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Summary: Researchers have released a whole-brain projectome consisting of over 6,000 single neurons in the mouse prefrontal cortex.

Source: Chinese Academy of Science.

In a study published in Nature Neuroscience, scientists at the Center for Excellence in Brain Science and Intelligence Technology (CEBSIT) of the Chinese Academy of Sciences, along with their collaborators, reported the first release of a whole-brain projectome comprising over 6,000 single neurons in the mouse prefrontal cortex (PFC), making it the largest database of a whole-brain, single-neuron mouse projectome to date.

The dissemination of synthetic biology into materials science is creating an evolving class of functional, engineered living materials that can grow, sense and adapt similar to biological organisms.

Nature has long served as inspiration for the design of materials with improved properties and advanced functionalities. Nonetheless, thus far, no synthetic material has been able to fully recapitulate the complexity of living materials. Living organisms are unique due to their multifunctionality and ability to grow, self-repair, sense and adapt to the environment in an autonomous and sustainable manner. The field of engineered living materials capitalizes on these features to create biological materials with programmable functionalities using engineering tools borrowed from synthetic biology. In this focus issue we feature a Perspective and an Article to highlight how synergies between synthetic biology and biomaterial sciences are providing next-generation engineered living materials with tailored functionalities.

SpaceX’s first upgraded 33-engine Super Heavy booster appears to have passed a crucial test with surprising ease, boding well for a smooth qualification process.

Attempting that test so early on did not appear to be SpaceX’s initial plan. Instead, shortly before Super Heavy Booster 4’s third and likely final removal from Starbase’s ‘orbital launch mount’ (OLM) on March 24th, SpaceX transported a massive structural test stand from a Starbase storage yard to the orbital launch site (OLS), where technicians have focused on modifying nearby ground systems to support apparent structural testing of Super Heavy Booster 7. As of March 31st, all available evidence suggested that SpaceX was preparing that stand to verify Booster 7’s mechanical strength and simulate the major stresses it might experience before investing a significant amount of time and resources in qualification testing.

However, SpaceX appeared to change its plans at the last minute.

Oxford spinoff First Light Fusion says its novel “projectile” approach offers “the fastest, simplest and cheapest route to commercial fusion power.” The company is now celebrating a significant breakthrough with its first confirmed fusion reaction.

The nuclear fusion space is heating up, if you’ll pardon the pun, as the world orients itself toward a clean energy future. Where current nuclear power plants release energy by splitting atoms in fission reactions, fusion reactors will release energy in the same way the Sun does – by smashing atoms together so hard and so fast that they fuse into higher elements.

Most of the big tokamak and stellarator-based fusion projects in progress now intend to create monstrously high temperatures, higher than in the core of the Sun, in magnetically confined plasma, hoping to get those atoms moving fast enough to overcome the powerful repulsion between two nuclei.

Using a “laser pincer,” scientists can generate their own antimatter, simulations show.


An international team of physicists have come up with a way to generate antimatter in the lab, allowing them to recreate conditions that are similar to those near a neutron star.

This setup, at Helmholtz-Zentrum Dresden-Rossendorf (HZDR) research laboratory in Germany, involves two high-intensity laser beams that can generate a jet of antimatter, as outlined in a paper published earlier this summer in the journal Communications Physics. That could make antimatter-based research far more accessible for scientists around the world.

It is well established that quantum error correction can improve the performance of quantum sensors. But new theory work cautions that unexpectedly, the approach can also give rise to inaccurate and misleading results—and shows how to rectify these shortcomings.

Quantum systems can interact with one another and with their surroundings in ways that are fundamentally different from those of their classical counterparts. In a quantum sensor, the particularities of these interactions are exploited to obtain characteristic information about the environment of the quantum system—for instance, the strength of a magnetic and electric field in which it is immersed. Crucially, when such a device suitably harnesses the laws of quantum mechanics, then its sensitivity can surpass what is possible, even in principle, with conventional, classical technologies.

Unfortunately, quantum sensors are exquisitely sensitive not only to the physical quantities of interest, but also to noise. One way to suppress these unwanted contributions is to apply schemes collectively known as quantum error correction (QEC). This approach is attracting considerable and increasing attention, as it might enable practical high-precision quantum sensors in a wider range of applications than is possible today. But the benefits of error-corrected quantum sensing come with major potential side effects, as a team led by Florentin Reiter, an Ambizione fellow of the Swiss National Science Foundation working in the group of Jonathan Home at the Institute for Quantum Electronics, has now found. Writing in Physical Review Letters, they report theoretical work in which they show that in realistic settings QEC can distort the output of quantum sensors and might even lead to unphysical results.