A pair of researchers has shown that trying to classify groups of numbers called “torsion-free abelian groups” is as hard as it can possibly be.
The same process that eliminates replication errors also eliminates antiviral agents delivered by the treatments commonly used to fight other RNA viruses, such as HIV, HCV and Ebola virus, which partially explains why SARS-CoV-2 has proven so difficult to treat, Yang said.
The coronavirus that causes COVID-19 has demonstrated a stubborn ability to resist most nucleoside antiviral treatments, but a new study led by an Iowa State University scientist could help to overcome the virus’s defenses.
The study, published recently in the peer-reviewed journal Science, details the structure of a critical enzyme present in SARS-CoV-2, the coronavirus that causes COVID-19. This enzyme, known as the proofreading exoribonuclease (or ExoN), removes nucleoside antiviral medications from the virus’s RNA, rendering most nucleoside analogs-based antiviral treatments ineffective. The new study presents the atomic structures of the ExoN enzyme, which could lead to the development of new methods for deactivating the enzyme and opening the door to better treatments for patients suffering from COVID-19.
Continue reading “The enzyme that allows coronavirus to resist antiviral medications” »
The social networking giant and its CEO have vast ambitions to dominate the next big thing in computing, but other tech giants are in a better position to turn the hype into reality.
A group of medications long prescribed to treat tapeworm has inspired a compound that shows two-pronged effectiveness against COVID-19 in laboratory studies, according to a new publication appearing online in the journal ACS Infectious Disease.
The compound, part of a class of molecules called salicylanilides, was designed in the laboratory of Professor Kim Janda, Ph.D., the Ely R. Callaway, Jr. Professor of Chemistry and director of the Worm Institute for Research and Medicine at Scripps Research, in La Jolla, CA. “It has been known for 10 or 15 years that salicylanilides work against certain viruses,” Janda says. “However, they tend to be gut-restricted and can have toxicity issues.” Janda’s compound overcomes both issues, in mouse and cell-based tests, acting as both an antiviral and an anti-inflammatory drug-like compound, with properties that auger well for its use in pill form.
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You’re on PRO Robotics, and in this video we present the July 2,021 news digest. New robots, drones and drones, artificial intelligence and military robots, news from Elon Musk and Boston Dynamics. All the most interesting high-tech news for July in this Issue. Be sure to watch the video to the end and write in the comments, which news you are most interested in?
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This drone is cleaning windows 1,100 feet above the ground, so humans don’t have to.
Three pioneering technologies have forever altered how researchers do their work and promise to revolutionize medicine, from correcting genetic disorders to treating degenerative brain diseases.
Discussions about how and where we produce food are set to continue for a long time to come as businesses, governments and citizens try to find ways to create a sustainable system that meets the needs of everyone.
It’s perhaps no surprise then that some of the topics covered above are starting to generate interest among the investment community.
Speaking to CNBC’s “Squawk Box Europe” in June, Morgan Stanley’s global head of sustainability research, Jessica Alsford, highlighted this shift.
