Lifeboat Foundation

Revolutionizing Musculoskeletal Health Through Microcapsule Drug Delivery — Dr. @George R. Dodge, Ph.D. — CEO & Co-Founder — Mechano-Therapeutics LLC

Dr. George R. Dodge, Ph.D. is CEO & Co-Founder of Mechano-Therapeutics LLC (https://mechano-therapeutics.com/), a biotechnology company spun out from his lab, and the labs of his partners Dr. Rob Mauck and Dr. Daeyeon Lee, at the University of Pennsylvania, specializing in microcapsule development using proprietary microfluidics for drug encapsulation, with a mission to revolutionize musculoskeletal health using an innovative platform technology to enhance delivery of therapeutics for improving patient outcomes.

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We live in a tech-enabled world, but for organizations to advance world-changing innovations, they need skilled people who can build, install, and maintain the systems that underlie them. Finding that talent is one of the biggest ongoing problems — and opportunities — in tech.

The P2PInfect botnet worm is going through a period of highly elevated activity volumes starting in late August and then picking up again in September 2023.

P2PInfect was first documented by Unit 42 in July 2023 as a peer-to-peer malware that breaches Redis instances using a remote code execution flaw on internet-exposed Windows and Linux systems.

Cado Security researchers who have been following the botnet since late July 2023, report today seeing global activity, with most breaches impacting systems in China, the United States, Germany, Singapore, Hong Kong, the UK, and Japan.

It lets researchers extract pixel-by-pixel information from nanoscale.

The nanoscale refers to a length scale that is extremely small, typically on the order of nanometers (nm), which is one billionth of a meter. At this scale, materials and systems exhibit unique properties and behaviors that are different from those observed at larger length scales. The prefix “nano-” is derived from the Greek word “nanos,” which means “dwarf” or “very small.” Nanoscale phenomena are relevant to many fields, including materials science, chemistry, biology, and physics.

Living things act with purpose. But where does purpose come from? How do humans make sense of their relation to the world and realize their ability to effect change? These fundamental questions of agency – acting with purpose – have perplexed some of the greatest minds in history including Sir Isaac Newton, Charles Darwin, Erwin Schrödinger, and Niels Bohr.

New research from Florida Atlantic University reveals groundbreaking insight into the origins of agency using an unusual and largely untapped source – human babies. Since goal-directed action appears in the first months of human life, the FAU research team used young infants as a test field to understand how spontaneous movement transforms into purposeful action.

For the study, infants began the experiment as disconnected observers. However, when researchers tethered one of the infants’ feet to a crib-mounted baby mobile, infants discovered they could make the mobile move. To catch this moment of realization like lightning in a bottle, researchers measured infant and mobile movement in 3D space using cutting-edge motion capture technology to uncover dynamic and coordinative features marking the “birth of agency.”

For the first time, a team from the University of Minnesota Twin Cities has synthesized a thin film of a unique topological semimetal material that has the potential to generate more computing power and memory storage while using significantly less energy. Additionally, the team’s close examination of the material yielded crucial insights into the physics behind its unique properties.

The study was recently published in the journal Nature Communications.

<em>Nature Communications</em> is a peer-reviewed, open-access, multidisciplinary, scientific journal published by Nature Portfolio. It covers the natural sciences, including physics, biology, chemistry, medicine, and earth sciences. It began publishing in 2010 and has editorial offices in London, Berlin, New York City, and Shanghai.

The universe naturally gravitates towards disorder, and only through the input of energy can we combat this inevitable chaos. This idea is encapsulated in the concept of entropy, evident in everyday phenomena like ice melting, fires burning, and water boiling. However, zentropy theory introduces an additional layer to this understanding.

This theory was developed by a team led by Zi-Kui Liu, the distinguished Dorothy Pate Enright Professor of Materials Science and Engineering at Penn State. The “Z” in zentropy is derived from the German term “Zustandssumm,” which translates to the “sum over states” of entropy.

Alternatively, Liu said, zentropy may be considered as a play on the term “zen” from Buddhism and entropy to gain insight on the nature of a system. The idea, Liu said, is to consider how entropy can occur over multiple scales within a system to help predict potential outcomes of the system when influenced by its surroundings.

Lithium-ion batteries (LIBs), which store energy leveraging the reversible reduction of lithium ions, power most devices and electronics on the market today. Due to their wide range of operating temperatures, long lifespan, small size, fast charging times and compatibility with existing manufacturing processes, these rechargeable batteries can greatly contribute to the electronics industry, while also supporting ongoing efforts towards carbon neutrality.

The affordable and eco-friendly recycling of used LIBs is a long sought-after goal in the energy sector, as it would improve the sustainability of these batteries. Existing methods, however, are often ineffective, expensive or harmful to the environment.

Moreover, LIBs heavily rely on materials that are becoming less abundant on Earth, such as cobalt and lithium. Approaches that enable the reliable and cost-effective extraction of these materials from spent batteries would drastically reduce the need to source these materials elsewhere, thus helping to meet the growing LIB demand.

Researchers at São Paulo State University (UNESP) in Brazil have developed a strategy for removing glyphosate, one of the world’s most frequently used herbicides, from water. Inspired by the concept of the circular economy, the technique is based on sugarcane bagasse, a waste material produced by sugar and ethanol plants.

“Isolated and chemically functionalized sugarcane bagasse fibers can be used as adsorbent material. Glyphosate adheres to its surface and is removed as a water contaminant by filtration, decantation or centrifugation,” Maria Vitória Guimarães Leal, told Agência FAPESP.

She is the first author of an article on the research published in the journal Pure and Applied Chemistry. Adsorption is a process whereby molecules dispersed in a liquid or gaseous medium adhere to a solid insoluble surface, which is typically porous.