This Video Explains SMALL INTERFERING RNA (siRNA) and The Difference Between miRNA and siRNA.
Reference: https://www.researchgate.net/figure/Gene-silencing-mechanism…_282035687
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TMCs are responsible for all aspects of data generation from tissue collection and analysis to data integration and interpretation. We anticipate that TMCs will acquire and integrate imaging and omics data to benchmark, standardize and validate SnC maps at single-cell resolution for their assigned tissues. The TDA sites are responsible for development of innovative, new approaches and tools necessary to deeply phenotype SnCs in human tissues and model systems. Examples include multi-omics characterization of the 4D nucleome in SnCs, high-throughput quantification of telomere-associated foci, and in vivo detection of SnCs via positron emission tomography imaging. Once developed, these new technologies are expected to be applied broadly and collaboratively across multiple tissues by the TMCs. The CODCC will collect, store and curate all data and metadata generated by the TMCs and TDA sites. The CODCC is responsible for generating the computational models, and final atlas products as well as the tools to visualize and disseminate the data as a resource for the broad scientific community.
It is expected that SenNet will interface with other cell mapping programs such as Human Bimolecular Atlas Program (HuBMAP), Human Cell Atlas (HCA) and the Kidney Precision Medicine Project (KPMP). HuBMAP is an NIH Common Fund Initiative to develop the resources and framework to map the 30 trillion cells that make up the human body using protein identifiers of cell lineage. HCA is using single-cell and spatial transcriptomics to create cell reference maps defining the position, function and characteristics of all cells in the human body. The KPMP is an initiative of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) aimed at using state-of-the-art and emerging technologies to characterize renal biopsies from participants with acute kidney injury or chronic kidney disease to enable personalized approaches to their treatment.
A group of neuroscientists developed a test to detect a novel marker of Alzheimer’s.
Alzheimer’s disease is a disease that attacks the brain, causing a decline in mental ability that worsens over time. It is the most common form of dementia and accounts for 60 to 80 percent of dementia cases. There is no current cure for Alzheimer’s disease, but there are medications that can help ease the symptoms.
Many like watching videos. This is a good one. I love hearing Christian talk about his cars tech. #Futurist
The Koenigsegg Gemera is alive! An in-depth look at the world’s fastest four seater car with Christian von Koenigsegg sharing all things Gemera while casually parked next the new Jesko!
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Tesla leaked upcoming Supercharger locations opening in the United States. The Supercharger Network is one of the pillars of Tesla’s success in the EV market. So it’s no surprise that Tesla has been diligently expanding the Supercharger Network’s reach over the past year.
Supercharger tracker @MarcoRPTesla noted that Tesla “mistakenly” leaked the locations of at least 50 Supercharger installations in the United States and other areas.
Among the leaked sites was a Supercharger located in Kahului, Hawaii. The Aloha state was the last of the 50 United States to get a Supercharger station. Hawaii now has several Tesla Destination Chargers as well.
Oto_feja/iStock.
John DeLong and his colleagues at the University of Nebraska have discovered that a species of Halteria—microscopic ciliates prevalent in freshwater habitats worldwide—can consume a sizable number of infectious chloroviruses. For the first time, the team’s laboratory tests have also demonstrated that a virus-only diet, or “virovory,” can support an organism’s physiological growth and even population increase.
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In the future, humanity may embrace genetic engineering and cybernetic augmentation of mind and body, but what does this Transhuman future look like? And should we embrace or resist these paths?
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Transhuman brains are the melding of hyper-advanced electronics and super-artificial intelligence (AI) with neurobiological tissue. The goal is not only to repair injury and mitigate disease, but also to enhance brain capacity and boost mental function. What is the big vision, the end goal — how far can transhuman brains go? What does it mean for individual consciousness and personal identity? Is virtual immortality possible? What are the ethics, the morality, of transhuman brains? What are the dangers?
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