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Turn.bio has announced that its proprietary cellular reprogramming technology was able to significantly increase the proliferative and cytotoxic potential of premanufactured CAR-T cells in vitro.

Turn.bio, a developer of mRNA-based cellular reprogramming technologies, has announced preliminary results from its current trial. The announcement was made by the company’s co-founder, Prof. Vittorio Sebastiano, at the New Frontiers of RNA Nanotherapeutics conference at Houston Methodist Research Institute. These results show that the company’s proprietary Epigenetic Reprogramming of Aging (ERA) technology greatly increases the fitness of CAR-T cells, which are widely used in modern immunotherapy.

T cell exhaustion is a big problem.

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The Aging and Drug Discovery Conference (ARDD) 2022 is pleased to present Alex Zhavoronkov from Insilico, with the talk A case study of the application of Pharma. AI platform for discovery and development of dual-purpose therapeutics targeting aging and disease.

Held in Copenhagen at the glorious Ceremonial Hall, this meeting gathers the most prominent figures of the aging and longevity research field, from scientists to clinicians, investors, developers, and everything in between. The fast growth of the conference is evidence of its great quality of it. In 2022 we had around 400 people on-site, and many others joined through the web.

To find out more check www.agingpharma.org #ARDD #ARDD2022 #Longevity

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A compound that both inhibits the MRSA superbug and renders it more vulnerable to antibiotics in lab experiments has been discovered by researchers at the University of Bath in the UK.

Antibiotic resistance poses a major threat to human health around the world, and Staphylococcus aureus has become one of the most notorious multidrug-resistant pathogens. Led by Dr. Maisem Laabei and Dr. Ian Blagbrough at the University of Bath, scientists have discovered a compound that both inhibits the Methicillin-resistant Staphylococcus aureus (MRSA) superbug and renders it more vulnerable to antibiotics.

Staphylococcus aureus (staph) is a type of bacteria found on people’s skin. Staph bacteria are usually harmless, but they can cause serious infections that can lead to sepsis or death. Methicillin-resistant Staphylococcus aureus (MRSA) is a cause of staph infection that is difficult to treat because of resistance to some antibiotics.

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A team of researchers from the National University of Singapore (NUS) have made a serendipitous scientific discovery that could potentially revolutionize the way water is broken down to release hydrogen gas—an element crucial to many industrial processes.

The team, led by Associate Professor Xue Jun Min, Dr. Wang Xiaopeng and Dr. Vincent Lee Wee Siang from the Department of Materials Science and Engineering under the NUS College of Design and Engineering (NUS CDE), found that light can trigger a new mechanism in a catalytic material used extensively in , where water is broken down into and oxygen. The result is a more energy-efficient method of obtaining hydrogen.

This breakthrough was achieved in collaboration with Dr. Xi Shibo from the Institute of Sustainability for Chemicals, Energy and Environment under the Agency for Science, Technology and Research (A*STAR); Dr. Yu Zhigen from the Institute of High Performance Computing under A*STAR; and Dr. Wang Hao from the Department of Mechanical Engineering under the NUS CDE.

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Lex Fridman Podcast full episode: https://www.youtube.com/watch?v=cdiD-9MMpb0
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UK and Russia are once again at loggerheads, this is after a report emerged that former Prime Minister Liz Truss cell phone was hacked when se was the Foreign Minister. UK Opposition politicians are now calling for an investigation after Daily Mail reported that suspected Kremlin agents were behind the hawk.

#UK #Russia #liztruss.

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