Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 6456

After stacking the stages of the Space Launch System (SLS) rocket for NASA’s Artemis 1 mission in June and July, EGS and TOSC powered up the Core Stage for the first time in the Vehicle Assembly Building (VAB) at the Kennedy Space Center (KSC) in Florida on August 6. The initial power up was a significant milestone in pre-launch processing, marking the beginning of the systematic checkouts of the vehicle and ground systems that will be used for the first launch on Artemis 1.

Just prior to powering up the Core Stage, the four umbilicals that connect ground services from the Mobile Launcher were attached to quick disconnect plates on the stage’s three major equipment bays: the forward skirt, intertank, and engine section. The Integrated Operations team of EGS and Jacobs and the SLS prime contractors are working almost around clock in the VAB to get through all the installations, checkouts, and special tests in time for a launch no earlier than the end of 2,021 but more likely in early 2022.

Read more | >

Probiotics help prevent some infections in this study.

However, relatively little is known about the mechanisms used by Listeria to cross the intestinal barrier. Understanding more about the way Listeria spreads around the body would allow us to consider strategies for preventing infection in high-risk populations.

At Purdue University in Indiana, USA, Professor Arun Bhunia, Dr Rishi Drolia and the team are researching the mechanisms of pathogenesis (development of disease) used by Listeria to enter the bloodstream.

Read more | >

Seeing the environmental crises rising particularly because of the construction sector, more conscious choices regarding building materials need to be considered. Since the beginning of our craft, architects and constructors have been trying to utilize natural materials in buildings—either used in their raw form, like bamboo, or processed and incorporated into different materials. Hempcrete is one type of concrete incorporating natural materials; it is energy-saving and durable.

Read more | >

Dean’s appearance at TED comes during a time when critics—including current Google employees —are calling for greater scrutiny over big tech’s control over the world’s AI systems. Among those critics was one who spoke right after Dean at TED. Coder Xiaowei R. Wang, creative director of the indie tech magazine Logic, argued for community-led innovations. “Within AI there is only a case for optimism if people and communities can make the case themselves, instead of people like Jeff Dean and companies like Google making the case for them, while shutting down the communities [that] AI for Good is supposed to help,” she said. (AI for Good is a movement that seeks to orient machine learning toward solving the world’s most pressing social equity problems.)

TED curator Chris Andersen and Greg Brockman, co-founder of the AI ethics research group Open AI, also wrestled with the unintended consequences of powerful machine learning systems at the end of the conference. Brockman described a scenario in which humans serve as moral guides to AI. “We can teach the system the values we want, as we would a child,” he said. “It’s an important but subtle point. I think you do need the system to learn a model of the world. If you’re teaching a child, they need to learn what good and bad is.”

There also is room for some gatekeeping to be done once the machines have been taught, Anderson suggested. “One of the key issues to keeping this thing on track is to very carefully pick the people who look at the output of these unsupervised learning systems,” he said.

Read more | >

Since receiving a $25 million grant in 2,019 to become the first National Science Foundation (NSF) Quantum Foundry, UC Santa Barbara researchers affiliated with the foundry have been working to develop materials that can enable quantum information-based technologies for such applications as quantum computing, communications, sensing, and simulation.

They may have done it.

In a new paper, published in the journal Nature Materials, foundry co-director and UCSB professor Stephen Wilson and multiple co-authors, including key collaborators at Princeton University, study a new material developed in the Quantum Foundry as a candidate superconductor—a material in which electrical resistance disappears and magnetic fields are expelled—that could be useful in future quantum computation.

Read more | >

Researchers from the group of Hans Clevers (Hubrecht Institute) corrected mutations that cause cystic fibrosis in cultured human stem cells. In collaboration with the UMC Utrecht and Oncode Institute, they used a technique called prime editing to replace the ‘faulty’ piece of DNA with a healthy piece. The study, published in Life Science Alliance on August 9 shows that prime editing is safer than the conventional CRISPR/Cas9 technique. “We have for the first time demonstrated that this technique really works and can be safely applied in human stem cells to correct cystic fibrosis.”

Cystic fibrosis (CF) is one of the most prevalent genetic diseases worldwide and has grave consequences for the patient. The mucus in the lungs, throat and intestines is sticky and thick, which causes blockages in organs. Although treatments are available to dilute the mucus and prevent inflammations, CF is not yet curable. However, a new study from the group of Hans Clevers (Hubrecht Institute) in collaboration with the UMC Utrecht and Oncode Institute offers new hope.

Correcting CF mutations

The researchers succeeded in correcting the that cause CF in human intestinal organoids. These organoids, also called mini-organs, are tiny 3D structures that mimic the intestinal function of patients with CF. They were previously developed by the same research group from stem cells of patients with CF and stored in a biobank in Utrecht. For the study, published in Life Science Alliance, a technique named prime editing was used to replace the piece of mutated DNA that causes CF with a healthy piece of DNA in these organoids.

Read more | >