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Summary: New findings reveal how anesthesia-induced unconsciousness differs from normal sleep in relation to delta wave activity in the brain.

Source: picower institute for learning and memory.

Imagine the conscious brain as a sea roiling with the collisions and dispersals of waves of different sizes and shapes, swirling around and flowing across in many different directions. Now imagine that an ocean liner lumbers through, flattening everything that trails behind with its powerful, parting wake.

Have you ever made a mistake that you wish you could undo? Correcting past mistakes is one of the reasons we find the concept of time travel so fascinating. As often portrayed in science fiction, with a time machine, nothing is permanent anymore – you can always go back and change it. But is time travel really possible in our universe, or is it just science fiction?

Our modern understanding of time and causality comes from general relativity. Theoretical physicist Albert Einstein’s theory combines space and time into a single entity – “spacetime” – and provides a remarkably intricate explanation of how they both work, at a level unmatched by any other established theory.

This theory has existed for more than 100 years, and has been experimentally verified to extremely high precision, so physicists are fairly certain it provides an accurate description of the causal structure of our Universe.

By exchanging a classical material for one with unique quantum properties, scientists have made a superconducting circuit that’s capable of feats long thought to be impossible.

The discovery, made by researchers from Germany, the Netherlands, and the US, overturns a century of thought on the nature of superconducting circuits, and how their currents can be tamed and put to practical use.

Low-waste, high-speed circuits based on the physics of superconductivity present a golden opportunity to take supercomputing technology to a whole new level.

A research team from Osaka University in Japan has concluded that a clinical trial of transplanted IPS cell-derived corneal tissue was safe and effective – further evidence that cellular reprogramming with Yamanaka factors is moving towards scalable therapies.

Longevity. Technology: The clinical trial spanned several years and used corneal tissues derived from induced pluripotent stem cells. The tissue was transplanted into four almost-blind patients, and, according to the research team, none of the patients experienced rejection or tumorigenicity of the transplanted cells and all saw improvements in their symptoms, with three experiencing improved eyesight, with one improving from 0.15 to 0.7. Importantly, all were free of side effects one year later.

IPS cells can be generated from any adult cell, with Yamanaka factors – a group of protein transcription factors from four master genes. These induced stem cells demonstrate the significant quality of pluripotency – they can differentiate into all other cell types of the body. This is incredibly useful both for research and for therapy.