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A major hallmark of Parkinson’s disease is the loss of dopamine-producing neurons in the brain, which in turn causes patients to lose motor control abilities. NYSCF – Robertson Stem Cell Investigator Alumna Malin Parmar, PhD, of Lund University, has spent a decade developing a cell therapy to replace these cells, and this revolutionary treatment (called ‘STEM-PD’) has just received approval for a Phase I/IIa clinical trial in Sweden.

“We are excited and looking forward to this clinical study of STEM-PD, hoping that it could potentially help reduce the significant burden of Parkinson’s disease. This has been a massive team effort for over a decade, and the regulatory approval is a major and important milestone,” said Dr. Parmar, who is a Professor of Developmental and Regenerative Neurobiology at Lund, in a statement.

Dr. Parmar’s innovative work towards a Parkinson’s cell therapy earned her the NYSCF – Robertson Stem Cell Investigator Award in 2016, which provided support for her lab’s research until 2021, including her work on STEM-PD.

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Join us on November 9 to learn how to successfully innovate and achieve efficiency by upskilling and scaling citizen developers at the Low-Code/No-Code Summit. Register here.

Forrester Research’s recently-released predictions report for artificial intelligence highlights what most have already observed: AI adoption has evolved from an emerging, nice-to-have trend to experiment with to a legitimate, must-do priority for enterprises.

Basically, get on board the AI train or be left behind.

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Regenerative medicine company Frequency Therapeutics is developing new drugs that activate our innate abilities to restore function and reverse degenerative diseases. The company is working on small molecules that selectively activate progenitor cells already present within our bodies to create healthy, functional tissues. Frequency’s initial focus is on hearing loss and multiple sclerosis, and the company has just completed enrolment of a Phase 2b trial in adults with acquired sensorineural hearing loss (SNHL).

Longevity. Technology: Frequency is focused on progenitor cells, which are like stem cells but can only make cells that belong to the same tissue or organ. While progenitor cells remain active in some of our organs and tissues, they can become dormant in others. Frequency’s small molecules are designed to selectively target and induce dormant progenitor cells to create specific cell types to restore tissue structure and function. We caught up with Frequency’s Chief Scientific Officer Dr Chris Loose to learn more.

Nasdaq-listed Frequency was founded in 2014, licensing technology developed by professors Robert Langer from MIT and Jeffrey Karp from Harvard Medical School.

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Dr talks taking hardcore science to market without biotech approval risk and the catalyst that is translational research.

We were lucky enough to attend the Longevity Investors Conference last month; this key event attracts those interested in learning about longevity investment opportunities and finding out more about the exciting directions in which the field is accelerating. To put it succinctly, as MIT Tech Review did recently, LIC “brings academic scientists and biotech companies together with deep-pocketed investors. We’re talking millionaires and billionaires.”

One of the driving forces behind the Longevity Investors Conference is Dr Tobias Reichmuth; a company-builder since the age of 21, Reichmuth has invested in more than 20 startups and is one of the founding partners of Maximon, the longevity company building. Along with his Maximon colleague Marc P Bernegger, Riechmuth launched the Longevity Investors Conference, and we couldn’t pass up the chance to grab some time with him to discuss the current longevity market.

Visit Longevity. Technology — https://bit.ly/3PwtH8Y

Continue reading “Tobias Reichmuth — the longevity market starts now” | >

Scientists from around the world have reconstructed the laws of gravity, to help get a more precise picture of the universe and its constitution.

The standard model of is based on General Relativity, which describes gravity as the curving or warping of space and time. While the Einstein equations have been proven to work very well in our solar system, they had not been observationally confirmed to work over the entire .

An international team of cosmologists, including scientists from the University of Portsmouth in England, has now been able to test Einstein’s theory of gravity in the outer-reaches of space.

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Sean Carroll: We might solve free will one day. But here’s why I doubt it.

Up next, The great free will debate ► https://youtu.be/3O61I0pNPg8

Debates about the existence of free will have traditionally been fought by two competing camps: those who believe in free will and those who don’t because they believe the Universe is deterministic.

Determinism is the thesis that every event — from when a volcano erupts to what cereal you buy at the supermarket — is a theoretically predictable result of the long chain of events that came before it. Free will, it was long thought, cannot exist in a world where all events are already causally determined.

Continue reading “Does free will violate the laws of physics? | Sean Carroll” | >

Less than 20 years ago, Konstantin Novoselov and Andre Geim first created two-dimensional crystals consisting of just one layer of carbon atoms. Known as graphene, this material has had quite a career since then.

Due to its exceptional strength, is used today to reinforce products such as tennis rackets, car tires or aircraft wings. But it is also an interesting subject for , as physicists keep discovering new, astonishing phenomena that have not been observed in other materials.

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