might have an internal model of its mental processes, which influences its decision-making and behavior. This internal model then becomes part of the system’s overall state, creating a recursive loop where the system’s representation of itself affects its own behavior.

I expect this around 2029/2030, so about 5-ish years. Phase 1 of it will be: hey Ai, i didnt really like that level, mission, story line, etc… edits on the fly. Phase 2 of it will be creating DLC on the fly. And, Phase 3 will be just telling an AI roughly what you want to play, and it tries to build it.


Publishing giant Electronic Arts shows a concept of the different ways users could generate their own content in a game using generative AI.

What just happened? Researchers have successfully deployed a fully autonomous robot to inspect the inside of a nuclear fusion reactor. This achievement – the first of its kind – took place over 35 days as part of trials at the UK Atomic Energy Authority’s Joint European Torus facility.

JET was one of the world’s largest and most powerful operational fusion reactors until it was recently shut down. Meanwhile, the robotic star of the show was, of course, the four-legged Spot robot from Boston Dynamics, souped up with “localization and mission autonomy solutions” from the Oxford Robotics Institute (ORI) and “inspection payload” from UKAEA.

Spot roamed JET’s environment twice daily, using sensors to map the facility layout, monitor conditions, steer around obstacles and personnel, and collect vital data. These inspection duties normally require human operators to control the robot remotely.