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Ever hear of the Turk —the 19th-century mechanism topped by a turbaned head that played chess against all comers? In fact, hidden inside was a diminutive chessmaster, one you might imagine deadpanning, “Eh, It’s a living.”

Then there’s its namesake, the Mechanical Turk —a 21st-century service offered by Amazon to mark up images on the Web with the help of crowdsourced freelancers. They, too, might intone, glassy-eyed, “It’s a living.”

Now we have a kind of Biological Turk. A mass of neurons act as a computer that mimics a human being playing the classic computer game Pong. The neurons, some taken from mouse embryos, others grown from human precursor cells, spread out into a one-layer, 800,000-cell mesh called a biological neural network, which lives in a giant petri dish called the DishBrain. There it interfaces with arrays of electrodes that form an interface to silicon hardware. Software mounted on that hardware provides stimulation and feedback, and the minibrain learns how to control a paddle on a simulated ping-pong table.

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“It’s like being able to see the mountain all at once—the whole landscape and the individual trees.” That’s how researcher Jun Ye describes direct frequency-comb absorption spectroscopy. Ye and his JILA/National Institute of Standards and Technology colleagues in Boulder, CO, used optical frequency combs to analyze complex gas mixtures for a forthcoming IEEE Transactions on Plasma Science paper on a novel cold-plasma sterilization method.

The system bathes surfaces—agar plates, plastic ID badges (a “major vector for pathogen transmission…currently not subject to any disinfection/sterilization procedures…”), biofilms, and mouse skin (free-radical-rich gases have been shown to disinfect wounds and speed healing)—and mixtures of plasma-derived ozone (O3), hydrogen peroxide (H2O2), nitrous oxide (N2O), and nitrogen dioxide (NO2). It appears to work well, deactivating most surface bacteria in 15 to 60 seconds.

A further object of the study, however, was to discover exactly which gas proportions provided the most effective sterilization. The mix of gases, each with its own pattern of absorption transitions, made monitoring the flow a challenge for conventional Fourier transform infrared (FTIR) absorption spectroscopy.

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As nanotechology burrows into an increasing number of medical technologies, new developments in nanoparticles point to the ways that treatments can today be nanotechnologically targeted. In one case, would-be end effectors on microrobots are aimed at clearing up cases of bacterial pneumonia. In another, a smart-targeting system may decrease clotting risks in dangerous cases of thrombosis.

Scientists from the University of California, San Diego, demonstrated antibiotic-filled nanoparticles that hitch a ride on microbots made of algae to deliver targeted therapeutics. Their paper was recently published in Nature Materials. As a proof of concept, the researchers administered antibiotic-laden microbots to mice infected with a potentially fatal variety of pneumonia (a strain that is common in human patients who are receiving mechanical ventilation in intensive-care settings). All infections in the treated mice cleared up within a week, while untreated mice died within three days.

The algae–nanoparticle hybrid microbots were effectively distributed to infected tissue through lung fluid and showed negligible toxicity. “Our goal is to do targeted drug delivery into more challenging parts of the body, like the lungs,” said bioengineering professor Liangfang Zhang in a press statement. “And we want to do it in a way that is safe, easy, biocompatible, and long lasting.”

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Boise, Idaho-based memory manufacturer Micron Technology says it has reached volume production of a 232-layer NAND flash-memory chip. It’s the first such chip to pass the 200-layer mark, and it’s been a tight race. Competitors are currently providing 176-layer technology, and some already have working chips with 200+ layers in hand.

The new Micron tech as much as doubles the density of bits stored per unit area versus competing chips, packing in 14.6 gigabits per square millimeter. Its 1-terabit chips are bundled into 2-terabyte packages, each of which is barely more than a centimeter on a side and can store about two weeks worth of 4K video.

With 81 trillion gigabytes (81 zettabytes) of data generated in 2021 and International Data Corp. (IDC) predicting 221 ZB in 2026, “storage has to innovate to keep up,” says Alvaro Toledo, Micron’s vice president of data-center storage.

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Memory and storage chip maker Micron Technology says it is shipping samples of the most bit-dense DRAM memory chips yet. Compared with its own previous generation, the 16-gigabit DRAM chip is 15 percent more power efficient and 35 percent more dense. Notably, Micron achieved the improvement without resorting to the most advanced chip-making technology, extreme ultraviolet lithography. The features that make up DRAM cells are not nearly as tiny as those on logic chips, but this advance shows that DRAM density could still shrink further in the future.

Micron says it is shipping samples of LPDDR5X chips, memory made for power-constrained systems such as smartphones. (LPDDR5X, unpacked: a revved-up twist on the low-power version of the fifth generation of the double-data-rate memory communications standard, capable of transferring 8.5 gigabits per second.) It’s the first chip made using Micron’s new manufacturing process, called 1-beta, which the company says maintains the lead it took a year ago over rivals, including Samsung and SK Hynix.

Manufacturing processes for DRAM and logic chips diverged decades ago, with logic chips shrinking transistors much more aggressively as the years went by, explains Jim Handy, a memory and storage analyst at Objective Analysis, in Los Gatos, Calif. The reason for the difference has to do with DRAM’s structure. DRAM stores a bit as charge in a capacitor. Access to each capacitor is gated by a transistor. But the transistor is an imperfect barrier, and the charge will eventually leak away. So DRAM must be periodically refreshed, restoring its bits before they drain away. In order to keep that refresh period reasonable while still increasing the density of memory, DRAM makers had to make some pretty radical changes to the makeup of the capacitor. For Micron and other major manufacturers, it now resembles a tall pillar and is made using materials not found in logic chips.

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