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Jan 20, 2022

New Virus-Like Particles Can Deliver CRISPR to Any Cell in the Body

Posted by in categories: bioengineering, biotech/medical, space travel

One critical difference? Unlike a Mars mission’s “seven minutes of terror,” during which the entry, descent, and landing occur too fast for human operators to interfere, gene therapy delivery is completely blind. Once inside the body, the entire flight sequence rests solely on the design of the carrier “spaceship.”

In other words, for gene therapy to work efficiently, smarter carriers are imperative.

This month, a team at Harvard led by Dr. David Liu launched a new generation of molecular carriers inspired by viruses. Dubbed engineered virus-like particles (eVLPs), these bubble-like carriers can deliver CRISPR and base editing components to a myriad of organs with minimal side effects.

Jan 20, 2022

Scientists achieve key elements for fault-tolerant quantum computation in silicon spin qubits

Posted by in categories: computing, quantum physics

Researchers from RIKEN and QuTech—a collaboration between TU Delft and the Netherlands Organisation for Applied Scientific Research (TNO)— have achieved a key milestone toward the development of a fault-tolerant quantum computer. They were able to demonstrate a two-qubit gate fidelity of 99.5 percent—higher than the 99 percent considered to be the threshold for building fault-tolerant computers—using electron spin qubits in silicon, which are promising for large-scale quantum computers as the nanofabrication technology for building them already exists. This study was published in Nature.

The world is currently in a race to develop large-scale quantum computers that could vastly outperform classical computers in certain areas. However, these efforts have been hindered by a number of factors, including in particular the problem of decoherence, or noise generated in the qubits. This problem becomes more serious with the number of qubits, hampering scaling up. In order to achieve a large-scale that could be used for useful applications, it is believed that a two-qubit gate fidelity of at least 99 percent to implement the surface code for error correction is required. This has been achieved in certain types of computers, using qubits based on superconducting circuits, trapped ions, and nitrogen-vacancy centers in diamond, but these are hard to scale up to the millions of qubits required to implement practical quantum computation with an error correction.

To address these problems, the group decided to experiment with a quantum dot structure that was nanofabricated on a strained silicon/silicon germanium quantum well substrate, using a controlled-NOT (CNOT) gate. In previous experiments, the gate fidelity was limited due to slow gate speed. To improve the gate speed, they carefully designed the device and tuned it by applying different voltages to the gate electrodes. This combined an established fast single-spin rotation technique using micromagnets with large two-qubit coupling. The result was a gate speed that was 10 times better than previous attempts. Interestingly, although it had been thought that increasing gate speed would always lead to better fidelity, they found that there was a limit beyond which increasing the speed actually made the fidelity worse.

Jan 19, 2022

Men Are Creating AI Girlfriends and Then Verbally Abusing Them

Posted by in categories: mobile phones, robotics/AI

Content warning: this story contains descriptions of abusive language and violence.

The smartphone app Replika lets users create chatbots, powered by machine learning, that can carry on almost-coherent text conversations. Technically, the chatbots can serve as something approximating a friend or mentor, but the app’s breakout success has resulted from letting users create on-demand romantic and sexual partners — a vaguely dystopian feature that’s inspired an endless series of provocative headlines.

Replika has also picked up a significant following on Reddit, where members post interactions with chatbots created on the app. A grisly trend has emerged there: users who create AI partners, act abusively toward them, and post the toxic interactions online.

Jan 19, 2022

Google’s $1.5 billion research center to “solve death”

Posted by in categories: biotech/medical, life extension, singularity

Google has been developing what is perhaps the company’s most ambitious project to date: a science startup that will pursue ‘solutions for aging’ with the intended goal of “solving death”.

Calico, a company directed by futurists to explore the concept of “singularity”, has partnered with pharmaceutical giants to research and trial new market drugs that target aging and development.

What is this new audacious project? Who is behind it? In the following feature, Ethan Nash explores.

Jan 19, 2022

To Elon Musk, on the Future of Our Brains

Posted by in categories: biotech/medical, Elon Musk, neuroscience

By: alfonso fasano & benjamin stecher.

The following was written out of a shared belief that there are only two things that can change the world. A big army and a big idea. This is a distillation of our big idea.

Dear Elon Musk.

Continue reading “To Elon Musk, on the Future of Our Brains” »

Jan 19, 2022

Elon Musk: Tesla could play a role in Artificial General Intelligence, decentralize Tesla Bot to avoid Terminator scenario

Posted by in categories: Elon Musk, robotics/AI

Elon Musk announced that he is thinking about involving Tesla in the creation of Artificial General Intelligence (AGI).

He also added that he plans on decentralizing the control of Tesla Bot to avoid a Terminator-like scenario.

For a few years now, Musk has been pushing the idea that Tesla is the world’s leading company when it comes to real-world applications of artificial intelligence.

Jan 19, 2022

Commentary: To avoid the superbug pandemic, we must fix the antibiotics business

Posted by in categories: biotech/medical, business

Doctors must be careful when they consider treating their patients with the newest antibiotics, because every time these drugs are used, bacteria have a chance to build resistance. As a result, new antibiotics are generally used sparingly–leaving antibiotic companies with little chance of selling enough doses to recoup their investment.


If scientists don’t discover new antibiotics soon, the world will eventually return to the pre-antibiotic era when simple cuts could kill.

Jan 19, 2022

Delivery robots get airbags to protect you in case of collision

Posted by in categories: biotech/medical, food, robotics/AI

Autonomous vehicle maker Nuro has added external airbags to its self-driving delivery robots to protect pedestrians — but there’s reason to be skeptical about their effectiveness.

Drivers wanted: During the pandemic, more people started ordering their food, groceries, and other goods for delivery rather than venturing into stores and restaurants for them.

Continue reading “Delivery robots get airbags to protect you in case of collision” »

Jan 19, 2022

Google’s Incredible New Quantum Computer Company — SandBox

Posted by in categories: quantum physics, robotics/AI

Sandbox is the newest Quantum Computer company straight from Google which is focusing on the newly discovered Time Crystals which are posed to revolutionize computers in terms of efficiency and performance. Sandbox is separate from Google’s quantum computing team in Santa Barbara, and focuses on software and experimental quantum projects. The unit is currently led by Jack Hidary.

TIMESTAMPS:
00:00 Google’s Newest Project.
01:07 Google’s Goal with Quantum Computers.
03:29 Google’s New Company “SandBox“
04:35 What can it be used for?
07:41 Last Words.

#google #quantum #ai

Jan 19, 2022

Autonomous battery-powered rail cars could steal shipments from truckers

Posted by in categories: robotics/AI, transportation

Advances in batteries, autonomy could extend the reach of freight railroads.