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Jun 3, 2020

Lab-grown mini-livers bring us closer to an organ donor-free future

Posted by in categories: biotech/medical, futurism

In a fascinating new study, scientists created fully-functional mini-livers out of human skin cells, then successfully transplanted them into rats.

The research is a proof-of-concept for potentially revolutionary technology and provides a glimpse of an organ donor free future.

Jun 3, 2020

Fauci: Moderna COVID-19 Phase III Trial to Begin in July with 30,000 Patients

Posted by in category: biotech/medical

“That’s very early,” Anna Durbin, a vaccine researcher at Johns Hopkins University, told STAT. “We don’t know if those antibodies are durable.”

The Moderna press release also indicated that the antibody levels observed were equal to or greater in the 100 ug dose than was seen in patients who recovered from COVID-19. There’s not much context here, because studies on recovered COVID-19 patients have shown a range that is potentially influenced by the severity of the disease. For example, John “Jack” Rose, a Yale University vaccine researcher told STAT about a study in China demonstrating that in 175 recovered COVID-19 patients, 10 had no detectable neutralizing antibodies, while others had very high antibody levels.

Of the Phase III trial, Fauci indicated that the majority of trial participants will be between the ages of 18 and 55, but will include elderly Americans that are most at risk of serious illness from COVID-19.

Jun 3, 2020

World War 3 fears: Russia plans more than 100 military drills this year

Posted by in categories: existential risks, military

RUSSIA plans to hold more than 100 military drill this summer as Vladimir Putin ramps up his nation’s war readiness.

Jun 3, 2020

73 Years After Its Debut, The Doomsday Clock Is 100 Seconds From Midnight

Posted by in categories: existential risks, military, nuclear energy

73 years ago, the same scientists who had helped to begin the atomic age set a “doomsday clock” for humanity. It first appeared on the cover of the June 1947 issue of the Bulletin of the Atomic Scientists as a dire warning about the nuclear rivalry between the U.S. and the Soviet Union. At that moment, the Bulletin estimated that we stood at about 7 minutes to midnight, which represented nuclear apocalypse.

The Doomsday Clock wasn’t – and still isn’t – a precise countdown to the end of all things. It’s a metaphor for how dangerous the global situation seems to be at a given moment, in the very well-informed but also subjective opinion of the Bulletin’s board of directors. In June 1947, things looked dire. The U.S. had dropped a pair of atomic bombs on Japan less than two years before; when the Bulletin of the Atomic Scientists first published the Doomsday Clock image, researchers were still studying the aftermath of those bombs. Meanwhile, the Soviet Union was hard at work on its own atomic program, and was just a couple of years away from testing its first atomic bomb in 1949.

Through the Cold War and in the decades since, the clock’s minute hand has moved about two dozen times. In September 1953, it stood at two minutes to midnight, following Russia’s August 1953 hydrogen bomb test – which in turn had followed a U.S. hydrogen bomb test in November 1952. Those tests meant the two feuding superpowers each had much more powerful new weapons with which to destroy each other; the tests also heightened the sense of life-or-death competition that made it more likely that someone would decide to use those terrible new bombs.

Jun 3, 2020

Tesla owner ‘charges’ Model 3 with homemade solar panel trailer

Posted by in categories: energy, sustainability, transportation

A Tesla owner has demonstrated a rather novel way to charge his Model 3. In a recent video, Sean Callaghan of the ItsYeBoi YouTube channel opted to use a series of off-the-shelf solar panel sheets onto a towable trailer to create a mobile charging unit for his all-electric sedan.

Callaghan planned to use only the sun and the solar sheets purchased from e-commerce platform Wish to charge his Model 3. The solar panel sheets would collect energy from the sun and transfer it to a control panel. The control panels were connected to batteries that would hold the energy—the batteries connected to an inverter, which would then charge the Tesla Model 3.

