Lifeboat Foundation

Imagine a field of wheat that extends to the horizon, being grown for flour that will be made into bread to feed cities’ worth of people. Imagine that all authority for tilling, planting, fertilizing, monitoring and harvesting this field has been delegated to artificial intelligence: algorithms that control drip-irrigation systems, self-driving tractors and combine harvesters, clever enough to respond to the weather and the exact needs of the crop. Then imagine a hacker messes things up.

Imagine a field of wheat that extends to the horizon, being grown for flour that will be made into bread to feed cities’ worth of people. Imagine that all authority for tilling, planting, fertilizing, monitoring and harvesting this field has been delegated to artificial intelligence: algorithms that control drip-irrigation systems, self-driving tractors and combine harvesters, clever enough to respond to the weather and the exact needs of the crop. Then imagine a hacker messes things up.

A new risk analysis, published today in the journal Nature Machine Intelligence, warns that the future use of artificial intelligence in agriculture comes with substantial potential risks for farms, farmers and food security that are poorly understood and under-appreciated.

“The idea of intelligent machines running farms is not science fiction. Large companies are already pioneering the next generation of autonomous ag-bots and decision support systems that will replace humans in the field,” said Dr. Asaf Tzachor in the University of Cambridge’s Center for the Study of Existential Risk (CSER), first author of the paper.

A professor of physics explains how mind-bending quantum experiments are blurring the line between past, present and future. Further, he argues, these experiments, which factor in ‘the relevance of the future to the present’, may demand a radical rethinking of quantum experimentation itself.

Clues to the season of impact lingered in delicate fish fossils.

Around 66 million years ago, springtime in the Northern Hemisphere brought disaster and mass death to Earth in the form of a giant asteroid impact that triggered a global extinction.

A year after it took biologists by surprise, AlphaFold has changed how researchers work and set DeepMind on a new course.

More recently, digital twins have been the focus of a European Union-funded project that seeks to clone a patient’s entire brain. Dubbed Neurotwin, the research project aims to create virtual models that can be used to predict the effects of stimulation for the treatment of neurological disorders—including epilepsy and Alzheimer’s disease. When it comes to epilepsy, non-invasive stimulations (where electrical currents are painlessly delivered to the brain) have proven effective in tackling seizures. Given how drugs don’t help a third of epilepsy patients, the technology is coveted yet needs refinement. This is where virtual clones come in.

“The digital avatar is essentially a mathematical model running on a computer,” Giulio Ruffini, coordinator of the Neurotwin project, told WIRED. Including a network of embedded “neural mass models,” the technology hopes to create a map of the neural connections in the brain—a concept termed as the ‘connectome’. “In the case of epilepsy, some areas of the connectome could become overexcited,” the outlet mentioned. “In the case of, say, stroke, the connectome might be altered.” Once the digital clone has been created by the team, with about half an hour-worth of magnetic resonance imaging (MRI) data and ten minutes of electroencephalography (EEG) readings to capture electrical activities and realistically simulate the brain’s main tissues (including the scalp, skull, cerebrospinal fluid, and grey and white matter), it can then be used to optimise stimulation of the real patient’s brain.

Continue reading “New project creates digital clones of human brains to help treat neurological disorders” »

No he does not respond to the resveratrol challenges. Important here are the chapters concerning Resetting the Ageing Clock and Repeatable Ageing Reversal.

In the final episode of this season, Dr. David Sinclair and Matthew LaPlante focus on current and near-future technologies relevant to health and aging. In addition to discussing the utility of wearable sensors and biological age measurements, they highlight innovative research aimed at reversing biological age. The societal effects of therapies that successfully extend healthspan and/or lifespan are also considered.

Continue reading “Biotracking, Age Reversal & Other Advanced Health Technologies | Lifespan with Dr. David Sinclair #8” »

Cartography could be changing forever as an advanced tool moves from the lab to the real world. A new quantum gravity sensor helps overcome an issue raised by Einstein.

Public policy includes efforts by governmental as well as nongovernmental agencies (other than professional associations) to manage genetic enhancement. For example, the International Olympic Committee has a policy on performance-enhancing drugs in sport. In the United States, the Food and Drug Administration classified synthetic anabolic steroids as a restricted class of drugs, making it more difficult to get access to them. Such measures will not always be successful. Epoetin alfa (EPO) is a useful medication for the many people who suffer from chronic anemia, including people who must undergo regular renal dialysis. As a consequence, it is in very wide supply for legitimate therapeutic purposes, unlike the synthetic anabolic steroids. Imposing strict limitations on access to EPO would create an enormous inconvenience for the large number of people who benefit from the drug. The fact that some athletes are able to get their hands on EPO is an unintended consequence of having the drug widely available for legitimate therapeutic uses. The appropriate public policy will not be the same, necessarily, for every drug.

By “personal policy” we mean the moral understandings and social practices of individuals, parents, and families, including those moral convictions that would cause them to refrain from unwise or unfair use of genetic enhancement technologies. The Worth of a Child, for example, focuses on ethical issues involving children and parents.¹¹ How does one engage that sort of personal policy response? The means we have are limited but powerful: education, public dialogue, and the encouragement of ethical reflection.

In conclusion, there are four points worth reiterating. First, as we think about genetic enhancement, we should use a broad definition of genetic-enhancement technologies, not merely gene manipulation, but indirect genetic technologies, such as biosynthetic drugs. Second, we should try to anticipate the enhancement temptations of new therapies. Such anticipation may help us in shaping the marketing, availability, or other aspects of those technologies. Third, we should promote the adoption of appropriate public and professional policies. Finally, we should provide public education and dialogue to encourage personal ethical reflection on the appropriate uses and limits of genetic-enhancement technologies.