Lifeboat News: The Blog – Safeguarding Humanity

Beer Ingredient May Inhibit Clumping of Alzheimer’s Protein

Posted by Nicholi Avery in biotech/medical, chemistry, food, health, neuroscience

Nov 14
2022

Cheers!

𝐁𝐞𝐞𝐫 𝐈𝐧𝐠𝐫𝐞𝐝𝐢𝐞𝐧𝐭 𝐌𝐚𝐲 𝐈𝐧𝐡𝐢𝐛𝐢𝐭 𝐂𝐥𝐮𝐦𝐩𝐢𝐧𝐠 𝐨𝐟 𝐀𝐥𝐳𝐡𝐞𝐢𝐦𝐞𝐫’𝐬 𝐏𝐫𝐨𝐭𝐞𝐢𝐧

𝘽𝙚𝙚𝙧 𝙞𝙨 𝙤𝙣𝙚 𝙤𝙛 𝙩𝙝𝙚 𝙤𝙡𝙙𝙚𝙨𝙩 𝙖𝙣𝙙 𝙢𝙤𝙨𝙩 𝙥𝙤𝙥𝙪𝙡𝙖𝙧 𝙗𝙚𝙫𝙚𝙧𝙖𝙜𝙚𝙨 𝙞𝙣 𝙩𝙝𝙚 𝙬𝙤𝙧𝙡𝙙, 𝙬𝙞𝙩𝙝 𝙨𝙤𝙢𝙚 𝙥𝙚𝙤𝙥𝙡𝙚 𝙡𝙤𝙫𝙞𝙣𝙜 𝙖𝙣𝙙 𝙤𝙩𝙝𝙚𝙧𝙨 𝙝𝙖𝙩𝙞𝙣𝙜 𝙩𝙝𝙚 𝙙𝙞𝙨𝙩𝙞𝙣𝙘𝙩, 𝙗𝙞𝙩𝙩𝙚𝙧 𝙩𝙖𝙨𝙩𝙚 𝙤𝙛 𝙩𝙝𝙚 𝙝𝙤𝙥𝙨 𝙪𝙨𝙚𝙙 𝙩𝙤 𝙛𝙡𝙖𝙫𝙤𝙧 𝙞𝙩𝙨 𝙢𝙖𝙣𝙮 𝙫𝙖𝙧𝙞𝙚𝙩𝙞𝙚𝙨. 𝘽𝙪𝙩 𝙖𝙣 𝙚𝙨𝙥𝙚𝙘𝙞𝙖𝙡𝙡𝙮 “𝙝𝙤𝙥𝙥𝙮” 𝙗𝙧𝙚𝙬 𝙢𝙞𝙜𝙝𝙩 𝙝𝙖𝙫𝙚 𝙪𝙣𝙞𝙦𝙪𝙚 𝙝𝙚𝙖𝙡𝙩𝙝 𝙗𝙚𝙣𝙚𝙛𝙞𝙩𝙨. 𝙍𝙚𝙘𝙚𝙣𝙩 𝙧𝙚𝙨𝙚𝙖𝙧𝙘𝙝 𝙥𝙪𝙗𝙡𝙞𝙨𝙝𝙚𝙙 𝙞𝙣 𝘼𝘾𝙎 𝘾𝙝𝙚𝙢𝙞𝙘𝙖𝙡 𝙉𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙘𝙚 𝙧𝙚𝙥𝙤𝙧𝙩𝙨 𝙩𝙝𝙖𝙩 𝙘𝙝𝙚𝙢𝙞𝙘𝙖𝙡𝙨 𝙚𝙭𝙩𝙧𝙖𝙘𝙩𝙚𝙙 𝙛𝙧𝙤𝙢 𝙝𝙤𝙥 𝙛𝙡𝙤𝙬𝙚𝙧𝙨 𝙘𝙖𝙣, 𝙞𝙣 𝙡𝙖𝙗 𝙙𝙞𝙨𝙝𝙚𝙨, 𝙞𝙣𝙝𝙞𝙗𝙞𝙩 𝙩𝙝𝙚 𝙘𝙡𝙪𝙢𝙥𝙞𝙣𝙜 𝙤𝙛 𝙖𝙢𝙮𝙡𝙤𝙞𝙙 𝙗𝙚𝙩𝙖 𝙥𝙧𝙤𝙩𝙚𝙞𝙣𝙨, 𝙬𝙝𝙞𝙘𝙝 𝙞𝙨 𝙖𝙨𝙨𝙤𝙘𝙞𝙖𝙩𝙚𝙙 𝙬𝙞𝙩𝙝 𝘼𝙡𝙯𝙝𝙚𝙞𝙢𝙚𝙧’𝙨 𝙙𝙞𝙨𝙚𝙖𝙨𝙚 (𝘼𝘿).

