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An arms race is unfolding in our cells: Transposons, also known as jumping genes or mobile genetic elements as they can replicate and reinsert themselves in the genome, threaten the cell’s genome integrity by triggering DNA rearrangements and causing mutations. Host cells, in turn, protect their genome using intricate defense mechanisms that stop transposons from jumping.

Now, for the first time, a retrotransposon has been caught in action inside a cell: Refining cryo-Electron Tomography (cryo-ET) techniques, scientists imaged the retrotransposon copia in the egg chambers of the fruitfly Drosophila melanogaster at sub-nanometer resolution. The paper is published in the journal Cell.

Among the international team of scientists achieving this detailed visualization are three scientists with Vienna BioCenter ties: Sven Klumpe, currently in the laboratory of Jürgen Plitzko at the Max Planck Institute of Biochemistry in Martinsried, will join IMBA and IMP to build a group as a Joint Fellow; Julius Brennecke, a Senior Group Leader at IMBA, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences; and Kirsten Senti, staff scientist in the Brennecke group. Also involved in this collaboration is the group of Martin Beck at the Max Planck Institute of Biophysics in Frankfurt.

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Researchers have developed a reactor that pulls carbon dioxide directly from the air and converts it into sustainable fuel, using sunlight as the power source.

The researchers, from the University of Cambridge, say their solar-powered reactor could be used to make fuel to power cars and planes, or the many chemical and pharmaceutical products we rely on. It could also be used to generate fuel in remote or off-grid locations.

Unlike most carbon capture technologies, the reactor developed by the Cambridge researchers does not require fossil-fuel-based power, or the transport and storage of carbon dioxide, but instead converts atmospheric CO2 into something useful using sunlight. The results are reported in the journal Nature Energy.

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In today’s AI news, CoreWeave has acquired AI developer platform Weights & Biases. According to The Information, CoreWeave spent $1.7 Billion on the transaction. Weights & Biases was valued at $1.25 Billion in 2023. The acquisition extends CoreWeave’s purpose-built cloud platform by enabling an end-to-end experience for customers, enhancing functionality for the world’s leading AI labs and enterprises to build, tune and deploy AI applications.

S Turing Award — often called the Nobel Prize of computer science — is going to Andrew Barto and Richard Sutton, the pioneers of a key approach that underlies much of today Then, a team of researchers at Zoom has developed a breakthrough technique that could dramatically reduce the cost and computational resources needed for AI systems to tackle complex reasoning problems, Chain of draft (CoD), enables large language models (LLMs) to solve problems with minimal words — using as little as 7.6% of the text required by current methods while maintaining or even improving accuracy.

And soon, all businesses will be able to use Meta’s AI to power live, 24/7 customer service that can interact with customers on behalf of businesses on Instagram, Facebook, and WhatsApp. Meta announced advancements in business AI—including the customer service AI agent that will make purchases and can respond to voice prompts from a user.

In videos, say goodbye to manual contract processing! IBM’s Brandon Swink explores how Generative AI, ECM, and Orchestration Hubs streamline document management and improve efficiency. Discover how these technologies transform your approach to complex documents.

And, in this episode of Top of Mind, Gartner Distinguished VP Analyst Daryl Plummer explores the emerging world of guardian agents — AI designed to monitor other AI. Learn how guardian agents will become critical for organizations deploying AI agents for quality control, system observation and security from rogue AI behavior.

Continue reading “CoreWeave Acquires AI Developer Platform Weights & Biases For Reported

In today’s AI news, CoreWeave has acquired AI developer platform Weights & Biases. According to The Information, CoreWeave spent $1.7 Billion on the transaction. Weights & Biases was valued at $1.25 Billion in 2023. The acquisition extends CoreWeave’s purpose-built cloud platform by enabling an end-to-end experience for customers, enhancing functionality for the world’s leading AI labs and enterprises to build, tune and deploy AI applications.

S Turing Award — often called the Nobel Prize of computer science — is going to Andrew Barto and Richard Sutton, the pioneers of a key approach that underlies much of today Then, a team of researchers at Zoom has developed a breakthrough technique that could dramatically reduce the cost and computational resources needed for AI systems to tackle complex reasoning problems, Chain of draft (CoD), enables large language models (LLMs) to solve problems with minimal words — using as little as 7.6% of the text required by current methods while maintaining or even improving accuracy.

