As 6G development continues, China Mobile has successfully achieved another milestone by downloading a 50GB file in less than two seconds
Get the latest international news and world events from around the world.
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes
University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a “two-in-one” molecule that can simultaneously turn off two notoriously difficult-to-target cancer-related genes, KRAS and MYC, as well as directly deliver drugs to tumors that express these genes. This advance holds special promise for treating cancers that have been historically challenging to treat.
The new technology incorporates novel compositions of inverted RNAi molecules that have shown a marked ability to co-silence mutated KRAS and over-expressed MYC. RNA interference (RNAi) is a cellular process that uses small interfering RNAs (siRNAs) to selectively turn off, or silence, mutated genes. The co-silencing resulted in up to a 40-fold improvement in inhibition of cancer cell viability compared to the use of individual siRNAs.
The laboratory findings were published in the Journal of Clinical Investigation on July 31.
Researchers create shape-shifting robot that liquifies to escape cage
Researchers from China and us create shape shifting robot:
In a scene straight out of science fiction, researchers from China and the U.S. have developed a shape-shifting robot made from magnetically responsive liquid metal that can melt, flow, escape confinement, and reassemble itself—all on command.
Inspired by sea cucumbers and powered by gallium, a metal with a melting point just above room temperature, the robot can switch between solid and liquid states using magnetic fields. During tests, it was able to melt, escape from a prison-like cage, and then re-solidify into its original form—without losing function.
Unlike traditional rigid robots, this breakthrough allows machines to:
* Navigate tight or complex spaces * Heal themselves or split apart to avoid damage * Perform surgical tasks inside the human body without invasive procedures * Transition between tool-like solidity and liquid flexibility.
The magnetic fields not only induce the phase change but also control movement, making the robot swim, climb walls, and even jump. Researchers envision future uses in minimally invasive medicine, like removing foreign objects from internal organs, or in electronic assembly, where the robot could flow into hard-to-reach places and form circuits.
Israeli-made flying cars may be floating into our future
For nearly 60 years, the dream of flying cars that many Baby Boomers grew up on while watching TV’s George Jetson jet around the skyways has remained unfulfilled.
But the dream is still alive. A dozen startups around the world are developing VTOLs (“vertical takeoff and landing”) – the technical term for flying cars.
One of the most intriguing of those companies is right here in Israel. Yavneh-based Urban Aeronautics is developing CityHawk to be an eventual “Uber of the air.”
Quantitative and Compositional MRI of the Articular Cartilage: A Narrative Review
This review examines the latest advancements in compositional and quantitative cartilage MRI techniques, addressing both their potential and challenges. The integration of these advancements promises to improve disease detection, treatment monitoring, and overall patient care. We want to highlight the pivotal task of translating these techniques into widespread clinical use, the transition of cartilage MRI from technical validation to clinical application, emphasizing its critical role in identifying early signs of degenerative and inflammatory joint diseases. Recognizing these changes early may enable informed treatment decisions, thereby facilitating personalized medicine approaches. The evolving landscape of cartilage MRI underscores its increasing importance in clinical practice, offering valuable insights for patient management and therapeutic interventions.
New model explains plutonium’s peculiar behavior
Normally, materials expand when heated. Higher temperatures cause atoms to vibrate, bounce around and take up a larger volume. However, for one specific phase of plutonium—called delta-plutonium—the opposite inexplicably occurs: it shrinks above room temperature.
As part of its national security mission, Lawrence Livermore National Laboratory (LLNL) aims to predict the behavior of plutonium in all of its phases. Unraveling the mystery behind delta-plutonium’s abnormal behavior at high temperatures is an important piece of the picture.
In a new study, published in Reports on Progress in Physics, researchers from LLNL demonstrate a model that can reproduce and explain delta-plutonium’s thermal behavior and unusual properties. The model calculates the material’s free energy, a quantity that reflects the amount of available or useful energy in a system.
Human intestine shows rapid evolutionary changes compared to other mammals
Research from an international team finds that the human gut is a site of rapid change, with recent and important deviations from other mammals, including our closest living relative, the chimpanzee.
Led by Gray Camp, Ph.D., of Roche Innovation Center in Basel, Switzerland; Jason Spence, Ph.D., of the University of Michigan and Craig Lowe, Ph.D., of Duke University, the team used stem cells to create human, chimp and mouse intestinal organoids—tiny models of the intestine that offer an unprecedented glimpse into the development of the small intestine.
The work was published in the journal Science.
Scientists map the genes behind diet and dementia risk
Concordance was high between imputed and sequenced APOE genotypes. Moreover, the researchers replicated known GWAS associations with diet-related biomarkers.
The authors also noted several limitations to provide context for future research. These include that the study population was predominantly of European ancestry, which may limit the generalizability of findings, and that the specific participant criteria (e.g., overweight, family history of dementia) mean the resource is not representative of the general population. They also advise that potential batch effects from specimen type and study site should be accounted for in future analyses.
This genetic resource enables analyses of genetic contributions to variability in cognitive responses to the MIND diet, supporting integrative analysis with other data types to delineate underlying biological mechanisms. The data will be made available to other researchers via The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS).