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“TECLA (an acronym which stands for “Technology and Clay”) is a habitat consisting of two interconnected housing units, each covered by a semi-spherical dome. The units have been built using multiple Crane Wasp printing units operating simultaneously. Crane WASP is defined by the manufacturer as “a collaborative 3D printing system capable of printing houses” and can print various materials — such as earth-based materials, concrete mortar, and geopolymers — with a maximum speed of 300 mm/s and a maximum printing area of 50 sqm per unit. The design of the habitat features two or more “cocoon-like” housing units, whose shape vaguely resembles that of a sea urchin, in which structure, insulation, and finishes coincide. The thick raw earth walls of the units have a hollow structure consisting of several clay “waves”, which makes them at the same time relatively lightweight, resistant, and highly insulating. About 200 printing hours are required to build each unit, which consists of 350 clay layers, each 12 mm thick.”


Designed by Mario Cucinella and build by WASP, TECLA is a prototype house near Ravenna, Italy, made by 3D-printing a material based on locally-sourced clay.

The Hallmarks of Aging are well established, but what is less discussed is the impact of microbes. Viruses, including SARS-CoV-2 and HSV-1 cause mitochondrial dysfunction-more specifically, they cause mitochondria to release some of their DNA, which triggers antiviral immunity. When considering that blood levels of mitochondrial DNA increase during aging, is aging characterized by an increased viral burden?

Paper links:
Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19
pathogenesis: https://pubmed.ncbi.nlm.nih.gov/32510973/

Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm‐aging”: https://onlinelibrary.wiley.com/doi/full/10.1002/eji.

National Seroprevalence and Trends in Herpes Simplex Virus Type 1 in the United States, 1976–1994: https://pubmed.ncbi.nlm.nih.gov/15608591/

This is the SECOND PART of the interview with Harold Katcher in Modern Healthspan YouTube channel.


Dr. Harold Katcher is a professor of Biology at the University of Maryland. He has been a pioneer in the field of cancer research, in the development of modern aspects of gene hunting and sequencing. He carries expertise in bioinformatics, chronobiology, and biotechnology. Dr. Katcher is currently working in the capacity of Chief Technical Officer at Nugenics Research exploring rejuvenation treatments in mammals.
In May 2020 there was a paper published on biorxiv about the rejuvenation of rats by over 50%. We did a review of the paper which you can find linked to above. In this interview series we talk with Dr. Harold Katcher, one of the main authors of the paper about the experiment, the steps to get validation, commercialization and how the results fit into his theories of aging.

In this video we talk about how the results from the experiment will be validated in two third party labs. One of which will use Rhesus monkeys and the other, under Dr. Greg Fahy, will use dogs.

But the human eye can only see so much, even with the help of a microscope; despite embryologists’ efforts to select the “best” embryo, success rates are still relatively low. “Many decisions are based on gut feeling or personal experience,” said Embryonics founder and CEO Yael Gold-Zamir. “Even if you go to the same IVF center, two experts can give you different opinions on the same embryo.”

This is where Embryonics’ technology comes in. They used 8,789 time-lapse videos of developing embryos to train an algorithm that predicts the likelihood of successful embryo implantation. A little less than half of the embryos from the dataset were graded by embryologists, and implantation data was integrated when it was available (as a binary “successful” or “failed” metric).

The algorithm uses geometric deep learning, a technique that takes a traditional convolutional neural network—which filters input data to create maps of its features, and is most commonly used for image recognition—and applies it to more complex data like 3D objects and graphs. Within days after fertilization, the embryo is still at the blastocyst stage, essentially a microscopic clump of just 200–300 cells; the algorithm uses this deep learning technique to spot and identify patterns in embryo development that human embryologists either wouldn’t see at all, or would require massive collation of data to validate.


The human eye can only see so much, and despite embryologists’ efforts to select the “best” embryo, IVF success rates are still relatively low.

Did you know, getting a bit cold from time to time can help you get fitter, live longer, reduce pain and discomfort and help you concentrate and feel great?
Whether it is cold showers, ice baths, swimming in open water or trying out cryotherapy, enduring the cold is becoming increasingly popular as a way to hack your body as an aid to longevity and a good health span.
And for a good reason.
It effects metabolism, heart rate, blood pressure and many biomarkers.
It improves pain tolerance and levels, your mood and energy levels.
It effects mitochondrial biogenesis and brown fat stores, even beiging previously white adipose tissue.
In fact, there are hardly any systems left untouched.
But it does have side effects as well, especially for those who have health issues, but they also have the most to gain.
If you want to get more detail then check out this video where I go into more depth looking at the subject and discuss the studies that have been done to assess the effects.
Have a great day.


In Cold Showers Pros And Cons — And Other Cold Therapies, I will be looking at the good, and the bad, when it comes to embracing cold therapies from cold water swimming and ice baths, through to cold showers and cryotherapy.

What are they all about?