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Is Chief Executive Officer and Managing Director of Cynata Therapeutics (https://cynata.com/), a stem cell and regenerative medicine company that is known for its proprietary Cymerus platform, for the scalable and consistent production of mesenchymal stem cell (MSC)-based therapies.

Unlike traditional MSC therapies that rely on multiple donors, the Cymerus manufacturing process ensures that cells for therapeutic use can be produced in virtually limitless quantities from a single donor – making the opportunities endless and attractive from a manufacturing standpoint. The company has completed Phase I studies for Graft vs Host disease & Diabetic Foot Ulcers and have a number of Phase II, and even have a Phase III clinical trial, in progress.

Dr. Kelly has over 20 years’ experience in biopharmaceutical research and development, including almost 15 years focused on the development of mesenchymal stem cell (MSC) based therapies. He joined Cynata in March 2014, initially as Vice President, Product Development, then Chief Operating Officer from May 2019, and since July 2023 has been CEO & MD. At Cynata, he has overseen all stages of the development of the Cymerus induced pluripotent stem cell (iPSC)-derived MSC technology, including the first completed clinical trial of any iPSC-derived product worldwide.

Dr. Kelly previously held positions at Biota Pharmaceuticals, Mesoblast Limited, Kendle International, Amgen and AstraZeneca.

Dr. Kelly holds a Masters in Pharmacy degree from the Robert Gordon University, Aberdeen, a Ph.D. in Pharmaceutical Sciences from Strathclyde University, Glasgow, and he is a Graduate of the Australian Institute of Company Directors (AICD), Melbourne. He is a member of the International Society for Cell and Gene Therapy (ISCT), the International Society for Stem Cell Research (ISSCR), the Royal Pharmaceutical Society and the AICD.

Dr. Kelly also serves on the ISCT Asia-Pacific Industry Committee, the ISSCR Best Practices Working Group for the Development of PSC-Derived Therapies and the Industry Interface Committee of the Center for Commercialization of Regenerative Medicine (CCRM) Australia.

Continue reading “Dr. Kilian Kelly, Ph.D. — CEO, Cynata Therapeutics — iPSC-Derived, Mesenchymal Stem Cell Therapies” | >

Plastics are everywhere—from packaging and textiles to electronics and medical devices. As plastic waste breaks down, it releases microscopic particles that can penetrate our ecosystems, hinder plant growth, and potentially transfer harmful pollutants to organisms, including humans. Therefore, these plastic particles are a potential threat to the ecosystem, especially in their nanoparticulate form (1–100 nm diameter), which can penetrate the environment through different routes, including the soil beneath our feet.

With this in mind, a team of researchers from Japan set out to study the migration behavior of nanoplastics in different soil types. The study was led by Kyouhei Tsuchida, a Ph.D. student from the National Institute of Advanced Industrial Science and Technology (AIST) and Waseda University, Japan, with fellow students Yukari Imoto, Takeshi Saito, and Junko Hara also from AIST, and Professor Yoshishige Kawabe from the Department of Resources and Environmental Engineering, Waseda University. This study was published online in the journal Science of the Total Environment on April 4, 2025.

The researchers focused on the adsorption of the nanoplastics on soil and the aggregation characteristics of both the nanoplastics and soil particles under varying pH conditions. “The aggregation properties of nanoplastics and their adsorption onto soil particle surfaces are known to affect their migration in soil,” notes Tsuchida. “We conducted experiments to analyze these traits to get a better understanding of the migration of nanoplastics.”

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A stem cell treatment helped improve the motor function of two out of four patients with a spinal cord injury in the first clinical study of its kind, Japanese scientists said.

There is currently no effective for paralysis caused by serious spinal cord injuries, which affect more than 150,000 patients in Japan alone, with 5,000 new cases each year.

Researchers at Tokyo’s Keio University are conducting their study using (iPS)—created by stimulating mature, already specialized, cells back into a juvenile state.

