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A study of gene activity in the brain’s hippocampus, led by UT Southwestern researchers, has identified marked differences between the region’s anterior and posterior portions. The findings, published today in Neuron, could shed light on a variety of brain disorders that involve the hippocampus and may eventually help lead to new, targeted treatments.

“These new data reveal molecular-level differences that allow us to view the anterior and posterior hippocampus in a whole new way,” says study leader Genevieve Konopka, Ph.D., associate professor of neuroscience at UTSW.

She and study co-leader Bradley C. Lega, M.D., associate professor of neurological surgery, neurology, and psychiatry, explain that the human hippocampus is typically considered a uniform structure with key roles in memory, spatial navigation, and regulation of emotions. However, some research has suggested that the two ends of the hippocampus—the anterior, which points downward toward the face, and the posterior, which points upward toward the back of the head—take on different jobs.

Scientists from the Cluster of Excellence ct.qmat—Complexity and Topology in Quantum Matter have developed a new understanding of how electrons behave in strong magnetic fields. Their results explain measurements of electric currents in three-dimensional materials that signal a quantum Hall effect—a phenomenon thus far only associated with two-dimensional metals. This new 3D effect can be the foundation for topological quantum phenomena, which are believed to be particularly robust and therefore promising candidates for extremely powerful quantum technologies. These results have just been published in the scientific journal Nature Communications.

Dr. Tobias Meng and Dr. Johannes Gooth are early career researchers in the Würzburg-Dresdner Cluster of Excellence ct.qmat that researches topological quantum materials since 2019. They could hardly believe the findings of a recent publication in Nature claiming that electrons in the topological zirconium pentatelluride (ZrTe5) move only in two-dimensional planes, despite the fact that the material is three-dimensional. Meng and Gooth therefore started their own research and experiments on the material ZrTe5. Meng from the Technische Universität Dresden (TUD) developed the theoretical model, Gooth from the Max Planck Institute for Chemical Physics of Solids designed the experiments. Seven measurements with different techniques always lead to the same conclusion.

Scientists have examined the performance of pure boron, boron carbide, high-density carbon and boron nitride ablators—the material that surrounds a fusion fuel and couples with the laser or hohlraum radiation in an experiment—in the polar direct drive exploding pusher (PDXP) platform, which is used at the National Ignition Facility (NIF). The platform uses the polar direct drive configuration to drive high ion temperatures in a room-temperature capsule and has potential applications for plasma physics studies and as a neutron source.

The key findings of the work, featured in High Energy Density Physics, show that these alternate ablators do not improve the symmetry of the PDXP implosion, according to lead author Heather Whitley, associate program director for High Energy Density Science in the Fundamental Weapon Physics section at Lawrence Livermore National Laboratory (LLNL).

“While our simulations predict that the platform is not amenable to the electron-ion coupling measurements due to a lack of implosion symmetry, the alternate materials do enable better coupling between the laser and capsule,” she said. “We plan to test those predicted impacts on future experiments.”

While the remaining supersonic contenders duke it out to bring faster jets to market, private jet operators are doing their best to address the business traveler’s appetite for speed with aircraft that are as close to the sound barrier as they can be without actually breaking it, which poses all kinds of environmental issues.


With the news that supersonic planemaker Aerion has unexpectedly folded, is the dream of a successor to Concorde running out of fuel?

In the myofiber-specific model, they found that adding the Yamanaka factors accelerated muscle regeneration in mice by reducing the levels of a protein called Wnt4 in the niche, which in turn activated the satellite cells.


Salk research reveals clues about molecular changes underlying muscle loss tied to aging.

One of the many effects of aging is loss of muscle mass, which contributes to disability in older people. To counter this loss, scientists at the Salk Institute are studying ways to accelerate the regeneration of muscle tissue, using a combination of molecular compounds that are commonly used in stem-cell research.

In a study published on May 25, 2021, in Nature Communications, the investigators showed that using these compounds increased the regeneration of muscle cells in mice by activating the precursors of muscle cells, called myogenic progenitors. Although more work is needed before this approach can be applied in humans, the research provides insight into the underlying mechanisms related to muscle regeneration and growth and could one day help athletes as well as aging adults regenerate tissue more effectively.

A new map of dark matter made using artificial intelligence reveals hidden filaments of the invisible stuff bridging galaxies.

The map focuses on the local universe — the neighborhood surrounding the Milky Way. Despite being close by, the local universe is difficult to map because it’s chock full of complex structures made of visible matter, said Donghui Jeong, an astrophysicist at Pennsylvania State University and the lead author of the new research.

“We have to reverse engineer to know where dark matter is by looking at galaxies,” Jeong told Live Science.

We know dark matter exists because we can observe its effects on all the stuff that’s swirling around in the universe. Scientists estimate that about 27% of the universe is made of dark matter (68% is dark energy, and the last 5% is ordinary matter and energy). The questions on everyone’s mind: Where exactly is all that elusive stuff located? And how is it distributed throughout the universe?

An international project of over 400 scientists called the Dark Energy Survey is working on answering them. It has just released the largest and most detailed map of dark matter in the universe—with some unexpected findings that don’t yet neatly align with ideas in physics that date all the way back to Albert Einstein and his theory of general relativity.