Beer is one of the oldest and most popular beverages in the world, with some people loving and others hating the distinct, bitter taste of the hops used to flavor its many varieties. But an especially “hoppy” brew might have unique health benefits. Recent research published in ACS Chemical Neuroscience reports that chemicals extracted from hop flowers can, in lab dishes, inhibit the clumping of amyloid beta proteins, which is associated with Alzheimer’s disease (AD).

Continue reading “Beer Ingredient May Inhibit Clumping of Alzheimer’s Protein” | >

Lab discovers new pathway for antimicrobial peptides

Posted by Genevieve Klien in biotech/medical

Nov 14
2022

Researchers in the Princeton University Department of Chemistry have discovered a new multi-step pathway through which bacteria found in the mammalian gut produce antimicrobial peptides.

The newly identified biosynthetic pathway transforms a biologically inert peptide into structurally complex antibiotics, which they call enteropeptins. Enteropeptins are a class of ribosomally synthesized peptide natural products, referred to as RiPPs.

The core structure of these products is synthesized by the ribosome, which is limited to the 20 canonical amino acids. The Mo Lab discovered and characterized new metalloenzymes capable of converting arginine, a canonical amino acid, into N-methylornithine, a noncanonical amino acid, within enteropeptin.

Read more | >

World’s largest solar telescope array is now complete

Posted by Genevieve Klien in space

Nov 14
2022

China’s Daocheng Solar Radio Telescope is among a suite of instruments the country has built in the past three years to study the Sun.

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The Gold In Our Galaxy May Be 10 Billion Years Old, Say Scientists

Posted by Genevieve Klien in physics, space, supercomputing

Nov 14
2022

The hundreds of gold-rich stars discovered in our Milky Way galaxy may have come from smaller galaxies that merged 10 billion years ago, according to new simulations by a supercomputer.

Using the ATERUI II supercomputer in the Center for Computational Astrophysics at the National Astronomical Observatory of Japan, scientists at Tohoku University and the University of Notre Dame developed new simulations of galaxy formation with the highest resolution yet.

The paper was published this week in the Monthly Notices of the Royal Astronomical Society.

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Researchers discover unique peptides with anti-cancer potential

Posted by Genevieve Klien in biotech/medical, chemistry

Nov 14
2022

A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.

The research was led by Professor Ashraf Brik and post-doctoral fellows Dr. Ganga B. Vamisetti and Dr. Abbishek Saha from the Schulich Faculty of Chemistry at the Technion—Israel Institute of Technology in Haifa, along with Professor Nabieh Ayoub from the Technion’s Faculty of Biology and Professor Hiroaki Suga from the University of Tokyo.

Peptides are short chains of amino acids linked by peptide bonds, the name given to chemical bonds formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule.

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Ultra-thin smartphone touchscreens could be printed like a newspaper

Posted by Quinn Sena in materials, mobile phones

Nov 14
2022

face_with_colon_three circa 2020.

Scientists in Australia have developed a new type of electronic material that is touch-responsive and just a fraction of the thickness of current smartphone screens. This could see it one day find use in next-generation mobile devices, and because of its incredible thinness and flexibility, could be manufactured at large scale using roll-to-roll (R2R) processing like a printed newspaper.

