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A lush green wall and back-lit fibreglass panels are found on the exterior of an electrical substation extension that was designed by TEF Design to achieve net-zero energy consumption.

Owned by the utility company Pacific Gas and Electric, the Larkin Street Substation Expansion is located on a mid-block site in the city’s Tenderloin neighbourhood. It adjoins a concrete structure built in 1962 to supply power to the northeastern part of San Francisco.

For the constrained site, local firm TEF Design conceived a two-storey addition that totals 12,200 square feet (1,133 square metres). The extension rises 50 feet (15 metres) at its highest point.

Are quantum events required for consciousness in a very special sense, far beyond the general sense that quantum events are part of all physical systems? What would it take for quantum events, on such a micro-scale, to be relevant for brain function, which operates at the much higher level of neurons and brain circuits? What would it mean?

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Menas Kafatos is a physicist and the Director of the Center of Excellence and has served as Founding Dean, Schmid College of Science & Technology at Chapman University.

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Closer to Truth, hosted by Robert Lawrence Kuhn and directed by Peter Getzels, presents the world’s greatest thinkers exploring humanity’s deepest questions. Discover fundamental issues of existence. Engage new and diverse ways of thinking. Appreciate intense debates. Share your own opinions. Seek your own answers.

DNA analysis of thousands of tumors from NHS patients has found a ‘treasure trove’ of clues about the causes of cancer, with genetic mutations providing a personal history of the damage and repair processes each patient has been through.

In the biggest study of its kind, a team of scientists led by Professor Serena Nik-Zainal from Cambridge University Hospitals (CUH) and University of Cambridge, analyzed the complete genetic make-up or whole-genome sequences of more than 12,000 NHS cancer patients.

Because of the vast amount of data provided by , the researchers were able to detect patterns in the DNA of cancer—or ‘mutational signatures’—that provide clues about whether a patient has had a past exposure to environmental causes of cancer such as smoking or UV light, or has internal, cellular malfunctions.