Lifeboat Foundation

“Significant effort has been invested over the years to pinpoint the physical cause of the radiation drive-deficit problem,” Chen said. “We are excited about this discovery as it helps resolve a decade-long puzzle in ICF research. Our findings point the way to an improvement in the predictive capabilities of simulations, which is crucial for the success of future fusion experiments.”

In NIF experiments, scientists use a device called a hohlraum—approximately the size of a pencil eraser—to convert laser energy into X-rays, which then compress a fuel capsule to achieve fusion.

For years, there has been a problem where the predicted X-ray energy (drive) was higher than what was measured in experiments. This results in the time of peak neutron production, or “bangtime,” occurring roughly 400 picoseconds too early in simulations. This discrepancy is known as the “drive-deficit” because modelers had to artificially reduce the laser drive in the simulations to match observed bangtime.

Zheng An, Chenfeng Cao, Cheng-Qian Xu, and D. L. Zhou, Quantum 8, 1421 (2024). Identifying phases of matter presents considerable challenges, particularly within the domain of quantum theory, where the complexity of ground states appears to increase exponentially with system size. Quantum many-body systems exhibit an array of complex entanglement structures spanning distinct phases. Although extensive research has explored the relationship between quantum phase transitions and quantum entanglement, establishing a direct, pragmatic connection between them remains a critical challenge. In this work, we present a novel and efficient quantum phase transition classifier, utilizing disentanglement with reinforcement learning-optimized variational quantum circuits. We demonstrate the effectiveness of this method on quantum phase transitions in the transverse field Ising model (TFIM) and the XXZ model. Moreover, we observe the algorithm’s ability to learn the Kramers-Wannier duality pertaining to entanglement structures in the TFIM. Our approach not only identifies phase transitions based on the performance of the disentangling circuits but also exhibits impressive scalability, facilitating its application in larger and more complex quantum systems. This study sheds light on the characterization of quantum phases through the entanglement structures inherent in quantum many-body systems.

An international research collaboration, including a group from Cornell Engineering, has applied a new X-ray-based reconstruction technique to observe, for the first time, topological defects in a nanoscale self-assembly-based cubic network structure of a polymer-metal composite material imaged over a relatively large sample volume.

The field of organoid intelligence is recognized as groundbreaking. In this field, scientists utilize human brain cells to enhance computer functionality. They cultivate tissues in laboratories that mimic real organs, particularly the brain. These brain organoids can perform brain-like functions and are being developed by Dr. Thomas Hartung and his team at the Johns Hopkins Bloomberg School of Public Health.

For nearly two decades, scientists have used organoids to conduct experiments without harming humans or animals. Hartung, who has been cultivating brain organoids from human skin samples since 2012, aims to integrate these organoids into computing. This approach promises more energy-efficient computing than current supercomputers and could revolutionize drug testing, improve our understanding of the human brain, and push the boundaries of computing technology.

The conducted research highlights the potential of biocomputing to surpass the limitations of traditional computing and AI. Despite AI’s advancements, it still falls short of replicating the human brain’s capabilities, such as energy efficiency, learning, and complex decision-making. The human brain’s capacity for information storage and energy efficiency remains unparalleled by modern computers. Hartung’s work with brain organoids, inspired by Nobel Prize-winning stem cell research, aims to replicate cognitive functions in the lab. This research could open new avenues for understanding the human brain by allowing ethical experimentation. The team envisions scaling up the size of brain organoids and developing communication tools for input and output, enabling more complex tasks.

Scientists integrated lab-grown brain organoids with robots, creating hybrid intelligence. It offers new potential for neurological condition treatments.

Human brain organoids represent a remarkable platform for modeling neurological disorders and a promising brain repair approach. However, the effects of physical stimulation on their development and integration remain unclear. Here, we report that low-intensity ultrasound significantly increases neural progenitor cell proliferation and neuronal maturation in cortical organoids. Histological assays and single-cell gene expression analyses reveal that low-intensity ultrasound improves the neural development in cortical organoids. Following organoid grafts transplantation into the injured somatosensory cortices of adult mice, longitudinal electrophysiological recordings and histological assays reveal that ultrasound-treated organoid grafts undergo advanced maturation. They also exhibit enhanced pain-related gamma-band activity and more disseminated projections into the host brain than the untreated groups. Finally, low-intensity ultrasound ameliorates neuropathological deficits in a microcephaly brain organoid model. Hence, low-intensity ultrasound stimulation advances the development and integration of brain organoids, providing a strategy for treating neurodevelopmental disorders and repairing cortical damage.

From the many worlds interpretation to panpsychism, theories of reality often sound absurd. Here’s how you can figure out which ones to take seriously.

By Eric Schwitzgebel

Large-volume high-resolution X-ray nanotomography is used to identify topological defects emerging in a self-assembled triblock terpolymer single-diamond network.

Nick bostroms simulation argument.

Have you ever paused, looked around, and wondered if everything you see, feel, and experience is real? Or could it be that we’re living in a sophisticated simulation, indistinguishable from reality?

This thought isn’t just a plot from a sci-fi movie; it’s a serious philosophical argument proposed by Nick Bostrom, known as the Simulation Argument. If you’ve ever questioned the nature of reality or pondered over the mysteries of existence, this exploration is for you.

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