Jul 6, 2021
Common Mechanism Underlies Some Behavioral Traits Seen in Autism and Schizophrenia
Posted by Jason Blain in categories: biotech/medical, genetics, robotics/AI
The researchers also showed that they could restore normal cognitive function in mice with these genetic mutations by artificially turning down hyperactivity in neurons of the AD thalamus. The approach they used, chemogenetics, is not yet approved for use in humans. However, it may be possible to target this circuit in other ways, the researchers say.
Summary: Certain genes that are mutated or missing in those with schizophrenia and autism cause similar dysfunction in neural networks within the thalamus.
Source: MIT