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Schizophrenia is a disorder that affects how people act, think, and perceive reality. It is often very difficult to treat because it has many different causes and symptoms. In a study published last month in Cell Reports Medicine, researchers from Tokyo Medical and Dental University (TMDU) have identified an autoantibody—a protein that is produced by the immune system to attach to a specific substance from the individual’s own body, rather than to a foreign substance like a virus or bacteria—in some patients with schizophrenia. Notably, they also found that this autoantibody caused schizophrenia-like behaviors and changes in the brain when they injected it into mice.

When considering possible autoantibodies that might cause schizophrenia, the research team had a specific protein in mind. Previous research has suggested that neural cell adhesion molecule (NCAM1), which helps cells in the brain talk to one another via specialized connections known as synapses, may have a role in the development of schizophrenia.

“We decided to look for autoantibodies against NCAM1 in around 200 healthy controls and 200 patients with schizophrenia,” explains lead author of the study Hiroki Shiwaku. “We only found these autoantibodies in 12 patients, suggesting that they may be associated with the disorder in just a small subset of schizophrenia cases.”

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Methylation clocks are taking the longevity community by storm, but why are they so useful?

Do you know how old you really are? I am not doubting your ability to remember your birthday or questioning the honesty of your parents. Do you, on a fundamental level, know how ‘old’ your body truly is? Now surely that is just the same as the number of years you have been around, which would be your chronological age? Well in reality the answer to how ‘old’ your body is comes down to much more than simply how long you have been around for.

Allow me to explain by falling back to the commonly used automobile analogy. Let’s imagine I bought two identical Ford Escorts in 1982, and then proceeded to place one of them inside a time capsule, where it would be kept at a constant temperature in a non-reactive atmosphere. I then proceeded to drive the second car for the next 40 years. Over that 40 years, this car is going to experience wear and tear, and will most likely break down several times which will require mechanical intervention (analogous to medical intervention). Now, after this 40-year period I am going to take the first car out of storage and compare the two cars side by side. Which car is in the better condition? Well, the car that was preserved, obviously. Which car is likely to last the longest from that point onward? Well, the car which has been preserved, obviously.

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Understanding the early universe has been a goal for scientists for decades. And, now with NASA’s James Webb space telescope, and other technology, we’re finally making some decent strides. A new simulation on early galaxy formation could be another key stepping stone, too.

Researchers created the simulation using machine learning. It then completed over 100,000 hours of computations to create the one-of-a-kind simulation. The researchers named the algorithm responsible for the project Hydo-BAM. They published a paper with the simulation’s findings earlier this year.

Creating a simulation of early galaxy formation has allowed researchers to chart the earliest moments of our universe. These important moments began just after the Big Bang set everything into motion. Understanding these key moments of the formation of the early universe could help us better understand how galaxies form in the universe today.

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One day soon, buildings could become more energy-efficient—and environmentally sustainable—with insulating material developed from wood by researchers in Sweden. The newly-developed material offers as good or even better thermal performance than ordinary plastic-based insulation materials, according to researchers reporting recently in ACS Applied Materials & Interfaces.

Yuanyuan Li, an assistant professor at Wallenberg Wood Science Center, KTH Royal Institute of Technology in Stockholm, says that the new insulating material is an aerogel integrated wood which is made without adding additional substances.

Wood cellulose aerogels themselves are nothing new—researchers have been developing advanced types of aerogels and other composites for the last several years in the Wallenberg Wood Science Center at KTH—but Li says the new method represents a breakthrough in controlled creation of insulating nanostructures in the pores of wood.

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“Functional mutations in the growth hormone pathway” meaning it is not active. What’s good for you as a youngster might not be good for you when you’re old.

Dr Nir Barzilai reveals what the longevity genes project found on why Centenarians live longer, not the longevity genes, not healthy lifestyles in this clip.

Dr. Nir Barzilai is the director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health’s (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging. He is the Ingeborg and Ira Leon Rennert Chair of Aging Research, professor in the Departments of Medicine and Genetics, and member of the Diabetes Research Center and of the Divisions of Endocrinology & Diabetes and Geriatrics.

Continue reading “NOT The Longevity Genes!? Surprising Facts WHY Centenarians LIVE LONGER | Dr Nir Barzilai Clips” | >

Circa 2019

Mark Lawrence (link is external), a postdoctoral scholar in materials science and engineering at Stanford, has moved a step closer to this future with a scheme to make a photon diode — a device that allows light to only flow in one direction — which, unlike other light-based diodes, is small enough for consumer electronics.

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After surgery, some cancer patients can safely skip radiation or chemotherapy, according to two studies exploring shorter, gentler cancer care.

Researchers are looking for ways to precisely predict which cancer patients can avoid unneeded treatment to cut down on harmful side effects and unnecessary costs.

One new study used a blood test to determine which colon cancer patients could skip chemotherapy after surgery. Another suggests some low-risk breast cancer patients can omit radiation after lumpectomy.

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Quantum sensing is poised to revolutionize today’s sensors, significantly boosting the performance they can achieve. More precise, faster, and reliable measurements of physical quantities can have a transformative effect on every area of science and technology, including our daily lives. However, most of these schemes are based on special entangled or squeezed states of light or matter that are difficult to detect. It is a significantly challenging task to harness the full power of quantum-limited sensors and deploy them in real-world scenarios.

A team of physicists at the Universities of Bristol, Bath, and Warwick have found a way to operate mass manufacturable photonic sensors at the quantum limit. They have shown that it is possible to perform high-precision measurements of critical physical properties without the need for sophisticated quantum states of light and detection schemes.

Using ring resonators is a key to this breakthrough discovery. The ring resonators are tiny racetrack structures that guide light in a loop and maximize its interaction with the sample under study. Importantly, ring resonators can be mass-produced in the same way chips in computers and cell phones are.

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For those wondering what type of technology exists beyond 5G, scientists are saying a mobile communications frequency could be its level up. The new technology is called “beam-steering” and remains inaccessible to the current technological capacities.

University of Birmingham Scientists Find Faster Speeds than 5G

Scientists from the University of Birmingham, UK, were the ones that revealed the new technology and suggested that it cannot be accessed with the technology’s current capabilities. The “beam-steering” technology, as detailed by the scientists, is capable of speeds up to 10gbps.

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