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AgelessRx claims that PEARL is the first nationwide telemedicine trial and one of the first large-scale intervention trials on Longevity. The human trial is a stepping stone to the way to bringing rapamycin to the Longevity market. PEARL (Participatory Evaluation of Aging with Rapamycin for Longevity) is a $600,000 trial with the University of California. They will evaluate the safety and effectiveness of rapamycin in 200 healthy adults for Longevity in double-blind, randomized, placebo-controlled trial.

Interested patients will be screened for eligibility using telemedicine. Eligible patients include those aged 50–85 of any sex, any ethnicity, in relatively good health, with only well-managed, clinically stable chronic diseases.

TAME is a separate $75 million trial to clinically evaluate Metformin drugs for Longevity properties. TAME has a composite primary endpoint – of stroke, heart failure, dementia, myocardial infarction, cancer and death. Rather than attempting to cure one endpoint, it will look to delay the onset of any endpoint, extending the years in which subjects remain in good health – their healthspan. A $40 million donation has been combined with a $35 million NIH grant to fund the TAME trial.

In a study that gives new meaning to the term “rock bottom,” seismic researchers have discovered the underside of a rocky slab of Earth’s surface layer, or lithosphere, that has been pulled more than 400 miles beneath northeastern China by the process of tectonic subduction.

The study, published by a team of Chinese and U.S. researchers in Nature Geoscience, offers news evidence about what happens to water-rich oceanic tectonic plates as they are drawn through Earth’s beneath continents.

Rice University seismologist Fenglin Niu, a co-corresponding author, said the study provides the first high-resolution seismic images of the top and bottom boundaries of a rocky, or lithospheric, tectonic plate within a key region known as the mantle transition zone, which starts about 254 miles (410 kilometers) below Earth’s surface and extends to about 410 miles (660 kilometers).

Where do you typically go to get the most up-to-date news on anti-aging research studies?

I’ve been digging around and found some longevity journals and other resources but curious to know what else is out there.


One of the most-frequent questions prominent longevity experts get asked is, “How can I contribute?”

Dr. Aubrey de Grey typically responds that, “The main way to get involved other than donating, unless you’re a biologist and can help with the actual research, is in raising awareness.”

(next Monday, 23rd November)
Please pre-register at https://www.taufriends.ch/registration

Please pre-register at https://www.taufriends.ch/registration

“We are delighted to bring you access to two giants in the world of AI, 2020 Dan David laureates, Dr. Demis Hassabis, co-founder and CEO of DeepMind, the world’s leading AI research company, and Prof. Amnon Shashua, CEO and co-founder of Mobileye, the largest ever Israeli acquisition whose technology powers more than 55 million cars around the world today. Dr. Hassabis and Prof. Shashua will enlighten us on the potential of AI at an exclusive event in conjunction with the Dan David Prize on Monday, November 23, 2020.”

Video. Japan made robo-wolves to frighten off bears.

Pretty creative! 😃


The town of Takikawa on the northern island of Hokkaido purchased and installed a pair of the robots after bears were found roaming neighbourhoods in September. City officials said there have been no bear encounters since they deployed the robotic red-eyes blonde animal guardians were deploying ed to the city.

Pearls have long been favored as objects of beauty. Now, Purdue University innovators are using the gem to provide potential new opportunities for spectral information processing that can be applied to spectroscopy in biomedical and military applications.

The Purdue team demonstrated transport-assisted information processing by creating a .

Spectrometers probe interactions of matter and light as a function of the electromagnetic spectrum and are commonly used in biomedical and . For example, they have been used for diagnostics of various types of cancer and for military gas sensing.

Article from carbuzz.com. Was this human or AI error?


Semi-autonomous driving systems continue to come under the microscope, and the results are mixed. Tesla’s Autopilot system is one of the more well-known examples, and while some drivers like this Model 3 owner have faith in the technology, we have seen some disturbing instances of the system potentially leading to serious crashes.

Well, yet another Tesla was involved in a nasty crash and is a reminder that humans and driving aids don’t always make a safe combination. The video — recorded by the car’s camera system — was shared by GreenTheOnly on Twitter, a hacker who has previously uncovered some of the shortcomings of Tesla’s in-car tech. It’s not known what Tesla model this was.