And soon, all businesses will be able to use Meta’s AI to power live, 24/7 customer service that can interact with customers on behalf of businesses on Instagram, Facebook, and WhatsApp. Meta announced advancements in business AI—including the customer service AI agent that will make purchases and can respond to voice prompts from a user.

In videos, say goodbye to manual contract processing! IBM’s Brandon Swink explores how Generative AI, ECM, and Orchestration Hubs streamline document management and improve efficiency. Discover how these technologies transform your approach to complex documents.

And, in this episode of Top of Mind, Gartner Distinguished VP Analyst Daryl Plummer explores the emerging world of guardian agents — AI designed to monitor other AI. Learn how guardian agents will become critical for organizations deploying AI agents for quality control, system observation and security from rogue AI behavior..7 Billion” | >

Joscha Bach is a German cognitive scientist, AI researcher, and philosopher known for his work on cognitive architectures, artificial intelligence, mental representation, emotion, social modeling, multi-agent systems, and the philosophy of mind.

Links of interest:

• http://bach.ai/
• https://twitter.com/Plinz.

Steve and Joscha discuss:

Continue reading “Joscha Bach: Consciousness and AGI” | >

Main episode with Michael Levin (June 2024): https://youtu.be/c8iFtaltX-s?list=PLZ7ikzmc6zlN6E8KrxcYCWQIHg2tfkqvR

Become a YouTube Member Here:
https://www.youtube.com/channel/UCdWIQh9DGG6uhJk8eyIFl1w/join.

Listen on Spotify: https://open.spotify.com/show/4gL14b92xAErofYQA7bU4e.

Join TOEmail at https://www.curtjaimungal.org.

Continue reading “Universal Mind, Synchronicity, Bernardo Kastrup, and God | Top Biologist Michael Levin” | >

Dr. Michael Levin’s groundbreaking research redefines intelligence, agency, and selfhood, showing that it exists not just in brains but across all levels of biological systems—cells, organs, and entire organisms. Through his concept of the “morphogenetic code,” Levin reveals that bioelectric signals, not just DNA, guide cellular organization and behavior, enabling profound regenerative breakthroughs like limb regrowth and functional organ creation. His work extends into philosophy, reshaping how we view alien life, selfhood, and even the nature of existence by framing life as an emergent property of interconnected intelligences. Levin envisions tools like an “anatomical compiler” to revolutionize medicine and challenges us to rethink life, intelligence, and the cosmos, solidifying his place as one of the most important living scientists.

Deep Thinkers, Check This: https://www.skool.com/yoda/about.

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In human engineering, we design systems to be predictable and controlled. By contrast, nature thrives on systems where simple rules generate rich, emergent complexity. The computational nature of the universe explains how simplicity can generate the complexity we see in natural phenomena. Imagine being able to understand everything about the universe and solve all its mysteries by a computational approach that uses very simple rules. Instead of being limited to mathematical equations, using very basic computational rules, we might be able to figure out and describe everything in the universe, like what happened at the very beginning? What is energy? What’s the nature of dark matter? Is traveling faster than light possible? What is consciousness? Is there free will? How can we unify different theories of physics into one ultimate theory of everything?

This paradigm goes against the traditional notion that complexity in nature must arise from complicated origins. It claims that simplicity in fundamental rules can produce astonishing complexity in behavior. Entering the Wolfram’s physics project: The computational universe!

Thousands of hours have been dedicated to the creation of this video. Producing another episode of this caliber would be difficult without your help. If you would like to see more, please consider supporting me on / disculogic, or via PayPal for a one-time donation at https://paypal.me/Disculogic.

Chapters:

Continue reading “Wolfram’s Theory of Everything: The Universe Is a Giant Computer” | >

ETH researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin. One day, researchers want to use switches of this kind to trigger cell therapies for various metabolic diseases.

The body regulates its metabolism precisely and continuously, with specialized cells in the pancreas constantly monitoring the amount of sugar in the blood, for example. When this blood sugar level increases after a meal, the body sets a signal cascade in motion in order to bring it back down.

In people suffering from diabetes, this regulatory mechanism no longer works exactly as it should. Those affected therefore have too much sugar in their blood and need to measure their blood sugar level and inject themselves with insulin in order to regulate it. This is a relatively imprecise approach compared to the body’s own mechanism.

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