Lifeboat Foundation

Training datasets are very important for experimenting with varied data to train new AI models. However, many commonly used public data sets contain labeling errors. This makes it challenging to train robust models, particularly for novel tasks. Many researchers use techniques such as employing a variety of data quality control procedures to overcome these shortcomings. However, there is no centralized repository consisting of examples of using these strategies.

Meta AI researchers have recently released Mephisto. It is a new platform to collect, share, and iterate on the most promising approaches to collecting training datasets for AI models. Researchers can exchange unique collecting strategies with Mephisto in a reusable and iterable format. It also allows them to change out components and quickly locate the exact annotations required, minimizing the barrier to custom task creation.

The team uncovers many common pathways for driving a complex annotation activity from concept to data collection in Mephisto. In addition to improving the quality of datasets, Mephisto also enhances the experience of the researchers and annotators who created the data set.

A new approach to in-memory computing proposes a new set up to create an artificial synapse that can both store and process data.

In this blossoming era of AI, efficient computational approaches to processing and storing large amounts of data are required. However, current computer designs have inherent performance limitations.

In recent years, research has been focused on the development of alternative computing architectures that mimic the brain. These devices, called neuromorphic computers, circumvent many of the issues associated with the traditional von Neumann architecture, which has been around since 1945 and is composed of processing and memory units.

Speculate to accumulate lifespan – how crypto-conglomerate Moon Rabbit is going bigger and better for everyone.

Engineers have discovered a way to more than double the lifespan of batteries used in smartphones and electric cars.

The battery breakthrough was successfully demonstrated by researchers at the University of Queensland in Australia, who increased the lifespan of a lithium-ion (li-ion) battery from several hundred charge/ discharge cycles, to more than 1,000.

“Our process will increase the lifespan of batteries in many things, from smartphones and laptops, to power tools and electric vehicles,” said Professor Lianzhou Wang from the Australian Institute for Bioengineering and Nanotechnology.

So-called energy-based models, which borrow concepts from statistical physics, may lead the way to ‘abstract prediction,’ says Yann LeCun, allowing for a ‘unified world model’ for AI capable of planning.

Using the Hyper-CEST NMR technique, the team led by Leif Schröder from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Deutsches Krebsforschungszentrum (DKFZ) has managed to reveal two previously little researched variants of a type of transport container from the class of metal–organic polyhedra (MOPs). The researchers want to use this knowledge to develop a novel type of contrast agent in MR (magnetic resonance) imaging.

The concept of a modular construction system proves useful in many applications for assembling complex structures for specific functions from individual, repeated sub-units. In chemistry, the principle can be used to construct a self-assembling network from smaller molecular units that acts as a transport container of a defined size. For example, several metal ions can be linked with organic molecules. These MOPs (metal–organic polyhedra) are used, for instance, to capture greenhouse gases or to pave the way for more effective chemotherapeutic agents by loading them with certain drugs, which they then release in the tumor. Several aspects of the behavior of these structures have not yet been adequately explored. This is partly because there are not always appropriate techniques available to observe the loading and unloading of these MOPs at the molecular level —often, no differences can be measured between the empty and loaded variants for either the container or its contents.

In cooperation with a team from the University of Oulu in Finland, Leif Schröder’s research group has now investigated MOPs that spontaneously assemble in solution from iron ions and an organic compound to form tetrahedra. In the process, the organic struts can be attached differently to the iron “nodes.” Essentially, this influences the properties of MOPs, such as their capacity to kill tumor cells. In the case of the MOP under study, however, it was previously thought that only one of the three theoretically predicted variants existed. The other two variants were considered too unstable because no analytical methods were able to detect them. Using a new method of magnetic resonance (hyper-CEST NMR), Schröder’s team member Jabadurai Jayapaul has now succeeded in demonstrating that these previously unknown variants do exist.

Mar 31, 2022

Our 91st episode with a summary and discussion of last week’s big AI news!
Outline:

Continue reading “DeepMind Mafia, DishBrain, PRIME, ZooKeeper AI, Instant NeRF” »

Axiom Space has bold plans to send private citizens into space, as a stepping stone to developing a complete private space station.

GABAergic dysfunctions have been implicated in the pathogenesis of schizophrenia, especially the associated cognitive impairments. The GABA synthetic enzyme glutamate decarboxylase 67-kDa isoform (GAD67) encoded by the GAD1 gene is downregulated in the brains of patients with schizophrenia. Furthermore, a patient with schizophrenia harboring a homozygous mutation of GAD1 has recently been discovered. However, it remains unclear whether loss of function of GAD1 leads to the symptoms observed in schizophrenia, including cognitive impairment. One of the obstacles faced in experimental studies to address this issue is the perinatal lethality of Gad1 knockout (KO) mice, which precluded characterization at the adult stage. In the present study, we successfully generated Gad1 KO rats using CRISPR/Cas9 genome editing technology.