Lifeboat Foundation

Scientists at Cold Spring Harbor Laboratory (CSHL) and Stanford University have pinpointed the circuit in the brain that is responsible for sleepless nights in times of stress—and it turns out that circuit does more than make you toss and turn. Their study, done in mice, ties the same neuronal connections that trigger insomnia to stress-induced changes in the immune system, which weaken the body’s defenses against a host of threats.

The study, reported September 9, 2020, in the journal Science Advances, connects and explains two familiar problems, says CSHL Assistant Professor Jeremy Borniger. “This sort of stress-induced insomnia is well known among anybody that’s tried to get to sleep with a looming deadline or something the next day,” he says. “And in the clinical world, it’s been known for a long time that chronically stressed patients typically do worse on a variety of different treatments and across a variety of different diseases.”

Like many aspects of the body’s stress response, these effects are thought to be driven by the stress hormone cortisol. Working in the Stanford lab of Luis de Lecea, where Borniger completed a postdoctoral fellowship prior to joining CSHL, the research team found a direct connection between stress-sensitive neurons in the brain that trigger cortisol’s release and nearby neurons that promote insomnia.

Continue reading “The neurons that connect stress, insomnia, and the immune system” »

Lucid has finally fully unveiled the production version of its first car: the Lucid Air, a luxury electric sedan.

For those of you who have been following our coverage over the past few months, there won’t be many surprises since Lucid has gradually leaked the most important information. But it’s still worth diving a little deeper with all the final details.

As you get older, key genes that maintain life are no longer activated. George Church is focused on turning youth-boosting genes back on.

His company, Rejuvenate Bio, has begun clinical trials in old dogs. This will help us determine which ages of humans would best benefit. George believes they will be able to help people who are already quite old and show signs of decline. They are looking at extending absolute lifespan. Extending human lifespan will take years to get reliable results.

They have published results on three genes. Those genes already helped reverse osteoarthritis, high-fat obesity and diabetes, heart damage, and kidney disease. They will soon add cancer and neurodegenerative diseases to the list of reversible conditions.

O,.o circa 2018.

Characteristics of mysterious time crystals have been found in the most unexpected place you’d ever think to look — a compound found in fertiliser and those crystal-growing kits you can buy for kids.

That compound is monoammonium phosphate (MAP), and the physicists from Yale who made the discovery are now scratching their heads, because this raises questions about how time crystals even form in the first place.

Continue reading “Physicists Just Found Time Crystals in a Common Item You Can Buy at The Toy Store” »

A brief history of time.

GPT-3, an advanced language generator developed by OpenAI, wrote a frighteningly humanlike essay for The Guardian on how humanity shouldn’t fear AI.

Astronomers at the Keck Observatory in Hawaii say they have found the most distant galaxy yet. Its name is z8_GND_5296, and it is churning out new stars at an astounding rate. The remarkable z8_GND_5296 is believed to be about 30 billion light years away, and continues to gain distance. Scientists are hoping it can provide clues to what happened right after the Big Bang.

The Keck research team determined how far away z8_GND_5296 is by measuring precisely the redness of its light. Since the galaxy is moving away, its light waves are stretched, which makes it appear redder than it truly is. Astronomers call this phenomena redshift. This galaxy holds the redshift record at 7.51, beating the now second furthest galaxy by exactly 0.3. According to Nature, an international weekly science journal, only five known galaxies have a mathematically tested and confirmed redshift “in excess of 7.”

With regard to producing new stars, z8_GND_5296 is unusually productive. Nature says it puts out “about 330 new solar masses per year, which is which is more than a factor of 100 greater than that seen in the Milky Way.” This is even more impressive if one considers z8_GND_5296’s diminutive size. The powerhouse star-producer is only about 1–2% the size of our galaxy. Of the recorded galaxies with redshifts exceeding 7, only one other has a high star-formation rate.

Circa 2015. What if a hull of ship could have warp crystals that could slip through space time easier.

Crystals, as quantum objects typically much larger than their lattice spacing, are a counterexample to a frequent prejudice that quantum effects should not be pronounced at macroscopic distances. We propose that the Einstein theory of gravity only describes a fluid phase and that a phase transition of crystallization can occur under extreme conditions such as those inside the black hole. Such a crystal phase with lattice spacing of the order of the Planck length offers a natural mechanism for pronounced quantum-gravity effects at distances much larger than the Planck length. A resolution of the black-hole information paradox is proposed, according to which all information is stored in a crystal-phase remnant with size and mass much above the Planck scale.

Carpenter ants need endosymbiotic bacteria to guide the early development of their embryos. New work has reconstructed how this deep partnership evolved.