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A Japanese university said Friday it has successfully transplanted stem cells into a patient with a spinal cord injury, in the first clinical trial of its kind.

There is currently no effective treatment for paralysis caused by serious , believed to affect more than 100,000 people in Japan alone.

Surgeons at Tokyo’s Keio University want to study whether induced pluripotent stem (iPS) cells can be used to treat the injuries.

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While it may be an unfamiliar sensation to humans, electroreception is relatively commonplace in the animal kingdom. Sharks, bees and even the platypus all share this ability to detect electric fields in their environment.

Scientists at UC Santa Barbara have just added to that list. A team of researchers led by Matthieu Louis found that fruit fly larvae can sense electric fields and navigate toward the negative electric potential using a small set of sensory neurons in their head.

The findings, published in Current Biology, present an immense opportunity. Fruit flies are arguably the most commonly used experimental animals, the basis for studies in fields as disparate as genetics, neurobiology and aging. Uncovering electroreception in fruit flies opens new avenues of research into the basis of this sense and could even lead to new techniques in bioengineering.

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At Stanford HAI, we believe AI is poised to be the most transformative technology of the 21st century. But its benefits won’t be evenly distributed unless we guide its development thoughtfully. The AI Index offers one of the most comprehensive, data-driven views of artificial intelligence. Recognized as a trusted resource by global media, governments, and leading companies, the AI Index equips policymakers, business leaders, and the public with rigorous, objective insights into AI’s technical progress, economic influence, and societal impact.

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Lithium was introduced into psychiatric practice in the late nineteenth century and has since become a standard treatment for severe psychiatric disorders, particularly those characterized by psychotic agitation. It remains the most effective agent for managing acute mania and preventing relapses in bipolar disorder. Despite potential adverse effects, lithium’s use should be carefully considered relative to other treatment options, as these alternatives may present distinct safety and tolerability profiles. The World Health Organization classifies lithium salts as ‘essential’ medications for inclusion in global healthcare systems. Over the past two decades, the growing recognition of lithium’s efficacy—extending beyond mood stabilization to include reducing suicide risk and inducing neuroprotection—has led to its incorporation into clinical practice guidelines.

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Microbial life has dominated Earth’s history but left a sparse fossil record, greatly hindering our understanding of evolution in deep time. However, bacterial metabolism has left signatures in the geochemical record, most conspicuously the Great Oxidation Event (GOE). We combine machine learning and phylogenetic reconciliation to infer ancestral bacterial transitions to aerobic lifestyles, linking them to the GOE to calibrate the bacterial time tree. Extant bacterial phyla trace their diversity to the Archaean and Proterozoic, and bacterial families prior to the Phanerozoic. We infer that most bacterial phyla were ancestrally anaerobic and adopted aerobic lifestyles after the GOE. However, in the cyanobacterial ancestor, aerobic metabolism likely predated the GOE, which may have facilitated the evolution of oxygenic photosynthesis.

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University of Oregon chemists are bringing a greener way to make iron metal for steel production closer to reality, a step towards cleaning up an industry that’s one of the biggest contributors to carbon emissions worldwide. The research was published in ACS Energy Letters.

Last year, UO chemist Paul Kempler and his team reported a way to create iron with electrochemistry, using a series of chemical reactions that turn saltwater and into pure iron metal.

In their latest work, they’ve optimized the starting materials for the process, identifying which kinds of iron oxides will make the chemical reactions the most cost-effective. That’s a key to making the process work at an industrial scale.

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Although ADHD was orig­i­nal­ly con­sid­ered to be a dis­or­der of child­hood, it has been clear for years that it also impacts adults. At least 60% of chil­dren diag­nosed with ADHD strug­gle with symp­toms into adult­hood and the esti­mat­ed preva­lence of ADHD in adults is between 4 and 5%. As with chil­dren and teens, med­ica­tion treat­ment is…

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