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Targeting calcium signaling in neurons represents a promising therapeutic approach for treating a rare form of schizophrenia, according to a Northwestern Medicine study published in Biological Psychiatry.

“This is the first time that human are made and characterized from with the 16p11.2 duplication, one of the most prominent genetic risk factors in schizophrenia, and the first time that signaling is found as a central abnormality in schizophrenia neurons,” said Peter Penzes, Ph.D., the Ruth and Evelyn Dunbar Professor of Psychiatry and Behavioral Sciences and senior author of the study.

Schizophrenia is characterized by auditory and visual hallucinations, delusions, and trouble with forming and sorting thoughts, which severely impacts productivity and overall quality of life. The disease, which affects roughly one percent of the , has strong genetic associations, however the exact genes involved are unknown.

Quantum simulations of the hydroxide anion and hydroxyl radical are reported, employing variational quantum algorithms for near-term quantum devices. The energy of each species is calculated along the dissociation curve, to obtain information about the stability of the molecular species being investigated. It is shown that simulations restricted to valence spaces incorrectly predict the hydroxyl radical to be more stable than the hydroxide anion. Inclusion of dynamical electron correlation from nonvalence orbitals is demonstrated, through the integration of the variational quantum eigensolver and quantum subspace expansion methods in the workflow of N-electron valence perturbation theory, and shown to correctly predict the hydroxide anion to be more stable than the hydroxyl radical, provided that basis sets with diffuse orbitals are also employed.

The ERNIE bot could be China’s most notable entry in the race to create lifelike AI bots.

One of the world’s biggest AI (artificial intelligence) and internet firms, Baidu, had its shares skyrocket more than 14 percent on Tuesday after the Beijing-based search engine titan announced it would launch its own ChatGPT-style service.

What is ERNIE?


Getty Images.

The company’s “ERNIE Bot” AI chatbot, also known as “Wenxin Yiyan” in Chinese, will complete internal testing and launch in March. Much excitement has developed towards what may be China’s most notable entry in the race to create lifelike AI bots.

It will produce three times more energy in winter months.

AlpinSolar, a joint venture between three Swiss companies, has successfully completed installing 5,000 solar panels on the Lake Muttsee Dam in Switzerland, Reuters.

Sun and snow generate more energy.


AlpinSolar.

With a project like AlpinSolar, the Swiss have just begun their large-scale transition from nuclear power to green energy, as planned in 2011. Interesting Engineering has previously reported how Switzerland built a massive ‘water battery’ to store its renewable energy.