The entire assembly would provide the Model 3 with about 800 watts of energy on a completely sunny day. However, Callaghan shot the video when weather was overcast, so the entire solar panel trailer build only managed to provide around 300 watts throughout the YouTube host’s test.

Jun 3, 2020

Handheld UV Light Devices That Kill COVID-19, Other Viruses May Soon Be As Common As Phone, Keys

Posted by in categories: biotech/medical, chemistry, mobile phones

UNIVERSITY PARK, Pa. — Phone, keys, wallet…ultraviolet light device. Just in case you wanted yet another item to carry around all day, researchers say that portable, handheld COVID-19 killing ultraviolet light devices may be a reality in the future. These gadgets would emit high-intensity ultraviolet light and quickly disinfect targeted areas.

There are two main ways to clean and remove bacteria and viruses from a given surface: chemicals and ultraviolet (UV) radiation exposure. UV radiation between 200 and 300 nanometers can effectively kill a virus and stop it from replicating itself. Obviously, devices emitting UV rays would come in handy these days due to COVID-19, but as of now such devices require an expensive, bulky mercury-containing gas discharge lamp with a short battery life.

The study’s authors, however, believe that much more portable, longer lasting, energy efficient, and environmentally friendly UV light emitting diodes can be developed. The necessary LEDs already exist, but the process has been complicated by the fact that electrode materials must also be transparent.

Jun 3, 2020

Scientists have discovered the world’s oldest known land animal. It’s 425 million years old

Posted by in category: futurism

It’s older than the dinosaurs.

Jun 3, 2020

OpenAI Announces GPT-3 AI Language Model with 175 Billion Parameters

Posted by in category: robotics/AI

A team of researchers from OpenAI recently published a paper describing GPT-3, a deep-learning model for natural-language with 175 billion parameters, 100x more than the previous version, GPT-2. The model is pre-trained on nearly half a trillion words and achieves state-of-the-art performance on several NLP benchmarks without fine-tuning.

In paper published on arXiv, a team of over 30 co-authors described the model and several experiments. The researchers’ goal was to produce an NLP system that performs well on a variety of tasks with little or no fine-tuning, and previous work had indicated that larger models might be the solution. To test that hypothesis, the team increased the size of their previous model, GPT-2, from 1.5 billion parameters to 175 billion. For training, the team collected several datasets, including the Common Crawl dataset and the English-language Wikipedia. The model was evaluated against several NLP benchmarks, matching state-of-the-art performance on “closed-book” question-answering tasks and setting a new record for the LAMBADA language modeling task.

OpenAI made headlines last year with GPT-2 and their decision not to release the 1.5 billion parameter version of the trained model due to “concerns about malicious applications of the technology.” GPT-2 is one of many large-scale NLP models based on the Transformer architecture. These models are pre-trained on large text corpora, such as the contents Wikipedia, using self-supervised learning. In this scenario, instead of using a dataset containing inputs paired with expected outputs, the model is given a sequence of text with words “masked” and it must learn to predict the masked words based on the surrounding context. After this pre-training, the models are then fine-tuned with a labelled benchmark dataset for a particular NLP task, such as question-answering.

Jun 2, 2020

How will the pandemic alter research funding?

Posted by in categories: biotech/medical, economics, employment, finance

As the pandemic’s economic toll grows around the world, some experts fear it could harm science for decades by putting many thousands of researchers out of work and forcing nations to slash funding as they rebuild societies. Others say the pandemic could highlight the importance of science and spur long-term support, especially for basic research, much as the Second World War did.


Financial crises could spell trouble for science budgets but spending could surge in some countries: part 2 in a series on science after the pandemic.

Jun 2, 2020

Why this trick should be IMPOSSIBLE ft. Rodney Mullen — Skateboarding Science

Posted by in categories: engineering, physics, science

Skateboarding legend Rodney Mullen teams up with Physics Girl to explain the unusual physics behind skateboard tricks. Filmed with a phantom high speed camera at 1000fps, see Mullen’s tricks like never before.

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