The breakthrough comes from researchers at RMIT University, who began with a material commonly used in today’s mobile touchscreens called indium-tin oxide. This transparent material is highly conductive but does have its shortcomings, chiefly that it is very brittle, so the team sought to give it better pliability by greatly reducing its thickness.

“We’ve taken an old material and transformed it from the inside to create a new version that’s supremely thin and flexible,” says lead researcher Dr Torben Daeneke. “You can bend it, you can twist it, and you could make it far more cheaply and efficiently than the slow and expensive way that we currently manufacture touchscreens.”

Continue reading “Ultra-thin smartphone touchscreens could be printed like a newspaper” | >

Recent searches for light fermionic dark matter by the PandaX-4T collaboration

Posted by Shubham Ghosh Roy in cosmology, particle physics

Nov 14
2022

Teams of astrophysicists worldwide are trying to observe different possible types of dark matter (DM), hypothetical matter in the universe that does not emit, absorb or reflect light and would thus be very difficult to detect. Fermionic DM, however, which would be made of fermions, has so far been primarily explored theoretically.

The PandaX Collaboration, a large consortium of researchers in China involved in the PandaX-4T experiment, has recently carried out a study aimed at extending the sensitive mass window for experiments aimed at directly detecting fermionic DM from above GeV to MeV or even keV ranges.

The team recently published two papers in Physical Review Letters outlining the results of the two searches for the absorption of fermionic DM using data gathered as part of the Panda X-4T experiment, a large-scale research effort aimed at detecting DM using a dual-phase time projection chamber (TPC) in China.

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Meet Orbit, the Interactive Robot That Looks to Help Children With Autism Spectrum Disorders Develop Social Skills

Posted by Kelvin Dafiaghor in robotics/AI

Nov 14
2022

Orbit, an interactive robot, helps teach children on the autism spectrum to develop social appropriateness and emotion via storytelling, physical interaction, and visual communication.

The hand-sized robot smiles and encourages users to press a button on its back, reacting with a beaming smile if pressed gently, and with a sad face if the interaction is too hard.

Hey there. Allow me to introduce you to your new companion, Orbit, a robot you can play with and listen to.

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Mapping Brain Connections Reinforces Theories On Human Cognition

Posted by Dan Breeden in mapping, neuroscience

Nov 14
2022

17:12 minutes.

After decades of research using sophisticated brain imaging, there’s a growing consensus among neuroscientists that understanding the connections between brain regions may be even more important than the functions of the regions themselves. When it comes to understanding human cognition, the whole is greater than the sum of its parts.

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Is Physical Law an Alien Intelligence?

Posted by Dan Breeden in alien life, existential risks, mobile phones, particle physics, singularity

Nov 14
2022

Perhaps Arthur C. Clarke was being uncharacteristically unambitious. He once pointed out that any sufficiently advanced technology is going to be indistinguishable from magic. If you dropped in on a bunch of Paleolithic farmers with your iPhone and a pair of sneakers, you’d undoubtedly seem pretty magical. But the contrast is only middling: The farmers would still recognize you as basically like them, and before long they’d be taking selfies. But what if life has moved so far on that it doesn’t just appear magical, but appears like physics?

After all, if the cosmos holds other life, and if some of that life has evolved beyond our own waypoints of complexity and technology, we should be considering some very extreme possibilities. Today’s futurists and believers in a machine “singularity” predict that life and its technological baggage might end up so beyond our ken that we wouldn’t even realize we were staring at it. That’s quite a claim, yet it would neatly explain why we have yet to see advanced intelligence in the cosmos around us, despite the sheer number of planets it could have arisen on—the so-called Fermi Paradox.

For example, if machines continue to grow exponentially in speed and sophistication, they will one day be able to decode the staggering complexity of the living world, from its atoms and molecules all the way up to entire planetary biomes. Presumably life doesn’t have to be made of atoms and molecules, but could be assembled from any set of building blocks with the requisite complexity. If so, a civilization could then transcribe itself and its entire physical realm into new forms. Indeed, perhaps our universe is one of the new forms into which some other civilization transcribed its world.

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