Lifeboat Foundation

The prediction of protein structures from amino acid sequence information alone, known as the “protein folding problem,” has been an important open research question for more than 50 years. In the fall of 2020, DeepMind’s neural network model AlphaFold took a huge leap forward in solving this problem, outperforming some 100 other teams in the Critical Assessment of Structure Prediction (CASP) challenge, regarded as the gold-standard accuracy assessment for protein structure prediction. The success of the novel approach is considered a milestone in protein structure prediction.

This week, the DeepMind paper Highly Accurate Protein Structure Prediction with AlphaFold was published in the prestigious scientific journal Nature. The paper introduces AlphaFold2, a completely redesigned and open-sourced model that can predict protein structures with atomic-level accuracy.

Although machine learning researchers have long sought to develop computational methods for predicting 3D protein structures from protein sequences, there had been limited progress along this path, chiefly due to the computational intractability of molecular simulation, the context-dependence of protein stability, and the difficulty of producing sufficiently accurate models for protein physics.

BlueOcean, a startup leveraging AI and machine learning to measure brand sentiment, has raised $15 million in capital.

The super app, synonymous with popular mobile apps like WeChat, Grab, GoTo and Paytm, has enjoyed noteworthy success in Asian countries, but is relatively absent in other markets. CNBC’s Nessa Anwar, joined by Arjun Kharpal, explains the strategies and evolution behind the world’s biggest super apps.

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Continue reading “What is a super app, and why haven’t they gone global? | CNBC Explains” »

MIT physicists have observed signs of a rare type of superconductivity in a material called magic-angle twisted trilayer graphene. In a study appearing in Nature, the researchers report that the material exhibits superconductivity at surprisingly high magnetic fields of up to 10 Tesla, which is three times higher than what the material is predicted to endure if it were a conventional superconductor.

The results strongly imply that magic-angle trilayer graphene, which was initially discovered by the same group, is a very rare type of superconductor, known as a “spin-triplet,” that is impervious to high magnetic fields. Such exotic superconductors could vastly improve technologies such as magnetic resonance imaging, which uses superconducting wires under a magnetic field to resonate with and image biological tissue. MRI machines are currently limited to magnet fields of 1 to 3 Tesla. If they could be built with spin-triplet superconductors, MRI could operate under higher magnetic fields to produce sharper, deeper images of the human body.

The new evidence of spin-triplet superconductivity in trilayer graphene could also help scientists design stronger superconductors for practical quantum computing.

No instances of the rare disease had been recorded in the US since 2003.

Amnesty International — part of the group that helped break the news of journalists and heads of state being targeted by NSO’s government-grade spyware, Pegasus — has released a tool to check if your phone has been affected. Alongside the tool is a great set of instructions, which should help you through the somewhat technical checking process. Using the tool involves backing up your phone to a separate computer and running a check on that backup. Read on if you’ve been side-eyeing your phone since the news broke and are looking for guidance on using Amnesty’s tool.

The process is straightforward, but it requires some patience.

As long as a white dwarf star is alive, life will likely not survive.

New research sheds light on the possibility of life emerging on planets orbiting white dwarf stars.

We probably at this point should make all animals immortal: 3.

The advance promises to unlock new insights into human biology and disease, aiding in the study of everything from the developing immune system to tissue regeneration to skin cancer.

“Studying biodiversity is not just about exploring the biology of a bunch of interesting organisms, but ultimately for a better understanding of human biology,” developmental biologist and lead study author Hiroshi Kiyonari said via email.

Continue reading “Scientists produce first genetically engineered marsupials” »

Part of a portable nuclear power plant arrives at Camp Century in 1960. Bettmann Archive/Getty ImagesIn a tunnel 40 feet beneath the surface of the Greenland ice sheet, a Geiger counter screamed. It was 1964, the height of the Cold War. U.S. soldiers in the tunnel, 800 miles from the North Pole, were dismantling the Army’s first portable nuclear reactor. Commanding Officer Joseph Franklin grabbed the radiation detector, ordered his men out and did a quick survey before retreating from the reactor.