Lifeboat Foundation

Northwestern University synthetic biologists have developed a low-cost, easy-to-use, hand-held device that can let users know—within mere minutes—if their water is safe to drink.

The new device works by using powerful and programmable genetic networks, which mimic electronic circuits, to perform a range of logic functions.

Among the DNA-based circuits, for example, the researchers engineered cell-free molecules into an analog-to-digital converter (ADC), a ubiquitous circuit type found in nearly all electronic devices. In the water-quality device, the ADC circuit processes an analog input (contaminants) and generates a digital output (a visual signal to inform the user).

Today’s rechargeable batteries are a wonder, but far from perfect. Eventually, they all wear out, begetting expensive replacements and recycling.

“But what if batteries were indestructible?” asks William Chueh, an associate professor of materials science and engineering at Stanford University and senior author of a new paper detailing a first-of-its-kind analytical approach to building better batteries that could help speed that day. The study appears in the journal Nature Materials.

Chueh, lead author Haitao “Dean” Deng, Ph.D. ‘21, and collaborators at Lawrence Berkeley National Laboratory, MIT and other research institutions used artificial intelligence to analyze new kinds of atomic-scale microscopic images to understand exactly why batteries wear out. Eventually, they say, the revelations could lead to batteries that last much longer than today’s. Specifically, they looked at a particular type of lithium-ion batteries based on so-called LFP materials, which could lead to mass-market electric vehicles because it does not use chemicals with constrained supply chains.

Brain organization differs between boys and girls with autism, according to a new study from the Stanford University School of Medicine.

The differences, identified by analyzing hundreds of brain scans with artificial intelligence techniques, were unique to autism and not found in typically developing boys and girls. The research helps explain why autism symptoms differ between the sexes and may pave the way for better diagnostics for girls, according to the scientists.

Autism is a developmental disorder with a spectrum of severity. Affected children have social and communication deficits, show restricted interests and display repetitive behaviors. The original description of autism, published in 1943 by Leo Kanner, MD, was biased toward male patients. The disorder is diagnosed in four times as many boys as girls, and most autism research has focused on males.

Neural cell type diversification during development is a complex and highly regulated process. Here, the authors show that the histone H3-lysine 27 demethylase Kdm6b promotes and inhibits the generation of specific motor neuron subtypes during the development of the mouse spinal cord.

For the first time, researchers have created a metasurface lens that uses a piezoelectric thin film to change focal length when a small voltage is applied. Because it is extremely compact and lightweight, the new lens could be useful for portable medical diagnostic instruments, drone-based 3D mapping and other applications where miniaturization can open new possibilities.

“This type of low-power, ultra-compact varifocal lens could be used in a wide range of sensor and imaging technologies where system size, weight and cost are important,” said research project leader Christopher Dirdal from SINTEF Smart Sensors and Microsystems in Norway. “In addition, introducing precision tunability to metasurfaces opens up completely new ways to manipulate light.”

Dirdal and colleagues describe the new technology in the journal Optics Letters. To change focal length, a voltage is applied over lead zirconate titanate (PZT) membranes causing them to deform. This, in turn, shifts the distance between two metasurface lenses.

Stunning.

For its first science image, the NASA IXPE observatory zoomed in on the remains of a star that exploded in the 17th century, revealing the intensity of X-Ray light coming from the blast.

Equipping ROSALIND, a cell-free biosensing platform, with information processing circuits based on toehold-mediated DNA strand displacement enhances sensor performance and enables logic gate computation.

The most valuable science prizes courtesy of Yuri Milner et al; check it out and poss apply?

Knowledge is humanity’s greatest asset. It defines our nature, and it will shape our future. The body of knowledge is assembled over centuries.

SpaceX readies Starship.

Tesla needs a major change.

Continue reading “Tesla hit with disturbing racial discrimination allegations… again” »