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May 2, 2020

Smart chips for space

Posted by in categories: computing, space

Tiny integrated circuits destined for space missions, etched onto a single wafer of silicon, examined under a magnifier.

To save money on the high cost of fabrication, various chips designed by different companies and destined for multiple ESA projects are crammed onto the same silicon wafers, etched into place at specialised semiconductor manufacturing plants or ‘fabs’.

Once manufactured, the chips, still on the wafer, are tested. The wafers are then chopped up. They become ready for use when placed inside protective packages – just like standard terrestrial microprocessors – and undergo final quality tests.

May 2, 2020

Bat coronavirus phylogeography in the Western Indian Ocean

Posted by in category: biotech/medical

Scientific Reports volume 10, Article number: 6873 (2020) Cite this article.

May 2, 2020

U.S. Health Insurers Benefit as Elective Care Cuts Offset Coronavirus Costs

Posted by in categories: biotech/medical, health

NEW YORK — As Americans delay elective surgeries and avoid doctors and hospitals during the coronavirus pandemic, healthcare spending declines have more than offset the added costs of COVID-19 care, insurance executives and experts say, boosting U.S. health insurer profits.

May 2, 2020

Nanostimulators boost stem cells for muscle repair

Posted by in categories: biotech/medical, life extension

In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells.

May 2, 2020

On average, Wisconsin is pumping nation’s cheapest gas

Posted by in category: economics

MANITOWOC COUNTY (WLUK) — Fewer drivers on the road, means fewer and fewer people are filling up their tank. “With consumers are staying at home and the economy in troubled waters, I think that’s kind of the best summary. People are just not driving,” said GasBuddy Head Petroleum Analyst Patrick De Haan. At one point Friday morning, the Francis Creek Shell station was selling the cheapest gas in the country at just 75 cents a gallon.

May 2, 2020

WE NEED MORE REJUVENATION TRANSLATORS! NTZ Co-founders Nicolas Chernavsky & Nina Torres Zanvettor

Posted by in category: life extension

I hope you can take the time to watch my interview with Nicolas Chernavsky & Nina Torres Zanvettor where we discuss their rejuvenation translation company NTZ Publicações and why we need more rejuvenation translators to join their team to spread rejuvenation science globally to a mainstream audience. Discord Brent Nally#0616 TikTok @brentnally Telegram @BrentNally Snapchat brentnally Mixer BrentNally

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May 2, 2020

The Second Study on Vitamin D and COVID-19 Is Now Out

Posted by in categories: biotech/medical, government, health, sex

The first study on vitamin D and COVID-19 was released as a preprint on April 23, and a second study was released as a preprint on April 26. Here’s what we can learn from the second study. The first study, which I reported on a few days ago, focused on disease severity, while the second one, which I’m reporting on here, focused on mortality.

The Results

The electronic health records of 780 laboratory-confirmed COVID-19 cases from the government hospitals of Indonesia between March 2 and April 24 was searched for data on vitamin D status prior to admission, age, sex, preexisting conditions, and mortality. Vitamin D status was classified as normal (≥30 ng/mL), insufficient (21−29 ng/mL), or deficient (≤20 ng/mL).

May 2, 2020

Hope Biosciences gets FDA nod for phase 2 COVID-19 stem cell therapy trial

Posted by in category: biotech/medical

Hope Biosciences has been given clearance from the US Food and Drug Administration (FDA) to move ahead with a phase 2 trial to evaluate its investigational stem cell therapy in providing immune support against COVID-19.

May 2, 2020

US invests hundreds of millions to produce Covid-19 vaccines

Posted by in categories: biotech/medical, genetics

Jordan says Moderna is able to scale up quicker than traditional manufacturers, as its vaccines are created by manipulating mRNA, the molecule that carries genetic instructions from DNA to a cell’s protein-making ribosome. Moderna manipulates mRNA so that it instructs human cells to produce certain viral proteins; the proteins themselves don’t cause infection, but they do invoke an immune response. “The RNA uses the human body as its bioreactor,” says Jordan, so Moderna itself doesn’t have to manufacture the proteins. “To create a different vaccine candidate [for Moderna] is to trigger a different RNA sequence. We don’t need to build a different cell processing plant,” says Jordan.

The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred back from protein to either protein or nucleic acid.— Francis Crick.

The dogma is a framework for understanding the transfer of sequence information between information-carrying biopolymers, in the most common or general case, in living organisms. There are 3 major classes of such biopolymers: DNA and RNA (both nucleic acids), and protein. There are 3×3=9 conceivable direct transfers of information that can occur between these. The dogma classes these into 3 groups of 3: three general transfers (believed to occur normally in most cells), three special transfers (known to occur, but only under specific conditions in case of some viruses or in a laboratory), and three unknown transfers (believed never to occur). The general transfers describe the normal flow of biological information: DNA can be copied to DNA (DNA replication), DNA information can be copied into mRNA (transcription), and proteins can be synthesized using the information in mRNA as a template (translation). The special transfers describe: RNA being copied from RNA (RNA replication), DNA being synthesised using an RNA template (reverse transcription), and proteins being synthesised directly from a DNA template without the use of mRNA. The unknown transfers describe: a protein being copied from a protein, synthesis of RNA using the primary structure of a protein as a template, and DNA synthesis using the primary structure of a protein as a template — these are not thought to naturally occur. [6].

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May 2, 2020

From DNA to protein — 3D

Posted by in categories: biotech/medical, genetics, neuroscience

We can reprogram our DNA. The nucleus of a cell is not read only. It is actually read and write. Basically, the cell is a programmable device, in response to environmental information.

The templates for protein synthesis are RNA (ribonucleic acid) molecules. In particular, a class of RNA molecules called messenger RNA (mRNA) are the information-carrying intermediates in protein synthesis. Other RNA molecules, such as transfer RNA (tRNA) and ribosomal RNA (rRNA), are part of the protein-synthesizing machinery. All forms of cellular RNA are synthesized by RNA polymerases that take instructions from DNA templates. This process of transcription is followed by translation, the synthesis of proteins according to instructions given by mRNA templates.

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