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In 2017, Jacob Haendel was living a normal life as a head chef in…


A paralysed man who had an extreme form of locked-in syndrome and heard a nurse say he was “brain dead” has become the first ever to recover after hearing medical professionals debating whether or not to switch off his life support.

In 2017, Jacob Haendel was living a normal life as a head chef in Boston, Massachusetts but in the space of a few weeks, his life was turned upside down after he was diagnosed with acute toxic progressive leukoencephalopathy, which progressed into locked-in syndrome and forced his body would slowly shut down. An extreme form of locked-in syndrome is a condition where a patient is aware but cannot move or communicate verbally due to complete paralysis and can be caused by brain trauma, infection or exposure to toxins.

It is not known exactly how Jacob developed the condition, though he says his life as a chef consuming certain chemicals “wilfully and otherwise” may have been a factor. He ended up paralysed, unable to talk or blink within a few months and, could hear hospital staff deliberating over switching off machines.

The type of semiconductive nanocrystals known as quantum dots are both expanding the forefront of pure science and also hard at work in practical applications including lasers, quantum QLED televisions and displays, solar cells, medical devices, and other electronics.

A sensitive perception of the environment is crucial for guiding our behavior. However, an overly sensitive response of the brain’s neural circuits to stimuli can lead to neurodevelopmental disorders such as epilepsy. University of Basel researchers report in the journal Nature how neuronal networks in the mouse brain are fine-tuned.

One of the characteristics of depression is a tendency to perceive sensory stimuli and everyday situations in an excessively negative way. But the mechanisms underpinning this “negativity bias,” which can fuel the development of depressive symptoms, had previously remained largely unknown.

As technology advances, the limitations of conventional electronic computers are becoming increasingly apparent, especially when tackling complex computational challenges. NP-complete problems, which grow exponentially with size, represent some of the toughest puzzles in computer science. These issues have significant implications across various fields, including biomedicine, transportation, and manufacturing. In the quest for more effective…

A new study sheds light on how highly creative individuals, such as visual artists and scientists, may have brains that function differently compared to others. The research, published in Psychology of Aesthetics, Creativity, and the Arts, reveals that people who exhibit exceptional creativity—referred to as “Big C” creative individuals—demonstrate…

Different brain regions are connected by—and interact through—networks of neurons. But the extent to which neuronal wiring drives shared function between these different regions is not well understood. Is this structure-function relationship the same throughout the brain? The same across functions?

The study of X-ray emission from astronomical objects reveals secrets about the universe at the largest and smallest spatial scales. Celestial X-rays are produced by black holes consuming nearby stars, emitted by the million-degree gas that traces the structure between galaxies, and can be used to predict whether stars may be able to host planets hospitable to life.