Lifeboat Foundation

Many of the all-too-familiar symptoms of aging can be attributed to a build-up of senescent cells, those which have stopped dividing. In a new study, researchers in Japan have identified a protein specific to these cells and developed a vaccine that can clear them away, with tests on mice reducing the effects of aging.

Cells cannot keep dividing forever – eventually they accumulate too much DNA damage through environmental stress, so the body shuts them down and flags them to be cleared out by the immune system. This seems to be an evolutionary defense mechanism against cells turning cancerous.

However, even immune cells aren’t immune from this process, and as they become senescent themselves the immune system gradually loses the ability to clear out senescent cells. As these inactive cells accumulate in the body, they contribute to symptoms of aging and the diseases that come with it.

After a successfull simulated launch countdown on January 24, only a few tests remain for NASA’s big Moon rocket.

“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” said Bennett.

The heart was provided by Revivicor, a company based in Virginia that has been engineering pig organs for roughly two decades. In several experiments for pig-to-baboon transplants, the organs survived up to nine months, until the animals passed away due to a lung infection unrelated to the transplant.

Overall, the heart had 10 hefty genetic edits. Three of them wiped out sugar molecules on the outside of cells that provoke an immune response. Six bolstered the chance of the human host accepting the heart—amping up an anti-inflammatory response, preventing blood vessel damage, and dampening any antibodies against the organ. Finally, the last edit limited the pig heart’s size. Although it generally matched the size of a human heart, the team wanted to prevent the pig organ from overgrowth inside Bennett’s chest once it was transplanted—something they previously noticed happened in baboons.

Over the last year home prices have skyrocketed (along with prices of almost everything else), leaving millions of people unable to afford to move or to change their housing situation. Mortgage lender Freddie Mac estimated last year that the US has a housing supply shortage of 3.8 million homes. It’s partly Covid-related; construction has slowed due to labor shortages, high raw material costs, and supply chain issues—but the problem predates the pandemic, as demand for homes was already outpacing supply in 2019.

Middle-and low-income families have been hit hardest by the housing shortage. In an effort to assist those in need, Habitat for Humanity launched an initiative last year to incorporate 3D printing into its construction process to cut costs. The first home was completed last month, and a family moved in just before Christmas.

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The amazing thing about radio transients is that if you have enough frequency coverage, you can work out how far away they are. This is because lower radio frequencies arrive slightly later than higher ones depending on how much space they’ve traveled through.

Our new discovery lies about 4,000 light years away—very distant, but still in our galactic backyard.

We also found the radio pulses were almost completely polarized. In astrophysics this usually means their source is a strong magnetic field. The pulses were also changing shape in just half a second, so the source has to be less than half a light second across, much smaller than our sun.

For millions of patients who have lost limbs – for reasons ranging from diabetes to trauma – the possibility of regaining function through natural regeneration remains out of reach. The regrowth of legs and arms remains limited to animals such as salamanders and the realm of science fiction.

However, a new study published in the journal Science Advances, by scientists at Tufts University and Harvard University’s Wyss Institute, has brought us a step closer to the goal of regenerating human limbs.

On adult frogs, which are naturally unable to regenerate limbs, a research team succeeded in triggering regrowth of a lost leg using a five-drug cocktail applied in a silicone wearable bioreactor dome that seals over the stump for just 24 hours. That brief treatment sets in motion an 18-month period of regrowth that eventually restores a functional leg.

Royal BAM announces ‘world’s first’ fully electric asphalt road paver with dual electric motors and a pair of massive 270 kWh batteries!

Royal BAM announces ‘world’s first’ fully electric asphalt road paver with dual electric motors and a pair of massive 270 kWh batteries!

Dutch civil engineering company Royal BAM has announced a fully-electric asphalt spreading road paver, which will save more than 93,000 kilograms of CO₂ and 115,000 grams of nitrous oxide emissions compared to its bio-diesel counterparts.

Working together with partners at Wirtgen and New Electric, BAM has replaced the vegetable-oil sourced, bio-diesel powered Volvo Penta Stage V engines with an electric drive, consisting of two “smartly switched electric motors” that pull electrons from a massive 270 kWh battery. For those you keeping score, that’s more than twice as big as the battery used in the 500-mile range Lucid Air electric sedan. (!)

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‘A watershed in furthering our understanding of these structures,’ researcher says.

An unprecedented new telescope image of the Milky Way galaxy’s turbulent center has revealed nearly 1,000 mysterious strands, inexplicably dangling in space.

Stretching up to 150 light years long, the one-dimensional strands (or filaments) are found in pairs and clusters, often stacked equally spaced, side by side like strings on a harp. Using observations at radio wavelengths, Northwestern University ’s Farhad Yusef-Zadeh discovered the highly organized, magnetic filaments in the early 1980s. The mystifying filaments, he found, comprise cosmic ray electrons gyrating the magnetic field at close to the speed of light. But their origin has remained an unsolved mystery ever since.