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Jul 9, 2021

Harnessing AI to Discover New Drugs: Rewriting the Rulebook for Pharmaceutical Research

Posted by in categories: biotech/medical, robotics/AI

Artificial intelligence (AI) is able to recognize the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated. Moreover, AI helps to find molecules that have the same effect as a natural substance but are easier to manufacture. This opens up huge possibilities for drug discovery, which also has potential to rewrite the rulebook for pharmaceutical research.

Nature has a vast store of medicinal substances. “Over 50 percent of all drugs today are inspired by nature,” says Gisbert Schneider, Professor of Computer-Assisted Drug Design at ETH Zurich. Nevertheless, he is convinced that we have tapped only a fraction of the potential of natural products. Together with his team, he has successfully demonstrated how artificial intelligence (AI) methods can be used in a targeted manner to find new pharmaceutical applications for natural products. Furthermore, AI methods are capable of helping to find alternatives to these compounds that have the same effect but are much easier and therefore cheaper to manufacture.

And so the ETH researchers are paving the way for an important medical advance: we currently have only about 4000 basically different medicines in total. In contrast, estimates of the number of human proteins reach up to 400000, each of which could be a target for a drug. There are good reasons for Schneider’s focus on nature in the search for new pharmaceutical agents. “Most natural products are by definition potential active ingredients that have been selected via evolutionary mechanisms,” he says.

Jul 9, 2021

What Will ESA’s EnVision Learn at Venus?

Posted by in category: space travel

What will ESA’s EnVision mission to Venus add to the growing number of spacecraft investigating our sister planet?

Jul 9, 2021

The cause of Jupiter’s glowing “northern lights” is finally revealed

Posted by in category: space

“Jupiter does this really weird thing where it pulses with a regular beat like clockwork.”


Using data from the Juno spacecraft, scientists traced the chain of events that lead to Jupiter’s mysterious auroras.

Jul 9, 2021

Can we explain dark matter

Posted by in category: cosmology

Dark matter could be even weirder than anyone thought, say cosmologists who are suggesting this mysterious substance that accounts for more than 80% of the universe’s mass could interact with itself.

“We live in an ocean of dark matter, yet we know very little about what it could be,” Flip Tanedo, an assistant professor of physics and astronomy at the University of California Riverside, said in a statement.

Jul 9, 2021

World’s deepest pool with underwater city, caves for exploration opens

Posted by in category: engineering

It makes an Olympic swimming pool look like a puddle.

As if Dubai wasn’t filled with enough record-breaking attractions, the United Arab Emirates metropolis is now home to the world’s deepest pool, complete with an underwater city, caves and more.

“An entire world awaits you at Deep Dive Dubai, the world’s deepest pool,” wrote crown prince of Dubai Sheikh Hamdan bin Mohammed bin Rashid Al Maktoum, on Instagram. He was one of the first to visit the engineering marvel on July 7.

Jul 9, 2021

Scientist Invents Toilet That Turns Poop Into Green Energy

Posted by in categories: cryptocurrencies, energy, sustainability, transportation

The toilet could turn roughly a pound of solid human waste, the average amount a human poops in a day, into an impressive 50 liters of methane gas, according to Cho. That means it can generate half a kilowatt hour of electricity, enough to drive an electric car for three quarters of a mile.

And because its 2021 — a day and age in which nothing is safe from the world of cryptocurrencies — Cho came up with a virtual currency called Ggool, or “honey” in Korean. Every use of the toilet scores you 10 Ggool per day, which can be used to buy stuff on the university’s campus.

“I had only ever thought that feces are dirty, but now it is a treasure of great value to me,” a postgraduate student Heo Hui-jin who’s both earned and spent Ggool, told Reuters. “I even talk about feces during mealtimes to think about buying any book I want.”

Jul 9, 2021

Type 2 diabetes: Could targeting the liver help?

Posted by in category: biotech/medical

They found that insulin sensitivity can be restored within days of reducing excess production of the neurotransmitter GABA in the liver and that long-term treatment may lead to decreased appetite and weight loss.


New research suggests that reducing the production of a neurotransmitter in the liver could help normalize blood sugar and treat type 2 diabetes.

Jul 9, 2021

Need to Fit Billions of Transistors on a Chip? Let AI Do It

Posted by in categories: information science, robotics/AI

Google, Nvidia, and others are training algorithms in the dark arts of designing semiconductors—some of which will be used to run artificial intelligence programs.

Jul 9, 2021

Scientists Solve 40-Year Mystery Over Jupiter’s Spectacularly Powerful X-ray Aurora

Posted by in categories: particle physics, space

A research team has solved a decades-old mystery as to how Jupiter produces a spectacular burst of X-rays every few minutes.

A research team co-led by UCL (University College London) has solved a decades-old mystery as to how Jupiter produces a spectacular burst of X-rays every few minutes.

The X-rays are part of Jupiter’s aurora — bursts of visible and invisible light that occur when charged particles interact with the planet’s atmosphere. A similar phenomenon occurs on Earth, creating the northern lights, but Jupiter’s is much more powerful, releasing hundreds of gigawatts of energy, enough to briefly power all of human civilization.*.

Jul 9, 2021

Hubble Captures Two Gargantuan Galaxies in the Perseus Galaxy Cluster

Posted by in category: space

Two things capture your attention in this spectacular Picture of the Week, which was taken using Hubble’s Wide Field Camera 3 (WFC3): the two enormous galaxies that flank the left and right sides of the image. The galaxy on the left is a lenticular galaxy, which rejoices in the name of 2MASX J03193743+4137580. The side-on spiral galaxy on the right is more simply named UGC 2665. Both galaxies lie approximately 350 million light-years from Earth, and they both form part of the enormous Perseus galaxy cluster.

Perseus is an important figure in Greek mythology, renowned for slaying Medusa the Gorgon — who is herself famous for the unhappy reason that she was cursed to have living snakes for hair. Given Perseus’s impressive credentials, it seems appropriate that the eponymous galaxy cluster is one of the biggest objects in the known Universe, consisting of thousands of galaxies, only a few of which are visible in this image.

The wonderful detail in the image is thanks to the WFC3’s powerful resolution and high sensitivity. The WFC3 is sensitive to both visible and infrared light, so those are the wavelengths that are captured in this image. The Perseus supercluster looks very different at other wavelengths. Whilst in this image the spaces between the galaxies appear dark and peaceful, when the X-ray emission is observed the Perseus cluster appears to be burning with bright intense light.