Lifeboat Foundation

On a good day, things exit through the anus. But in rodents and pigs in respiratory distress, oxygen can be absorbed by tissues in the rectum, helping the animals recover, a new study suggests. The scientists behind the research propose that flushing oxygen into the rectum could one day help save human lives if conventional ventilation methods are unavailable.

“It looks like a crazy idea,” says Sean Colgan, a gastroenterologist at the University of Colorado, Boulder, who was not involved in the study. “But if you look at the data, it’s actually a very compelling story.”

Most mammals breathe through their mouths and noses and send oxygen to their body via the lungs. A few aquatic animals, including sea cucumbers and catfish, breathe through their intestines, and the intestinal tissues of humans can readily absorb pharmaceuticals. But no one knew whether oxygen could enter the bloodstream via mammalian intestines.

The secret to longevity is already in the animals around us.

Some species live unexpectedly long lives. By studying how they do it, researchers hope to pinpoint factors affecting human longevity.

Continue reading “Genetic tricks of the longest-lived animals” »

Scientists said the findings indicated that the virus likely recently jumped from animals to humans, but stressed that additional studies are necessary.

Scientists have reportedly discovered a new kind of coronavirus that is believed to have originated in dogs – in what may be the eighth unique form of the bug known to cause disease in humans.

Researchers in a study published in the Clinical Infectious Diseases journal said their findings from patients hospitalized with pneumonia in 2017–2018 underscored the public health threat of animal coronaviruses, Reuters reported.

Continue reading “Scientists find new human coronavirus that originated in dogs” »

Most important part comes at 1:49 where Liza talks about gene therapies for people to stop people from aging, reaching homeostasis, or even exceeding it a little bit.

In this video Liz introduces BioViva Science and how the company works with its partners in delivering gene therapies.

Continue reading “Fighting Aging With Gene Therapies | Liz Parrish Interview Series Episode 2” »

A new study argues we should search for microbial life rather than human-like aliens.

Our recent look at the possibility of technosignatures at Alpha Centauri is now supplemented with a new study on the detectability of artificial lights on Proxima Centauri b. The planet is in the habitable zone, roughly similar in mass to the Earth, and of course, it orbits the nearest star, making it a world we can hope to learn a great deal more about as new instruments come online. The James Webb Space Telescope is certainly one of these, but the new work also points to LUVOIR (Large UV/Optical/IR Surveyor), a multi-wavelength space-based observatory with possible launch in 2035.

Authors Elisa Tabor (Stanford University) and Avi Loeb (Harvard) point out that a (presumably) tidally locked planet with a permanent nightside would need artificial lighting to support a technological culture. As we saw in Brian Lacki’s presentation at Breakthrough Discuss (see Alpha Centauri and the Search for Technosignatures), coincident epochs for civilizations developing around neighboring stars are highly unlikely, making this the longest of longshots. On the other hand, a civilization arising elsewhere could be detectable through its artifacts on worlds it has chosen to study.

We learn by asking questions and looking at data. In this case, asking how we would detect artificial light on Proxima b involves factoring in the planet’s radius, which is on the order of 1.3 Earth radii (1.3 R_⊕) as well as that of Proxima Centauri itself, which is 0.14 that of the Sun (0.14 R_⊙). We also know the planet is in an 11 day orbit at 0.05 AU. Other factors influencing its lightcurve would be its albedo and orbital inclination. Tabor and Loeb use recent work on Proxima Centauri c’s inclination (citation below) to ballpark an orbital inclination for the inner world.

Aliens symbolize the best and worst of humanity. When we dream of aliens, we are pondering our future selves.

Astronomers have long predicted that deep beneath Neptune’s thick blue clouds lies a super-hot body of water that, despite its high temperature, never boils because of its incredibly high-pressure atmosphere. Uranus, another planet in the outer solar system of similar size and composition, is also believed to have a similar water-rich interior. Unfortunately, due to their distances from Earth, it is hard to directly probe these two planets to test our assumption. But scientists have found novel ways of testing their theories about these ice giants from Earth.

As described in a newly-published study from Nature Astronomy, scientists recreated the pressure and temperature of the interiors of Neptune and Uranus in a lab. The aim of the experiments was to test hypotheses about the chemistry of the deep water within these planets. But the study could have additional implications for what we know about potentially habitable planets in other solar systems.

“We were seeking to extend our knowledge of the deep interior of ice giants and determine what water-rock interactions at extreme conditions might exist,” said lead author Taehyun Kim, of Yonsei University in South Korea. “Ice giants and some exoplanets have very deep water layers, unlike terrestrial planets. We proposed the possibility of an atomic-scale mixing of two of the planet-building materials (water and rock) in the interiors of ice giants.”

In our ongoing search to continuously improve our health, we occasionally pay lip service to the bacteria that live inside our gut. Normally this concern rarely manifests as anything more than occasionally remembering to buy some of those small bottles of pro-biotic yoghurts while shopping for your…

Recent discoveries have led to the conclusion that the gut plays an important role in cognitive function, with a large amount of research into understanding what is known as the gut-brain axis, which is the collective name given to the biochemical signalling pathways which take place between the gastrointestinal tract and the central nervous system. With an ever-increasing understanding of this pathway, along with an expanded understand of the gut flora (which was found to decline with age), researchers started to ask how the gut flora are involved in the ageing process.

In order to test how exactly ageing gut flora effects the gut-brain axis, researchers at the University of East Anglia conducted a faecal transplant from elderly mice into younger mice. Following this transplant, the young mice were then put through a serious of tests to assess their cognitive abilities. The younger mice showed significant changes in their microbial profiles, as well as significantly impaired capacity for spatial learning, as well as a decreased capacity for memorisation. These mice also showed an altered expression of proteins associated with neurotransmission and neuroplasticity, along with changes in the mice’s hippocampus, which is responsible for allowing the mice to memories new information, as well as recalling previous memories.

Continue reading “Faecal transplantation: the cure for forgetfulness?” »