Using this technique, the researchers were able to reduce tumour size in mice by between eight and nine times without harming healthy tissue. In the future, the team hopes to test this new therapy on patients with melanoma.
Superfluid helium, describable by a two-component order parameter, exhibits only the Bogolubov mode with energy $\to 0$ at long wavelengths, while a Lorentz-invariant theory with a two-component order parameter exhibits a finite energy mode at long wavelengths (the Higgs Boson), besides the above mass-less mode. The mass-less mode moves to high energies if it couples to electromagnetic fields (the Anderson-Higgs mechanism). Superconductors, on the other hand have been theoretically and experimentally shown to exhibit both modes. This occurs because the excitations in superconductors have an (approximate) particle-hole symmetry and therefore show a similarity to Lorentz-invariant theories.
Dev Genes Evol. 2012 Mar;222:29–44. doi: 10.1007/s00427-011‑0387-z. Epub 2012 Feb 23.
Gap junctional proteins are important components of signaling pathways required for the development and ongoing functions of all animal tissues, particularly the nervous system, where they function in the intracellular and extracellular exchange of small signaling factors and ions. In animals whose genomes have been sufficiently sequenced, large families of these proteins, connexins, pannexins, and innexins, have been found, with 25 innexins in the nematode Caenorhabditis elegans Starich et al. (Cell Commun Adhes 8: 311–314, 2001) and at least 37 connexins in the zebrafish Danio rerio Cruciani and Mikalsen (Biol Chem 388:253–264, 2009). Having recently sequenced the medicinal leech Hirudo verbana genome, we now report the presence of 21 innexin genes in this species, nine more than we had previously reported from the analysis of an EST-derived transcriptomic database Dykes and Macagno (Dev Genes Evol 216: 185–97, 2006); Macagno et al. (BMC Genomics 25:407, 2010).
Plastic has become ubiquitous in our home and work lives over the past 50 years. It is pliable, durable, easy to make, and hard to break. Plastic may be convenient and useful, but it also won’t break down naturally, which makes it a long-lasting pollutant. A recent study published in Science Advances found that humans have produced 8,300 million metric tons of plastic to date, which is 25,000 times the weight of the Empire State Building. Seventy nine percent of that has ended up in landfills or the ocean. If we continue making plastic at our current rate, that figure will reach 12,000 metric tons by the year 2050. Plastic pollutants are showing up in drinking water all over the world as well as in food products, like beer. We have a serious problem.
Humans are “addicted” to plastic, says Gavin McIntyre, chief scientist and co-founder of Ecovative, a company aiming to reduce our dependence on plastic and other toxic or non-decomposable materials by making biodegradable alternatives. For several years, Ecovative has been manufacturing eco-friendly packaging supplies, and has just received a grant from the Environmental Protection Agency to further develop its new product, mResin, an alternative to the harmful adhesives found in most paneling and insulation.
Ecovative products, unlike most synthetic plastics that are made from crude oil, are grown from mycelium—networks of fungal or mushroom roots. In nature, fungi break down waste, such as old leaves, dead plants, and pieces of wood, and use it to propagate. Ecovative harnesses this natural process and grows the mycelium into various shapes and structures, from pieces of furniture to packaging materials like MycoFoam, its trademarked Styrofoam substitute.
“Corona is the foe. You and I are bros. No discrimination, I’m not virus.”
African students in Shandong, China create a music video to express their best wishes for China amid the #coronavirus outbreak. #StayStrongChina
Related: Sikorsky-Boeing’s SB-1 Defiant Helicopter Prototype Impresses Leaders in Demo
Defiant strikes an intimidating silhouette with its prominent X2 technology, which features a coaxial rotor system and a large rear propeller that replaces the tail rotor found on conventional helicopters.
Sikorsky-Boeing officials said the new aircraft design will be capable of flying at speeds of more than 200 knots, or 230 miles per hour, and maneuvering like a fine-tuned sports car.
Optical technologies that can be used to modulate neuronal activity are opening up exciting possibilities for research in neuroscience and biology. Optical tools allow neuroscientists to excite and inhibit neurons or areas of the brain at will. They can thus be used to investigate the function of specific brain circuits or regions, as well as to identify new potential treatments for neurological and psychiatric diseases.
The generation of tethered azobenzene photoswitches targeted at membrane bilayers or linked to ion channels is a pioneering optical technique that could further aid the study of the human brain. This technique, however, particularly when implemented at high light intensities, can lead to a considerable increase in temperature and can thus be harmful to neurons when used repeatedly.
To overcome this limitation, researchers at the Italian Institute of Technology (IIT) in collaboration with Politecnico di Milano, have recently created a new light-sensitive azobenzene compound, dubbed Ziapin2, which can be used to build photoswitches that do not increase in temperature when irradiated with visible light. This new compound, introduced in a paper published in Nature Nanotechnology, partitions into the plasma membrane with a high stability, enabling its thinning and an increased capacitance at a steady state.
An experiment by EPFL researchers has confirmed a theory that has been used in mechanics for over half a century—despite never having been fully validated. The team could now use the theory in bolder and more innovative ways in their quest to develop ever better energy systems.
Some theories are widely used even though they have never been experimentally validated. One example is the so-called narrow groove theory, or NGT, which explains how air-lubricated bearings work in mechanical systems.
The theory was proposed in 1965 but, until recently, it had only been tested partially or indirectly. Researchers at EPFL’s Laboratory for Applied Mechanical Design (LAMD), based at Microcity in Neuch tel, have now closed a gap that has persisted in the scientific literature for over 50 years. The team has published its findings in the journal Mechanical Systems and Signal Processing.
Changing a single word can alter the way an AI program judges a job applicant or assesses a medical claim.
Superfluid helium, describable by a two-component order parameter, exhibits only the Bogolubov mode with energy $\to 0$ at long wavelengths, while a Lorentz-invariant theory with a two-component order parameter exhibits a finite energy mode at long wavelengths (the Higgs Boson), besides the above mass-less mode. The mass-less mode moves to high energies if it couples to electromagnetic fields (the Anderson-Higgs mechanism). Superconductors, on the other hand have been theoretically and experimentally shown to exhibit both modes. This occurs because the excitations in superconductors have an (approximate) particle-hole symmetry and therefore show a similarity to Lorentz-invariant theories.
