Toggle light / dark theme

Nvidia’s software restriction to limit Ethereum mining over the RTX 3,000 graphics cards is officially dead because it’s now irrelevant.

On Friday, an Nvidia spokesperson confirmed that the company had removed the “Lite Hash Rate” limiter after users began reporting (Opens in a new window) the absence of the mining restriction in the latest Nvidia drivers releases for Windows and Linux.

“We don’t believe it’s necessary in the current environment,” the Nvidia spokesperson told PCMag without elaborating.

In 1906, Alois Alzheimer, a psychiatrist and neuroanatomist, reported “a peculiar severe disease process of the cerebral cortex” to a gathering of psychiatrists in Tübingen, Germany.

The case was a 50-year-old woman who suffered from memory loss, delusions, hallucinations, aggression, and confusion – all of which worsened until her untimely death five years later.

In the autopsy, Alzheimer noticed distinctive plaques on her brain. These plaques – clumps of amyloid-beta protein – are still considered to be the cause of Alzheimer’s disease.

Join us on Patreon!
https://www.patreon.com/MichaelLustgartenPhD

Bristle Discount Link (Oral microbiome quantification):
ConquerAging15
https://www.bmq30trk.com/4FL3LK/GTSC3/

TruDiagnostic Discount Link (Epigenetic Testing)
CONQUERAGING!
https://bit.ly/3Rken0n.

Quantify Discount Link (At-Home Blood Testing)
https://getquantify.io/mlustgarten.

Cronometer Discount Link (Daily diet tracking):
https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

Support the channel with Buy Me A Coffee!

Scientists have successfully increased the lifespan of animals and there are first studies which describe how we might reverse aging. So how could we one day rever aging?

🔬 Subscribe for more awesome biomedical research: https://bit.ly/2SRMqhC

📸 IG: instagram.com/clemens.steinek.
🔬Twitter: https://twitter.com/CSteinek.

In the 70s, scientists observed that cells only grow for a limited amount of days in the laboratory (Hayflick limit). Over the years, so-called hallmarks of aging have been uncovered. These hallmarks of aging govern how our cells age and we could try to slow dem down to “reverse aging”.
The first hallmark of aging is mutation. We can acquire mutations by being exposed to UV radiation or certain chemicals or through cell division. Cell divsion also leads to a second hallmark of aging (telomere attrition). Furthermore, our mitochondria start to work less as quality checks do not work properly anymore.
The hallmarks of aging are tightly linked to epigenetics. Epigenetics means that we have mechanisms (DNA methylation, histone modifications) which regulate the activity of genes. Epigenetics governs the development of embryonic stem cells into cells of our body but also impact aging. The loss of mitochondria for example is linked to dysfunctional epigenetic layers. As we age, at least three epigenetic modifications namely H4K16 acetylation, H3K4 trimethylation, or H4K20 trimethylation acumulate. The thing is that epigenetics is reversible… so can we also reverse aging?
Diets have been shown to slow down (and reverse aging to a small degree). Cells also show less damages in their DNA and we find higher levels of proteins which are found in “young cells. The activity of mitochondria is also increased if we undergo caloric restriction. Diets also impact the production of sirtuins which increase the lifespan and reverse aging. Different compounts (such as NMN and remodelin) have been shown to improve the epigenetic landscape which might have an effect on reversing aging. Exercise also might help to reverse aging as it helps to increase the activity of mitochondria. Meditation and having less stress also helps to increase the lengths of telomeres which might help to reverse aging. All in all studies suggests that some hallmarks of aging can be reversed so lets see where that goes!

0:00–0:46 Intro.
0:46–3:53 Hallmarks of Aging.
3:53–6:38 Epigenetics Controls Genes.
6:38–8:45 Reversing Aging: what is known.
8:45–11:25 Reversing Aging through Diets & Sports.
11:25–12:13 My Opinion.

References: