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Mar 14, 2024

Next-generation stool DNA test found to have best detection rate of noninvasive colorectal cancer screening tools

Posted by in categories: biotech/medical, chemistry

A study of more than 21,000 average risk patients at 186 sites across the U.S., led by Regenstrief Institute and Indiana University School of Medicine research scientist Thomas Imperiale, M.D., has found that the next-generation multi-target stool DNA colorectal cancer screening test detects 94% of colorectal cancers. This test has the best performance for detection of both colorectal cancer and advanced precancerous polyps of any noninvasive colorectal cancer screening test.

The study results are published in the New England Journal of Medicine.

“We found that the next-generation stool DNA test had a good balance of sensitivity—detecting disease—and specificity—low false positive results. Compared to the fecal immunochemical test (FIT), the next gen test had superior sensitivity for both colorectal cancer and advanced pre-cancerous polys, especially the subgroup of advanced polyps containing high grade dysplasia,” said Dr. Imperiale, first author of the study.

Mar 14, 2024

Elon Musk says AI will be smarter than any human next year

Posted by in categories: Elon Musk, Ray Kurzweil, robotics/AI

Musk made this comment while reposting a clip from Joe Rogans podcast with American computer scientist Ray Kurzweil. The topic was when AI will achieve human-level intelligence. Musk said that “AI will probably be smarter than any single human next year.”

Mar 14, 2024

Claude 3 Haiku: our fastest model yet

Posted by in category: robotics/AI

Anthropic releases Claude 3 Haiku Claude 3 Haiku is three times faster than its peers for the vast majority of workloads, processing 21K tokens (~30 pages) per second for prompts under 32K tokens.

Anthropic releases Claude 3 Haiku.

Claude 3 Haiku is three times faster than its peers for the vast majority of workloads, processing 21K tokens (~30 pages) per second for prompts under 32K tokens.

Continue reading “Claude 3 Haiku: our fastest model yet” »

Mar 14, 2024

A blood test for colon cancer performed well in a study, expanding options for screening

Posted by in categories: biotech/medical, health

A blood test for colon cancer performed well in a study published Wednesday, offering a new kind of screening for a leading cause of cancer deaths.

The test looks for DNA fragments shed by tumor cells and precancerous growths. It’s already for sale in the U.S. for $895, but has not been approved by the Food and Drug Administration and most insurers do not cover it. The maker of the test, Guardant Health, anticipates an FDA decision this year.

In the study, the test caught 83% of the cancers but very few of the precancerous growths found by colonoscopy, the gold standard for colon cancer screening. Besides spotting tumors, colonoscopies can prevent the disease by removing precancerous growths called polyps.

Mar 14, 2024

Robotic breakthrough

Posted by in categories: innovation, robotics/AI

Figure: We are now having full conversations with Figure 1, thanks to our partnership with OpenAI.

Our robot can: — describe its visual experience — plan future actions — reflect on its memory — explain its reasoning verbally.

Mar 14, 2024

Ford CEO, who’s been worrying about China’s EV dominance for years, says ‘the world has changed’ and he’d work with rivals on a cheaper battery

Posted by in category: futurism

Jim Farley has a Tesla veteran heading up a Ford “skunkworks” team to develop low-cost EVs, but he’s open to cooperation with rivals on batteries.

Mar 14, 2024

Boots CEO says his 5-day office return will create a ‘fun’ workplace; working moms are unlikely to agree

Posted by in category: futurism

Mar 13, 2024

‘GPS nanoparticle’ platform precisely delivers therapeutic payload to cancer cells

Posted by in categories: biotech/medical, genetics, nanotechnology

A newly developed “GPS nanoparticle” injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique may potentially offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.

Mar 13, 2024

Researchers ‘film’ the activation of an important receptor

Posted by in category: futurism

An international team of researchers has succeeded in “filming” the activation of an important receptor. They froze the involved molecules at different points in time and photographed them under the electron microscope. They were then able to place these still images in sequence. This sequence shows step by step which spatial changes the receptor undergoes when it is activated.

Mar 13, 2024

How to upcycle low-energy light: A new design for highly efficient conversion materials

Posted by in categories: biotech/medical, materials

To combine two low-energy photons into one high-energy photon efficiently, the energy must be able to hop freely, but not too quickly, between randomly oriented molecules of a solid. This Kobe University discovery provides a much-needed design guideline for developing materials for more efficient PV cells, displays, or even anti-cancer therapies.

Light of different colors has different energies and is therefore useful for very different things. For the development of more efficient PV cells, OLED displays, or anti-cancer therapies, it is desirable to be able to upcycle two low-energy photons into a high-energy , and many researchers worldwide are working on materials for this up-conversion.

During this process, light is absorbed by the material, and its energy is handed around among the material’s as a so-called “triplet exciton.” However, it was unclear what allows two triplet excitons to efficiently combine their energies into a different excited state of a single molecule that then emits a high-energy photon, and this knowledge gap has been a serious bottleneck in the development of such materials.

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