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Using intuition, educated guesswork and computer simulations, condensed matter physicists have become better at figuring out which quasiparticles are theoretically possible. Meanwhile in the lab, as physicists push novel materials to new extremes, the quasiparticle zoo has grown quickly and become more and more exotic. “It really is a towering intellectual achievement,” said Natelson.

Recent discoveries include pi-tons, immovable fractons and warped wrinklons. “We now think about quasiparticles with properties that we never really dreamt of before,” said Steve Simon, a theoretical condensed matter physicist at the University of Oxford.

Here are a few of the most curious and potentially useful quasiparticles.

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The New York Times Apr 09, 2021 17:29:04 IST

Evidence is mounting that a tiny subatomic particle seems to be disobeying the known laws of physics, scientists announced Wednesday, a finding that would open a vast and tantalizing hole in our understanding of the universe. The result, physicists say, suggests that there are forms of matter and energy vital to the nature and evolution of the cosmos that are not yet known to science.

“This is our Mars rover landing moment,” said Chris Polly, a physicist at the Fermi National Accelerator Laboratory, or Fermilab, in Batavia, Illinois, who has been working toward this finding for most of his career.

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Wildlife Care And Combating Emerging Zoonotic Diseases — Dr. Suzan Murray, D.V.M., D.A.C.Z.M. Smithsonian’s National Zoo and Conservation Biology Institute, Program Director, Global Health Program.

Dr. Suzan Murray, D.V.M., D.A.C.Z.M. is a board-certified zoo veterinarian at the Smithsonian Conservation Biology Institute (SCBI) and serves as both the Program Director of the Global Health Program and as SCBI’s chief wildlife veterinary medical officer.

Dr. Murray leads an interdisciplinary team engaged in worldwide efforts to address health issues in endangered wildlife and combat emerging infectious diseases of global significance, including zoonotic diseases.

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New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.

Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to organisms’ DNA. While the system could potentially be useful in treating a variety of diseases, CRISPR-Cas9 editing involves cutting DNA strands, leading to permanent changes to the cell’s genetic material.

Now, in a paper published online in Cell on April 9, researchers describe a new gene editing technology called CRISPRoff that allows researchers to control gene expression with high specificity while leaving the sequence of the DNA unchanged. Designed by Whitehead Institute Member Jonathan Weissman, University of California San Francisco assistant professor Luke Gilbert, Weissman lab postdoc James Nuñez and collaborators, the method is stable enough to be inherited through hundreds of cell divisions, and is also fully reversible.

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