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Blog – Page 6688

A lava flow from Hawaii’s Kilauea Volcano enters the ocean near Isaac Hale Beach Park on August 5, 2018. The volcano’s 2018 eruption was its largest in over 200 years. Credit: USGS

Scientists have figured out what triggers large-scale volcanic eruptions and what conditions likely lead to them.

Hawaii’s Kilauea is one of the most active volcanoes in the world. Because of this and its relative ease of accessibility, it is also among the most heavily outfitted with monitoring equipment – instruments that measure and record everything from earthquakes and ground movement to lava volume and advancement.

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Scientists dramatically enhance the achievable resolution at free-electron lasers with a new technique.

Hard X-ray free-electron lasers (XFELs) have delivered intense, ultrashort X-ray pulses for over a decade. One of the most promising applications of XFELs is in biology, where researchers can capture images down to the atomic scale even before the radiation damage destroys the sample. In physics and chemistry, these X-rays can also shed light on the fastest processes occurring in nature with a shutter speed lasting only one femtosecond – equivalent to a millionth of a billionth of a second.

However, on these minuscule timescales, it is extremely difficult to synchronize the X-ray pulse that sparks a reaction in the sample on the one hand and the laser pulse which ‘observes’ it on the other. This problem is called timing jitter, and it is a major hurdle in ongoing efforts to perform time-resolved experiments at XFELs with ever-shorter resolution.

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“Gene editing offers unique opportunities to make food production more sustainable and to further improve the quality, but also the safety, of food. With the help of these new molecular tools, more robust plants can be developed that deliver high yields for high-quality nutrition, even with less fertiliser,” says co-author Stephan Clemens, Professor of Plant Physiology at the University of Bayreuth and founding Dean of the new Faculty of Life Sciences: Food, Nutrition & Health on the Kulmbach campus.

For more sustainability on a global level, EU legislation should be changed to allow the use of gene editing in organic farming. This is what an international research team involving the Universities of Bayreuth and Göttingen demands in a paper published in the journal “Trends in Plant Science”.

In May 2020, the EU Commission presented its “Farm-to-Fork” strategy, which is part of the “European Green Deal”. The aim is to make European agriculture and its food system more sustainable. In particular, the proportion of organic farming in the EU’s total agricultural land is to be increased to 25 percent by 2030. However, if current EU legislation remains in place, this increase will by no means guarantee more sustainability, as the current study by scientists from Bayreuth, Göttingen, Düsseldorf, Heidelberg, Wageningen, Alnarp, and Berkeley shows.

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Large swaths of U.S. military land are covered with munitions components, including the explosive chemical RDX. This molecule is toxic to people and can cause cancer. It also doesn’t naturally break down and can contaminate groundwater. Now researchers have genetically engineered a grass commonly used to fight soil erosion so that it can remove RDX from the soil, according to a new paper published May 3 in Nature Biotechnology.

A team, which includes researchers from the University of Washington, demonstrated that over the course of three years, a genetically engineered switchgrass could break down an explosive chemical in…

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At Rehab, a nurse explained to me that my swallowing problem was caused by weak muscles in the esophageal sphincter. That information stimulated me to create my own therapy for the esophageal sphincter. I wrote out the transcript for the therapy, and a lady named Collette read it into a recorder. I listen to the recording several times a day. My swallowing problems resulted in a feeding being inserted up my nose. The therapy makes it possible for me to eat oatmeal, grits, eggs, pasta & beef, and corn flakes. After passing the swallowing test last Friday, the Speech Pathologist sent me to the Emergency Room, where they pulled the feeding tube from my nose.

Dysphagia refers to the difficulty in swallowing after a stroke. It is a problem that can be easily managed with proper medical care.

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Papers referenced in the video:

Remnant Cholesterol and Atherosclerotic Cardiovascular Disease Risk:
https://www.jacc.org/doi/10.1016/j.jacc.2020.10.

The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling:
https://www.sciencedirect.com/science/article/pii/S0753332220309781

Joint distribution of lipoprotein cholesterol classes. The Framingham study:

Continue reading “VLDL Increases During Aging, And Is Associated With Adverse Cardiovascular Outcomes” | >

Quantum entanglement occurs when two separate entities become strongly linked in a way that cannot be explained by classical physics; it is a powerful resource in quantum communication protocols and advanced technologies that aim to exploit the enhanced capabilities of quantum systems. To date, entanglement has generally been limited to microscopic quantum units such as pairs or multiples of single ions, atoms, photons, and so on. Kotler et al. and Mercier de Lépinay et al. demonstrate the ability to extend quantum entanglement to massive macroscopic systems (see the Perspective by Lau and Clerk). Entanglement of two mechanical oscillators on such a large length and mass scale is expected to find widespread use in both applications and fundamental physics to probe the boundary between the classical and quantum worlds.

Science, this issue p. 622, p. 625; see also p. 570

Quantum entanglement of mechanical systems emerges when distinct objects move with such a high degree of correlation that they can no longer be described separately. Although quantum mechanics presumably applies to objects of all sizes, directly observing entanglement becomes challenging as masses increase, requiring measurement and control with a vanishingly small error. Here, using pulsed electromechanics, we deterministically entangle two mechanical drumheads with masses of 70 picograms. Through nearly quantum-limited measurements of the position and momentum quadratures of both drums, we perform quantum state tomography and thereby directly observe entanglement. Such entangled macroscopic systems are poised to serve in fundamental tests of quantum mechanics, enable sensing beyond the standard quantum limit, and function as long-lived nodes of future quantum networks.

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Humans are distinguished from other species by several aspects of cognition. While much comparative evolutionary neuroscience has focused on the neocortex, increasing recognition of the cerebellum’s role in cognition and motor processing has inspired considerable new research. Comparative molecular studies, however, generally continue to focus on the neocortex. We sought to characterize potential genetic regulatory traits distinguishing the human cerebellum by undertaking genome-wide epigenetic profiling of the lateral cerebellum, and compared this to the prefrontal cortex of humans, chimpanzees, and rhesus macaque monkeys. We found that humans showed greater differential CpG methylation–an epigenetic modification of DNA that can reflect past or present gene expression–in the cerebellum than the prefrontal cortex, highlighting the importance of this structure in human brain evolution. Humans also specifically show methylation differences at genes involved in neurodevelopment, neuroinflammation, synaptic plasticity, and lipid metabolism. These differences are relevant for understanding processes specific to humans, such as extensive plasticity, as well as pronounced and prevalent neurodegenerative conditions associated with aging.

Citation: Guevara EE, Hopkins WD, Hof PR, Ely JJ, Bradley BJ, Sherwood CC (2021) Comparative analysis reveals distinctive epigenetic features of the human cerebellum. PLoS Genet 17: e1009506. https://doi.org/10.1371/journal.pgen.

Editor: Takashi Gojobori, National Institute of Genetics, JAPAN.

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