Lifeboat Foundation

Researchers have developed a way to modify an existing cancer drug with toxic side effects into something that is less toxic to blood platelets and more effective at removing harmful and inflammatory senescent cells, one of the reasons we age, from mice.

What are senescent cells?

As you age, increasing numbers of your cells enter into a state known as senescence. Senescent cells do not divide or support the tissues of which they are part; instead, they emit a range of potentially harmful chemical signals that encourage nearby healthy cells to enter the same senescent state. Their presence causes many problems: they reduce tissue repair, increase chronic inflammation, and can even eventually raise the risk of cancer and other age-related diseases.

Researchers investigating cribellate spiders have discovered a unique comb structure that could help inform future equipment used to manipulate nanofibers. Nanofibers have been hard to handle in a lab setting as they can stick to the equipment attempting to manipulate them, but a new study published in the journal ACS Applied Nanomaterials reveals how spiders can help us to create non-stick tools for such scenarios.

Cribellate spiders are so named because of their unique web-spinning anatomy. Most spiders have a long single spinneret that they use to produce a single thread, whereas cribellate spiders have a silk-spinning organ. This organ acts like a plate with lots of small, ever so slightly raised protrusions, each of which produces a very fine silk just a few nanometers thick. The spiders then comb these thin fibers out using a calamistrum structure on their legs, producing silk with a woolly texture. This woolly-textured silk entraps the spider’s prey, but somehow, they are able to handle it without getting caught up in their own webs.

Nanofibers are a hot area of research right now but one of the difficulties in their handling is that they commonly stick to the equipment trying to manipulate them. Lead author Anna-Christin Joel, from RWTH Aachen University, and her colleagues wondered if the solution to this frustrating problem could be found within the silk-immune spiders’ anatomy.

The Dishchii’bikoh meteorite fall in the White Mountain Apache reservation in central Arizona has given scientists a big clue to finding out where so-called LL chondrites call home. They report their results in the April 14 issue of Meteoritics and Planetary Science.

“LL chondrites are fairly common meteorites with low-oxidized and low metallic (LL) iron content,” said Peter Jenniskens, the lead author and meteor astronomer with the SETI Institute and NASA Ames Research Center. “We want to know where they originated because the damaging Chelyabinsk airburst of February 15, 2013 in Russia, was caused by a particularly large 20-meter sized LL chondrite.”

LL chondrites originate from somewhere in the asteroid belt between Mars and Jupiter, where a parent body broke up and created a family of asteroids long ago. Occasional collisions with those family members eject rocks into orbit around the Sun. When these small asteroids collide with Earth’s atmosphere, they cause a bright meteor from which pieces survive sometimes and fall on the ground as meteorites.

Circa 2017

Abilify MyCite raises new privacy concerns.

A brain-computer interface has helped a man with a severe spinal cord injury move and feel using a hand again, letting him carefully lift light objects such as a paper cup.

Article trying to answer the matter of whether we will get good meds before vaccines.

As the world waits for a vaccine, another race is underway for a COVID-19 ‘cure’. What are the most promising treatments? And could a tablet stop you getting infected in the first place?

US researchers report that they have been able to restore sensation to the hand of a research participant with a severe spinal cord injury using a brain-computer interface (BCI) system.

Florida and Georgia archaeologists have discovered the location of Fort San Antón de Carlos, home of one of the first Jesuit missions in North America. The Spanish fort was built in 1566 in the capital of the Calusa, the most powerful Native American tribe in the region, on present-day Mound Key in the center of Estero Bay on Florida’s Gulf Coast.

Archaeologists and historians have long suspected that the fort, named for the Catholic patron saint of lost things, was located on Mound Key. Researchers have been searching for concrete evidence in the area since 2013.

“Before our work, the only information we had was from Spanish documents, which suggested that the Calusa capital was on Mound Key and that Fort San Antón de Carlos was there, too,” said William Marquardt, curator emeritus of South Florida archaeology and ethnography at the Florida Museum of Natural History. “Archaeologists and historians had visited the site and collected pottery from the surface, but until we found physical evidence of the Calusa king’s house and the fort, we could not be absolutely certain.”

Thirty years ago this week — on April 24, 1990 — the Hubble Space Telescope launched into space and opened humanity’s eyes to the cosmos. Now, we reflect on how this groundbreaking instrument has changed and evolved our understanding of the universe.

Space.com spoke to retired NASA astronaut Mike Massimino, who currently serves as the senior advisor for space programs at the Intrepid Sea, Air and Space Museum, about his experiences working with the telescope and its importance to science and society.