Toggle light / dark theme

Rocket builder ABL Space signed a long-term agreement for multiple launches with Lockheed Martin, agreeing to provide the defense giant with as many as 58 rockets through the end of the decade.

Lockheed Martin will buy up to 26 of ABL’s RS1 rockets through 2025, with an option for up to 32 additional launches through 2029, ABL announced on Monday.

“Having this assured access to space will accelerate our ability to demonstrate the spacecraft and associated payload technologies we are developing to the meet the future mission needs for our customers,” Lockheed Martin Space executive vice president Rick Ambrose said in a press release.

There’s an additional reason why international agreement and co-operation in the outer space domain is crucial: the peaceful use of outer space, as required by the Outer Space Treaty.

In October 2020, eight countries signed a NASA-led initiative called the Artemis Accords. These included the United States, Canada, Australia and Luxembourg. Notably absent were Russia and China, who have since agreed to collaborate with each other on space initiatives.

Legal issues about the ownership of space resources must urgently be addressed to avoid space wars over natural resources between superpowers like the U.S., Russia and China. This includes the legal status of the Artemis Accords. Ideally, it should be done before space mining starts.

If we look at the mortality tables, it can explain why reversing aging damage reversal has to work very well for people to live very long lives.

Let us imagine that we are able to reverse aging damage so that someone is 65 or older has the same amount of aging as someone who is 65. This means for an average American man, then half of those people will still be dead by the time they have reached 95 years of age. This is because 1.6% of them are dying every year in the 65-year-old condition. Also, only 80% of them have survived from birth to the age of 65.

Asian American women in New Jersey live to a life expectancy of 93. Half of them reach the age of 93. Antiaging that reverses the aging damage every year for men so that they never get worse physically than when they are 65, get them to a life expectancy that is just beyond what Asian American women in New Jersey already achieve.

April 6 — 7, 2021, 9:00am — 5:00pm EST

MAKING IN SPACE
FROM MINING TO MANUFACTURING
As humanity expands into space and unlocks the incalculable abundance of the CisLunar Econosphere, Orbital Manufacturing is a necessary first step.

Here on Earth, settlements emerged around concentrations of natural resources: rivers, forests, ores, harbors, fertile fields. Roads then developed between the resources and settlements, and towns grew. Resource extraction (mining) and resource optimization (manufacturing) evolved. Eventually, specialization led to local, regional, and national competitive advantages. With growth speeding the process, communities and people prospered!

This month, we’ll explore the evolution of orbital manufacturing, its technological and production capabilities on orbit, and the financial and industrial impacts on the United States.


“Our new data suggest that the upregulation of Neuregulin-responsive genes in animals with severely repetitive behaviors reflects gene changes in the striosomal neurons that control the release of dopamine,” Crittenden explains. “Dopamine can directly impact whether an animal repeats an action or explores new actions, so our study highlights a potential role for a striosomal circuit in controlling action-selection in health and in neuropsychiatric disease.”


Graybiel lab identifies genes linked to abnormal repetitive behaviors often seen in models of addiction and schizophrenia.

Extreme repetitive behaviors such as hand-flapping, body-rocking, skin-picking, and sniffing are common to a number of brain disorders including autism, schizophrenia, Huntington’s disease, and drug addiction. These behaviors, termed stereotypies, are also apparent in animal models of drug addiction and autism.

In a new study published in the European Journal of Neuroscience, researchers at the McGovern Institute for Brain Research have identified genes that are activated in the brain prior to the initiation of these severe repetitive behaviors.

For first time, fibroblast-derived model of early embryo will allow extensive study into causes of very early miscarriage and effects of toxins and drugs on early development.

In a discovery that will revolutionize research into the causes of early miscarriage, infertility and the study of early human development — an international team of scientists led by Monash University in Melbourne, Australia has generated a model of a human embryo from skin cells.

The team, led by Professor Jose Polo, has successfully reprogrammed these fibroblasts or skin cells into a 3-dimensional cellular structure that is morphologically and molecularly similar to human blastocysts. Called iBlastoids, these can be used to model the biology of early human embryos in the laboratory.

A patient with a genetic form of childhood blindness gained vision, which lasted more than a year, after receiving a single injection of an experimental RNA therapy into the eye.

The gene editing research was conducted at the Perelman School of Medicine in the University of Pennsylvania. Results of the case, detailed in a paper published April 1 in Nature Medicine, show that the treatment led to marked changes at the fovea, the most important point of human central vision.

In the international clinical trial, participants received an intraocular injection of an antisense oligonucleotide called sepofarsen. This short RNA molecule works by increasing normal CEP290 protein levels in the eye’s photoreceptors and improving retinal function under day vision conditions.