Lifeboat Foundation

Summary: Brief exposure to Rapamycin, a promising anti-aging drug that has positive effects on health and lifespan, has the same effect as long-term exposure to the drug in animal models. The findings pave the way for testing the effects of short-term rapamycin exposure on the lifespan of humans.

Source: Max Planck Institute.

Imagine you could take a medicine that prevents the decline that come with age and keeps you healthy. Scientists are trying to find a drug that has these effects.

More people in the U.S. are now smoking marijuana than cigarettes, according to a Gallup poll.

Cigarette use has been trending downward during the past decades, with only 11% of Americans saying they smoke them in a poll conducted July 5 to 26, compared to 45% in the mid-1950s.

Sixteen percent of Americans say they smoke marijuana, with 48% saying they have tried it at some point in their lives. In 1969, only 4% of Americans said they smoked marijuana.

Luke barnes, lecturer in physics, western sydney university miroslav filipovic, professor, western sydney university ray norris, professor, school of science, western sydney university velibor velović, phd candidate, western sydney university.

Astronomers at Western Sydney University have discovered one of the biggest black hole jets in the sky.

Spanning more than a million light years from end to end, the jet shoots away from a black hole with enormous energy, and at almost the speed of light. But in the vast expanses of space between galaxies, it doesn’t always get its own way.

Less than a week after a Bill Gates-backed MIT startup announced it had successfully tested a massive magnet that could allow them to achieve “net energy” with their nuclear fusion reactor, scientists at France’s International Thermonuclear Experimental Reactor (ITER) received the first part of another huge magnet, an AP report explains.

That magnet is so strong that its American manufacturer claims it can lift an aircraft carrier. When it is fully assembled it will be almost 60 feet (20 meters) tall and 14 feet (over four meters) in diameter, and it could be the key to providing practically limitless energy via nuclear fusion.

The more we understand how cells produce shape and form, the more inadequate the idea of a genomic blueprint looks by Philip Ball + BIO.

Osaka Metropolitan University scientists have developed a simple, rapid method to simultaneously identify multiple food poisoning bacteria, based on color differences in the scattered light by nanometer-scaled organic metal nanohybrid structures (NHs) that bind via antibodies to those bacteria. This method is a promising tool for rapidly detecting bacteria at food manufacturing sites and thereby improving food safety. The findings were published in Analytical Chemistry.

According to the World Health Organization (WHO), every year food poisoning affects 600 million people worldwide—almost 1 in every 10 people—of which 420,000 die. Bacterial tests are conducted to detect food poisoning bacteria at food manufacturing factories, but it takes more than 48 hours to obtain results due to the time required for a bacteria incubation process called culturing. Therefore, there remains a demand for rapid testing methods to eliminate food poisoning accidents.

Responding to this need, the research team led by Professor Hiroshi Shiigi at the Graduate School of Engineering, Osaka Metropolitan University, utilized the optical properties of organic metal NHs—composites consisting of polyaniline particles that encapsulate a large number of metal nanoparticles—to rapidly and simultaneously identify food poisoning-inducing bacteria called enterohemorrhagic Escherichia coli (E. coli O26 and E. coli O157) and Staphylococcus aureus.

A new method that increases the signal from CRISPR-based diagnostic tests, removing the need for amplification of DNA or RNA in a sample, could be used to quickly diagnose heart attacks and differentiate between cancer types.

A discovery made by researchers at the University of California, Irvine on how a certain protein is activated in tumor cells may lead to more effective treatments for some of the most deadly types of cancer. The finding, which was led by scientists at the School of Biological Sciences, may potentially result in treatment options for the especially dangerous melanoma and pancreatic adenocarcinoma, as well as the most common type of childhood brain cancer and adult skin cancer. The study was published in the journal Life Science Alliance.

The GLI1 protein, which is essential for cell development but has also been linked to a number of cancers, was the subject of the finding. The Hedgehog signaling pathway, also known as HH, usually activates GLI1. However, scientists have known for almost a decade that crosstalk, or interaction, between HH and the mitogen-activated protein kinase pathway, has a role in cancer.

“In some cases, proteins in one pathway can turn on proteins in another,” said lead author A. Jane Bardwell, a project scientist in UCI’s Department of Developmental and Cell Biology. “It’s a complex system. We wanted to understand the molecular mechanism that leads to GLI1 being activated by proteins in the MAPK pathway.”

Researchers from the University of Pennsylvania demonstrated in a proof-of-concept study that a hands-free device could successfully automate the treatment and removal of dental plaque and bacteria that cause tooth decay.

In the future, a shape-shifting robotic microswarm may serve as a toothbrush, rinse, and dental floss all in one. The technology, created by a multidisciplinary team at the University of Pennsylvania, has the potential to provide a brand-new, automated method for carrying out the repetitive but important daily duties of brushing and flossing. For people who lack the manual dexterity to efficiently clean their teeth alone, this system could be extremely helpful.

These microrobots are composed of iron oxide nanoparticles with catalytic and magnetic properties. Researchers were able to control their movement and configuration using a magnetic field to either produce bristle-like structures that remove dental plaque from the wide surfaces of teeth or elongated threads that can slide between teeth like a piece of floss. In both situations, the nanoparticles are driven by a catalytic reaction to release antimicrobials that eliminate harmful oral bacteria on site.